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  • T14379AZD5904AZD5904

    AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM. Which has similar potency in mouse and rat.

    价 格:¥电议型 号:T14379产 地:美洲

  • T14380AZD7507AZD7507

    AZD7507 is a CSF-1R inhibitor. It has antitumor activity.

    价 格:¥电议型 号:T14380产 地:美洲

  • T14382AZD7687AZD7687

    AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). IC50 value: 80 nM [1] Target: DGAT1 in vitro: Plasma AZD7687 exposure was measured repeatedly. AZD7687 markedly reduced postprandial TAG excursion with a steep concent

    价 格:¥电议型 号:T14382产 地:美洲

  • T14383AZD8329AZD8329

    AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1. Which displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3[1].

    价 格:¥电议型 号:T14383产 地:美洲

  • T14384AZD8797AZD8797

    AZD8797 is an allosteric non-competitive modulator of the human CX3CR1 receptor. For antagonizes CX3CR1 and CXCR2, the Kis values are 3.9 and 2800 nM, respectively.

    价 格:¥电议型 号:T14384产 地:美洲

  • T14385AZD9056 hydrochlorideAZD9056 hydrochloride

    AZD9056 hydrochloride is a P2X7 inhibitor. Which plays a significant role in pain-causing diseases and inflammation.

    价 格:¥电议型 号:T14385产 地:美洲

  • T14386AZD9567AZD9567

    AZD9567 (compound 15) is a potent, oral active, non-steroidal and selective glucocorticoid receptor modulator (SGRM), with an IC50 of 3.8 nM. It shows excellent efficacy in the streptococcal cell wall (SCW) reactivation model of joint inflammation[1].

    价 格:¥电议型 号:T14386产 地:美洲

  • T1510Rosuvastatin calciumRosuvastatin calcium,ZD 4522 Calcium,Rosuvastatin hemicalcium

    Rosuvastatin, a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity.

    价 格:¥电议型 号:T1510产 地:美洲

  • T15706LanicemineLanicemine,AZD6765,

    Lanicemine is a low-trapping NMDA channel blocker. It also has a binding (Ki: 0.56-2.1?μM).

    价 格:¥电议型 号:T15706产 地:美洲

  • T16114PavinetantPavinetant,MLE-4901,AZD2624

    Pavinetant is an antagonist of the neurokinin-3 receptor (NK3R).

    价 格:¥电议型 号:T16114产 地:美洲

  • T1656VandetanibVandetanib,ZD6474,

    Vandetanib is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.

    价 格:¥电议型 号:T1656产 地:美洲

  • T16699PYZD-4409PYZD-4409

    PYZD-4409 causes cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells. PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 (IC50: 20 μM (cell-free enzymatic assay)).

    价 格:¥电议型 号:T16699产 地:美洲

  • T1676RosuvastatinRosuvastatin,ZD 4522,

    Rosuvastatin is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Rosuvastat

    价 格:¥电议型 号:T1676产 地:美洲

  • T1741AZD1080AZD1080

    AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.

    价 格:¥电议型 号:T1741产 地:美洲

  • T1836AZD2932AZD2932

    AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.

    价 格:¥电议型 号:T1836产 地:美洲

  • T1859AZD8055AZD8055

    AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.

    价 格:¥电议型 号:T1859产 地:美洲

  • T1920CapivasertibCapivasertib,AZD5363,

    Capivasertib (AZD5363) is a new-type orally available inhibitor of the serine/threonine protein kinase AKT (IC50s: 3/7/7 nM for Akt1/2/3).

    价 格:¥电议型 号:T1920产 地:美洲

  • T1948AZD4547AZD4547

    AZD4547, a new-type specific FGFR inhibitor, targets for FGFR1/2/3 (IC50: 0.2/2.5/1.8 nM in cell-free assays).

    价 格:¥电议型 号:T1948产 地:美洲

  • T1957AZD2858AZD2858

    AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.

    价 格:¥电议型 号:T1957产 地:美洲

  • T1961VistusertibVistusertib,AZD2014,

    AZD2014 is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.

    价 格:¥电议型 号:T1961产 地:美洲

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