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T7070Nomifensine maleate;诺米芬新马来酸盐Nomifensine (maleate)|||(±)-Nomifensine maleat;Nomifensine (maleate)|||诺
Nomifensine maleate (Nomifensine (maleate)) is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder.
价 格:¥电议型 号:T7070产 地:中国大陆
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T70613SLP120701 HCl;化合物 SLP120701 HClSLP120701 HCl
SLP120701 is a potent and selective sphingosine kinase 2 inhibitor. Sphingosine-1-phosphate (S1P) is a ubiquitous, endogenous small molecule that is synthesized by two isoforms of sphingosine kinase (SphK1 and 2). Intervention of the S1P signaling pathway has attracted significant attention because alteration of S1P levels is linked to several disease states including cancer, fibrosis, and sickle cell disease.
价 格:¥电议型 号:T70613产 地:中国大陆
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T70591PF1070A;化合物 PF1070APF1070A
PF1070A is a natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothionein.
价 格:¥电议型 号:T70591产 地:中国大陆
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T70070Cisapride tartrate;化合物 Cisapride tartrateCisapride tartrate
Cisapride tartrate is chemically related to metoclopramide, but unlike metoclopramide, it does not cross the blood-brain barrier or have antidopaminergic effects. Cisapride is a serotonin-4 (5-HT4) receptor agonist. Cisapride was indicated for the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease. The Food and Drug Administration (FDA) in America stopped the marketing of cisapride as of 14th July 2000. They had received at least 341 reports o
价 格:¥电议型 号:T70070产 地:中国大陆
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T69070Cephradine sodium;化合物 Cephradine sodiumCephradine sodium
Cephradine sodium is the salt form of Cephradine (free base), a semi-synthetic cephalosporin antibiotic. Cefradin inhibits the last stage of bacterial cell wall synthesis by binding to certain penicillin-binding proteins which results in cell lysis. Cell lysis is mediated by bacterial cell wall autolytic enzymes. Cefradin may interfere with autolysin inhibitors.
价 格:¥电议型 号:T69070产 地:中国大陆
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T68195SC 39070;化合物 SC 39070SC 39070
SC 39070 is a leukotriene D4 antagonist.
价 格:¥电议型 号:T68195产 地:中国大陆
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T68070Fezolamine;非唑拉明Fezolamine
Fezolamine is a novel orally available non-tricyclic compound with antidepressant activity. It is three to two times more selective in blocking synaptosomal uptake of [3H]norepinephrine than uptake of [4H]3-hydroxytryptamine or [3H]dopamine in vitro. It blocked the inhibitory effects of rifampicin and tetraphenyl in classical behavioral tests using monoamine-depleted animals.
价 格:¥电议型 号:T68070产 地:中国大陆
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T67766HHS-0701;化合物HHS-0701HHS-0701
HHS-0701 is a sulfur-triazole exchange (SuTEx) ligand. HHS-0701 is a potent inhibitor of tyrosine-reactive prostaglandin reductase 2 (PTGR2). HHS-0701 can block PTGR2 metabolism of the lipid substrate 15-Keto-PGE2.
价 格:¥电议型 号:T67766产 地:中国大陆
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T670701,2-Diarachidoyl-sn-glycero-3-PC;化合物 1,2-Diarachidoyl-sn-glycero-3-PC1,2-Diarachidoyl-sn-glycero-3-P
1,2-Diarachidoyl-sn-glycero-3-PC is a useful organic compound for research related to life sciences. The catalog number is T67070 and the CAS number is 61596-53-0.
价 格:¥电议型 号:T67070产 地:中国大陆
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T6689T0070907;化合物T0070907T0070907
T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.
价 格:¥电议型 号:T6689产 地:中国大陆
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T65070Chenodeoxycholic Acid (sodium salt);化合物 Chenodeoxycholic Acid (sodium salt)Chenodeoxycholic Acid (so
Chenodeoxycholic Acid (sodium salt) is a useful organic compound for research related to life sciences. The catalog number is T65070 and the CAS number is 2646-38-0.
