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T78896SHP2-IN-22；化合物 SHP2-IN-22SHP2-IN-22
SHP2-IN-22, a potent SHP2 allosteric inhibitor, exhibits an IC50 value of 17.7 nM and effectively suppresses proliferation, migration, and invasion in MIA PaCa-2 pancreatic cancer cells. This compound is utilized in the study of Kirsten rat sarcoma viral oncogene (KRAS) mutant cancer research [1].
价 格：￥电议型 号：T78896产 地：中国大陆
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T78894NLRP3-IN-21；化合物 NLRP3-IN-21NLRP3-IN-21
NLRP3-IN-21 (compound L38) is an inhibitor of the NLRP3 inflammasome that possesses anti-inflammatory properties. It suppresses the activation of the NLRP3 inflammasome and pyroptosis by inhibiting gasdermin D cleavage, ASC oligomerization, and the assembly of the NLRP3 inflammasome [1].
价 格：￥电议型 号：T78894产 地：中国大陆
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T78893Antifungal agent 78；化合物 Antifungal agent 78Antifungal agent 78
Antifungal agent 78 (compound 25am) exhibits potent activity, with an EC50 of 13.46 μM against Fusarium graminearum [1].
价 格：￥电议型 号：T78893产 地：中国大陆
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T78892Glutaminase C-IN-2；化合物 Glutaminase C-IN-2Glutaminase C-IN-2
Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM. By disrupting glutamine metabolism, this compound modulates cellular metabolites and elevates reactive oxygen species (ROS), exerting anticancer effects [1].
价 格：￥电议型 号：T78892产 地：中国大陆
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T78891SDH-IN-8；化合物 SDH-IN-8SDH-IN-8
SDH-IN-8 (compound G40) is a potent inhibitor of succinate dehydrogenase (SDH), demonstrating an IC50 value of 27 nM against porcine SDH and exhibits fungicidal properties [1].
价 格：￥电议型 号：T78891产 地：中国大陆
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T78890SDH-IN-7；化合物 SDH-IN-7SDH-IN-7
SDH-IN-7 (compound G28) is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 26 nM against porcine SDH and possesses fungicidal properties [1].
价 格：￥电议型 号：T78890产 地：中国大陆
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T7889C25-140；化合物C25-140C25-140
C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.
价 格：￥电议型 号：T7889产 地：中国大陆
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T78889Lysyl hydroxylase 2-IN-1；化合物 Lysyl hydroxylase 2-IN-1Lysyl hydroxylase 2-IN-1
"Lysyl Hydroxylase 2-IN-1 (compound 12) is a selective inhibitor of lysyl hydroxylase 2 (LH2) with an IC50 of approximately 300 nM and demonstrates specificity for LH2 over LH1 and LH3 [1]."
价 格：￥电议型 号：T78889产 地：中国大陆
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T78888LSD1-UM-109；化合物 LSD1-UM-109LSD1-UM-109
LSD1-UM-109 is a highly potent and reversible inhibitor of LSD1, demonstrating an IC50 of 3.1 nM. This compound exhibits strong antiproliferative activity, inhibiting cell growth with IC50 values of 0.6 nM in the MV4;11 acute leukemia cell line and 1.1 nM in the H1417 small-cell lung cancer cell line [1].
价 格：￥电议型 号：T78888产 地：中国大陆
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T78887ROS-IN-2；化合物 ROS-IN-2ROS-IN-2
ROS-IN-2 (compound 85), a seco-lupane triterpenoid derivative, inhibits reactive oxygen species (ROS) production and shields mitochondria from oxidative damage by curtailing the generation of oxidative stressors. It has applications in myocardial ischemia/reperfusion (MI/R) injury research [1].
价 格：￥电议型 号：T78887产 地：中国大陆
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T78886Chitin synthase inhibitor 14；化合物 Chitin synthase inhibitor 14Chitin synthase inhibitor 14
Chitin Synthase Inhibitor 14 (compound 4n), a potent chitin synthase (CHS) inhibitor, exhibits antifungal activity and is effective against drug-resistant fungal strains [1].
