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T6399AZD1981AZD1981
AZD1981 is an effective and specific CRTh2 (DP2) receptor antagonist (IC50: 4 nM), showing >1000-fold selectivity over more than 340 other enzymes and receptors, including DP1. AZD1981 has been used in trials studying the treatment and basic science of As
价 格:¥电议型 号:T6399产 地:美洲
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T6400AZD3514AZD3514
AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.
价 格:¥电议型 号:T6400产 地:美洲
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T8751AZD8931 diFuMaric acid化合物AZD8931 diFuMaric acid4-[[4-[(3-氯-2-氟苯基)氨基]-7-甲氧基-6-喹唑啉基]氧基]-N-甲基-1-哌啶乙酰胺二富
AZD8931 is a reversible and ATP competitive inhibitor of EGFR, ErbB2 and ErbB3 (IC50 of 4 nM, 3 nM and 4 nM, respectively).
价 格:¥电议型 号:T8751产 地:中国大陆
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T82607Dazdotuftide;化合物 DazdotuftideTRS01;TRS01
Dazdotuftide is an active immunomodulatory compound [1].
价 格:¥电议型 号:T82607产 地:中国大陆
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T80079Mazdutide TFA;化合物 Mazdutide TFALY-3305677 TFA|||IBI-362 TFA|||OXM-3 TFA;LY-3305677 TFA|||IBI-362 TFA
Mazdutide (IBI-362; LY-3305677) TFA is a dual agonist for the glucagon-like peptide-1 receptor (GLP-1R) and the glucagon receptor (GCGR), also recognized as a long-acting synthetic oxyntomodulin analog. It demonstrates a favorable safety and tolerability profile, and is utilized in research related to obesity and type 2 diabetes (T2D) [1] [2].
价 格:¥电议型 号:T80079产 地:中国大陆
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T79297DZD1516;化合物 DZD1516DZD1516
DZD1516, a potent and selective HER2 inhibitor (IC50 = 0.56 nM), demonstrates good blood-brain barrier permeability and exhibits antitumor activity in both central nervous system (CNS) and subcutaneous xenograft mouse models [1].
价 格:¥电议型 号:T79297产 地:中国大陆
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T79213AZD4747;化合物AZD4747AZD4747
AZD4747 is a selective and potent inhibitor of the mutant GTPase KRASG12C that crosses the blood-brain barrier and has potential antitumor activity for the study of pancreatic and colorectal adenocarcinoma.
价 格:¥电议型 号:T79213产 地:中国大陆
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T78097LMazdutide acetate(2259884-03-0 free base);化合物 Mazdutide acetate(2259884-03-0 free base)Mazdutide ace
Mazdutide acetate is a potent co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR), a gastrin-regulating hormone analog.Mazdutide acetate stimulates insulin secretion from mouse pancreatic islets, and can be used in studies of obesity and type 2 diabetes (T2D).
价 格:¥电议型 号:T78097L产 地:中国大陆
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T78097Mazdutide;化合物 MazdutideIBI-362|||LY-3305677|||OXM-3;IBI-362|||LY-3305677|||OXM-3
Mazdutide (IBI-362; LY-3305677), a synthetic oxyntomodulin analog, serves as a glucagon-like peptide-1 (GLP-1R)/glucagon receptor (GCGR) co-agonist. Demonstrating safety and tolerability, Mazdutide is utilized in obesity and type 2 diabetes (T2D) research [1] [2].
价 格:¥电议型 号:T78097产 地:中国大陆
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T77985AZD9496 deacrylic acid phenol;化合物 AZD9496 deacrylic acid phenolAZD9496 deacrylic acid phenol
AZD9496 deacrylic acid phenol (AZD9496) represents a portion of the ligand that targets the protein for PROTAC ER Degrader-4 [1].
价 格:¥电议型 号:T77985产 地:中国大陆
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T7699AZD7325;化合物AZD-7325AZD-7325;AZD-7325
AZD7325 (AZD-7325) is a GABA-Aα2,3 -selective receptor modulator.
价 格:¥电议型 号:T7699产 地:中国大陆
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T7681AZD-5069;化合物AZD-5069AZD-5069
AZD-5069 is an chemokine receptor 2 antagonist (CXCR2; IC50 = 0.79 nM).
价 格:¥电议型 号:T7681产 地:中国大陆
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T7587LTenapanor HCl;化合物 T7587LRDX-5791|||AZD 1722|||AZD-1722|||AZD1722|||RDX5791|||RDX 5791;RDX-5791|||AZD
Tenapanor( AZD-1722, RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which is used for sodium handling in the gastrointestinal tract and kidney.
价 格:¥电议型 号:T7587L产 地:中国大陆
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T7587Tenapanor;化合物TenapanorRDX-5791|||RDX 5791|||AZD 1722|||Tenapanor free base|||RDX5791|||AZD-1722|||AZ
Tenapanor (RDX 5791) is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects.
价 格:¥电议型 号:T7587产 地:中国大陆
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T7516ZD7288;化合物ZD7288ICI D7288;N-乙基-1,6-二氢-1,2-二甲基-6-(甲基亚氨基)-N-苯基-4-嘧啶胺盐酸盐|||ICI D7288
ZD7288 (ICI D7288), a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity.
价 格:¥电议型 号:T7516产 地:中国大陆
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T74395Dicloromezotiaz;化合物 DicloromezotiazDicloromezotiaz
Dicloromezotiaz, a potent insecticide, targets nicotinic acetylcholine receptors (nAChRs) to control a broad spectrum of lepidoptera [1].
价 格:¥电议型 号:T74395产 地:中国大陆
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T74143AZD4694 Precursor;化合物 AZD4694 PrecursorAZD4694 Precursor
AZD4694 Precursor (AZ13040214) serves as the foundational compound for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging ligand targeting amyloid-β plaques [1].
价 格:¥电议型 号:T74143产 地:中国大陆
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T72515Elobixibat hydrate;化合物 Elobixibat hydrateA 3309 hydrate ; AZD 7806 hydrate|||AZD 7806 hydrate|||A 3
Elobixibat hydrate, a potent inhibitor of the ileal bile acid transporter (IBAT), exhibits IC50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human, mouse, and canine IBAT, respectively. It is utilized in the research of chronic idiopathic constipation (CIC).
价 格:¥电议型 号:T72515产 地:中国大陆
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T72215Lesogaberan hydrochloride;Lesogaberan hydrochlorideAZD-3355 hydrochloride;AZD-3355 hydrochloride
Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABA B receptor agonist with an EC 50 of 8.6 nM for human recombinant GABA B receptor. The affinity ( K i s) of Lesogaberan hydrochloride for rat GABA B and GABA A receptors, as measured by displacement of [ 3 H]GABA binding in brain membranes: 5.1 nM and 1.4 μM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action [1] .
价 格:¥电议型 号:T72215产 地:中国大陆
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T71894AZD3229 Tosylate;化合物 AZD3229 TosylateAZD3229 Tosylate
AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinal stromal tumors (GISTs).
价 格:¥电议型 号:T71894产 地:中国大陆