价 格:¥电议型 号:T65070产 地:中国大陆
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T64351GI-560192;化合物GI-560192RL-0070933;RL-0070933
GI-560192 (RL-0070933) is a potent smo cilial modulator with an EC50 value of 0.02 ?M. GI-560192 modulates the translocation and/or accumulation of smoothened to the primary cilia by hedgehog signaling pathway.
价 格:¥电议型 号:T64351产 地:中国大陆
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T6430Calcifediol;25-羟基维生素 D3U 32070E|||25-hydroxy Vitamin D3|||RO 8-8892;25-羟基维生素 D3|||U 32070E|||25-hydr
Calcifediol (U 32070E)(Ki of 3.9 μM), a major circulating metabolite of vitamin D3, works as a competitive inhibitor. It (ED50=2 nM)also inhibits PTH secretion and mRNA.
价 格:¥电议型 号:T6430产 地:中国大陆
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T6420BMS-707035化合物BMS707035N-[(4-氟苯基)甲基1,6-二氢-5-羟基-1-甲基-6-氧代-2-(四氢-1,1-二氧-2H-1,2-噻嗪-2-基)-4-嘧啶甲酰胺
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.
价 格:¥电议型 号:T6420产 地:中国大陆
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T64070Pan-Trk-IN-3;化合物 Pan-Trk-IN-3Pan-Trk-IN-3
Pan-Trk-IN-3 is a potent, broad-spectrum inhibitor of Trk and its drug-resistant mutants, acting on TrkA (IC50: 2 nM), TrkB (IC50: 3 nM), TrkC (IC50: 2 nM), TrkAG595R (IC50: 21 nM), TrkAG667C (IC50: 26 nM), TrkAG667S (IC50: 5 nM), TrkAF589L (IC50: 7 nM) and TrkCG623R (IC50: 6 nM), TrkAG667S (IC50: 5 nM), TrkAF589L (IC50: 7 nM) and TrkCG623R (IC50: 6 nM). Pan-Trk-IN-3 induces apoptosis and has significant anti-tumour effects.
价 格:¥电议型 号:T64070产 地:中国大陆
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T63070EGFR-IN-45;化合物 EGFR-IN-45EGFR-IN-45
EGFR-IN-45 is a potent pan-inhibitor of the epidermal growth factor receptor (EGFR), acting on EGFR (IC50: 0.4 μM) and CDK2 (IC50: 1.6 μM). EGFR-IN-45 also inhibits the topoisomerases Topo I and Topo II. EGFR-IN-45 blocks the cell cycle of cancer cells in the pre-G1 phase and induces apoptosis.
价 格:¥电议型 号:T63070产 地:中国大陆
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T6275Obatoclax Mesylate;奥巴克拉盐酸盐Obatoclax|||GX15-070;Obatoclax|||GX15-070|||奥巴克拉甲磺酸盐
Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.
价 格:¥电议型 号:T6275产 地:中国大陆
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T62070HIV-1 inhibitor-31;化合物 HIV-1 inhibitor-31HIV-1 inhibitor-31
HIV-1 inhibitor-31 (compound 4) is a potent inhibitor of HIV-1. HIV-1 inhibitor-31 can be used in the study of AIDS.
价 格:¥电议型 号:T62070产 地:中国大陆
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T6129GSK-1070916;化合物GSK1070916GSK-1070916A|||GSK1070916;GSK-1070916A|||GSK1070916
GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related Aurora A-TPX2 complex. Phase 1.
价 格:¥电议型 号:T6129产 地:中国大陆
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T61070VU6010572;化合物 VU6010572VU6010572
VU6010572 is a highly potent and selective negative allosteric modulator of mGlu3, exhibiting an IC50 of 245 nM. Additionally, VU6010572 displays high central nervous system penetrance [1] [2].
价 格:¥电议型 号:T61070产 地:中国大陆