价 格：￥电议型 号：T78886产 地：中国大陆
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T78885Aβ-IN-8；化合物 Aβ-IN-8Aβ-IN-8
Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].
价 格：￥电议型 号：T78885产 地：中国大陆
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T78884Aβ-IN-7；化合物 Aβ-IN-7Aβ-IN-7
Aβ-IN-7 (compound 5a) acts as a potent inhibitor of Aβ aggregation, stabilizing Aβ monomers at 50 μM concentration to prevent them from forming larger oligomers and delaying the nucleation phase. Comparative studies demonstrate that Aβ-IN-7 more effectively inhibits Aβ fibril formation than Aβ-IN-8 at identical 50 μM concentrations [1].
价 格：￥电议型 号：T78884产 地：中国大陆
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T78883DprE1-IN-9；化合物 DprE1-IN-9DprE1-IN-9
DprE1-IN-9 (compound B18) is an efficient reversible inhibitor of DprE1, interacting with the enzyme´s receptor cavity. It exhibits potent antimycobacterial properties, demonstrating activity against both non-pathogenic H37Ra (MIC=0.18 ?g/mL) and pathogenic strains, including H37Rv, as well as clinical MDR and XDR isolates [1].
价 格：￥电议型 号：T78883产 地：中国大陆
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T78882NF-κB-IN-12；化合物 NF-κB-IN-12NF-κB-IN-12
NF-κB-IN-12 (compound 3h) serves as a potent inhibitor of NF-κB, exhibiting an IC50 value of 1.02 μM. It is applicable for research in acute lung injury [1].
价 格：￥电议型 号：T78882产 地：中国大陆
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T78881α-Glucosidase-IN-36；化合物 α-Glucosidase-IN-36α-Glucosidase-IN-36
α-Glucosidase-IN-36 (compound 5g) is a potent inhibitor of α-glucosidase, exhibiting an IC50 value of 6.69 ± 0.18 μM and inhibition constants Ki and Kis of 1.65 μM and 4.54 μM, respectively. It is hypothesized to suppress α-glucosidase activity by interacting with its active site and altering the enzyme´s secondary structure. The compound is relevant for use in research on type 2 diabetes mellitus (T2DM) [1].
价 格：￥电议型 号：T78881产 地：中国大陆
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T78880Tubulin/HDAC-IN-3；化合物 Tubulin/HDAC-IN-3Tubulin/HDAC-IN-3
Tubulin/HDAC-IN-3 (compound 12a) serves as a potent dual inhibitor of tubulin polymerization and HDAC1/8, exhibiting IC50 values of 5.4 μM for tubulin polymerization, and 0.155 and 0.177 μM for HDAC1 and HDAC8, respectively. Its mechanism of action includes obstructing the cell cycle, triggering apoptosis, and suppressing colony formation [1].
价 格：￥电议型 号：T78880产 地：中国大陆
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T7888Enpp-1-IN-1；化合物Enpp-1-IN-1Enpp-1-IN-1
Enpp-1-IN-1 is an inhibitor of Ectonucleotide pyrophosphatase-phosphodiesterase 1 (enpp-1)
价 格：￥电议型 号：T7888产 地：中国大陆
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T78879CXCR4-IN-2；化合物 CXCR4-IN-2CXCR4-IN-2
CXCR4-IN-2 (compound A1), a potent bifunctional fluorinated small molecule, inhibits CXCR4 and exhibits anticancer properties by exerting cytotoxicity (IC 50: 60 μg/mL; 72 h) and antiproliferative effects on mouse colorectal cancer (CRC) cells. It induces G2/M phase cell cycle arrest and apoptosis [1].
价 格：￥电议型 号：T78879产 地：中国大陆
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T78878α-Amylase/α-Glucosidase-IN-5；化合物 α-Amylase/α-Glucosidase-IN-5α-Amylase/α-Glucosidase-IN-5
α-Amylase/α-Glucosidase-IN-5 (compound 4l) functions as a dual inhibitor, effectively inhibiting both α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC50 values of 5.96 μM and 1.62 μM, respectively, exhibiting potential for antidiabetic activity [1].
价 格：￥电议型 号：T78878产 地：中国大陆
