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T74986MRV03-070;化合物 MRV03-070MRV03-070
MRV03-070, acting as a biosynthetic precursor akin to precolibactin [1], is a colibactin-activating peptidase ClbP inhibitor with an inhibitory concentration (IC 50) value of 69 nM.
价 格:¥电议型 号:T74986产 地:中国大陆
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T74070NHC-triphosphate tetrasodium;化合物 NHC-triphosphate tetrasodiumNHC-triphosphate tetrasodium
NHC-triphosphate tetrasodium, the active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) in its triphosphate form, functions as a weak alternative substrate for viral polymerase, allowing its incorporation into HCV replicon RNA.
价 格:¥电议型 号:T74070产 地:中国大陆
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T73501MC0704;化合物 MC0704MC0704
MC0704 is a STAT3 inhibitor that demonstrates antitumor activity specifically in mouse breast cancer models, possessing an IC50 value of 2.13 μM. It is effective in inducing cell apoptosis and cell cycle arrest, making it a potential candidate for researching metastatic triple-negative breast cancer (mTNBC).
价 格:¥电议型 号:T73501产 地:中国大陆
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T73084BMS 310705;化合物 BMS 31070521-Aminoepothilone B;21-Aminoepothilone B
BMS 310705 (21-Aminoepothilone B), an Epothilone B analog, specifically targets malignancies including ovarian, renal, bladder, and lung carcinoma. It significantly induces apoptosis through the mitochondrial-mediated pathway [1].
价 格:¥电议型 号:T73084产 地:中国大陆
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T73070STAT3-IN-14;化合物 STAT3-IN-14STAT3-IN-14
STAT3-IN-14 is a STAT3 inhibitor and has STAT3 phosphorylation inhibitory activity. STAT3-IN-14 can directly bind to the hinge region of STAT3 [1] .
价 格:¥电议型 号:T73070产 地:中国大陆
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T73005PF-07054894;化合物 PF-07054894PF-07054894
PF-07054894 is a potent antagonist of the CCR6 and a targeted G protein-coupled receptor (GPCR), useful in the research of inflammatory bowel disease.
价 格:¥电议型 号:T73005产 地:中国大陆
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T72070B-Raf IN 14;化合物 B-Raf IN 14B-Raf IN 14
B-Raf IN 14 is a BRAF inhibitor.
价 格:¥电议型 号:T72070产 地:中国大陆
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T71707LRomergoline 2HCl;罗麦角林Romergoline 2HCl(107052-56-2 Free base)|||FCE 23884 2HCl;Romergoline 2HCl(10705
Romergoline 2HCl is a D1 agonist and D2 antagonist used in the study of Parkinson´s disease.
价 格:¥电议型 号:T71707L产 地:中国大陆
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T71186ORM-13070;化合物 ORM-13070ORM-13070
ORM-13070 is a selective antagonist radioligand for the α2C adrenoceptor subtype. ORM-13070 C-11 is under investigation in clinical trial.
价 格:¥电议型 号:T71186产 地:中国大陆
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T71070Itasetron HCl;化合物 Itasetron HClItasetron HCl
Itasetron HCl is a potent 5HT-3 receptor antagonist.
价 格:¥电议型 号:T71070产 地:中国大陆
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T70709FCE-27262;化合物 FCE-27262FCE-27262
FCE-27262 is a prostaglandin H2/thromboxane A2 receptor antagonist.
价 格:¥电议型 号:T70709产 地:中国大陆
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T70708U 92032;化合物 U 92032U 92032
U 92032 is a T-channel antagonist and antioxidant that inhibits lipid peroxidation.
价 格:¥电议型 号:T70708产 地:中国大陆
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T70707Paullone;化合物 PaullonePaullone
Paullone is an inhibitor of cyclin-dependent kinases (CDKs). The CDKs are a family of protein kinases that are involved in regulation of the cell cycle.
价 格:¥电议型 号:T70707产 地:中国大陆
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T70706APTO-253 isomer;化合物 APTO-253 isomerAPTO-253 isomer
APTO-253 isomer is an isomer of APTO-253 with the Fluoro-atom in 6-position. APTO-253 also known as LOR-253, LT-253, is a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1) with potential antitumor activity. MTF-1 inhibitor LOR-253 inhibits MTF-1 activity and thereby induces the expression of MTF-1 dependent tumor suppressor factor Kruppel like factor 4 (KLF4). This subsequently leads to the downregulation of cyclin D1, blocking cell cycle progression and prolifer
价 格:¥电议型 号:T70706产 地:中国大陆
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T70704RB-005;化合物 RB-005RB-005
RB-005 is a potent sphingosine kinase isoform 1 (SK1) inhibitor, which may serve as therapeutic agent for proliferative diseases, including hypertension. RB-005, (IC(50) = 3.6 μM), which also induced proteasomal degradation of SK1 in human pulmonary arterial smooth muscle cells.
价 格:¥电议型 号:T70704产 地:中国大陆
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T70703DK-139;化合物 DK-139DK-139
DK-139 is an inhibitor of NF-kappaB-mediated GROalpha expression, suppressing the TNFalpha-induced invasive capability of MDA-MB-231 human breast cancer cells.
价 格:¥电议型 号:T70703产 地:中国大陆
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T70702JQ1-Acid HCl;化合物 JQ1-Acid HClJQ1-Acid HCl
(+)-JQ-1 carboxylic acid is a potent bromodomain and extra terminal domain (BET) inhibitor. (+)-JQ-1 carboxylic has potential to be used as a precursor to synthesize PROTACs and other conjugates.
价 格:¥电议型 号:T70702产 地:中国大陆
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T70701CHDI340246;化合物 CHDI340246CHDI340246
CHDI-340246 is a potent and selective kynurenine mono-oxygenase (KMO) inhibitor.
价 格:¥电议型 号:T70701产 地:中国大陆
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T70700Calanolide B;化合物 Calanolide BCalanolide B
Calanolide B is one of a novel class of HIV-inhibiting coumarins from the tropical rainforest tree, Calophyllum lanigerum.
价 格:¥电议型 号:T70700产 地:中国大陆