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  • T16699PYZD-4409

    PYZD-4409 is a selective UBA1 inhibitor with an IC50 of 20 μM. PYZD-4409 induces cell death in malignant cells and is preferentially cytotoxic to malignant cells over normal hematopoietic cells.

    价 格：￥电议型 号：T16699产 地：中国大陆

  • T1656Vandetanib凡德他尼；ZD6474

    Vandetanib is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.

    价 格：￥电议型 号：T1656产 地：中国大陆

  • T16486Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZDPF-05231023

    PF-05231023 is a long-acting fibroblast growth factor 21 (FGF21) analog and is an FGF21-receptor agonist. It is also suitable for development as a potential treatment for T2DM.

    价 格：￥电议型 号：T16486产 地：中国大陆

  • T16162Mutated EGFR-IN-1Osimertinib analog；AZD9291中间体1

    Mutated EGFR-IN-1 is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.

    价 格：￥电议型 号：T16162产 地：中国大陆

  • T1510Rosuvastatin calcium瑞舒伐他汀钙；Rosuvastatin hemicalcium；ZD4522；ZD 4522 Calcium

    Rosuvastatin, a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity.

    价 格：￥电议型 号：T1510产 地：中国大陆

  • T14388AZD 4017

    AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).

    价 格：￥电议型 号：T14388产 地：中国大陆

  • T14385AZD9056 hydrochloride

    AZD9056 hydrochloride is a P2X7 inhibitor，Which plays a significant role in pain-causing diseases and inflammation.

    价 格：￥电议型 号：T14385产 地：中国大陆

  • T14381AZD7624AZD-7624

    AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.

    价 格：￥电议型 号：T14381产 地：中国大陆

  • T14380AZD7507

    AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.

    价 格：￥电议型 号：T14380产 地：中国大陆

  • T14379AZD5904

    AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO, IC50: 140 nM) which has similar potency in mouse and rat.

    价 格：￥电议型 号：T14379产 地：中国大陆

  • T14378LAZD5582 acetate (1258392-53-8 free base)

    AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively. AZD5582 induces apoptosis.

    价 格：￥电议型 号：T14378L产 地：中国大陆

  • T14377AZD5423

    AZD5423 is an inhaled, potent, selective, and non-steroidal modulator of glucocorticoid receptor (GR) and it effectively reduces allergen-induced responses in subjects with mild allergic asthma.

    价 格：￥电议型 号：T14377产 地：中国大陆

  • T14376AZD4320

    AZD4320 is an inhibitor of BH3-mimicking dual BCL2/BCLxL. For KPUM-MS3, KPUM-UH1, and STR-428 cells, the IC50s values are 26 nM, 17 nM, and 170 nM , respectively.

    价 格：￥电议型 号：T14376产 地：中国大陆

  • T14369AZD-0284

    AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].

    价 格：￥电议型 号：T14369产 地：中国大陆

  • T1416Zidovudine齐多夫定；叠氮胸苷；AZT；Azidothymidine；ZDV；NSC 602670

    Zidovudine is a synthetic dideoxynucleoside. After intracellular phosphorylation to its active metabolite, zidovudine inhibits DNA polymerase, resulting in the inhibition of DNA replication and cell death. This agent also decreases levels of available pyr

    价 格：￥电议型 号：T1416产 地：中国大陆

  • T1181GefitinibZD1839；吉非替尼

    Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM).

    价 格：￥电议型 号：T1181产 地：中国大陆

  • T10435Linaprazan利那拉生；AZD0865

    Linaprazan inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.

    价 格：￥电议型 号：T10435产 地：中国大陆

  • T10433Osimertinib dimesylate奥希替尼二甲磺酸盐；AZD-9291 (dimesylate)；Mereletinib (dimesylate)

    Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).

    价 格：￥电议型 号：T10433产 地：中国大陆

  • T10432LAZD-8529 mesylate

    AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM). It shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.

    价 格：￥电议型 号：T10432L产 地：中国大陆

  • T10431GolidocitinibAZD4205

    AZD4205 is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).

    价 格：￥电议型 号：T10431产 地：中国大陆

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