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T80976TLR7/8 agonist 4 hydroxy-PEG6-acid;化合物 TLR7/8 agonist 4 hydroxy-PEG6-acidTLR7/8 agonist 4 hydroxy-PE
TLR7/8 agonist 4 hydroxy-PEG6-acid, a Drug-Linker Conjugate for ADCs, comprises the TLR7/8 agonist 4 and a hydroxy-PEG6-acid linker, suitable for the synthesis of antibody-drug conjugates (ADCs) [1].
价 格:¥电议型 号:T80976产 地:中国大陆
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T80975TMDJ-035;化合物 TMDJ-035TMDJ-035
TMDJ-035 is a selective inhibitor of the RyR2 (ryanodine receptor 2). It effectively suppresses abnormal calcium (Ca^2+) waves and transients in isolated cardiomyocytes derived from mice with RyR2 mutations. As such, TMDJ-035 serves as a valuable tool in research for elucidating the gating mechanisms and dynamics of the RyR2 channel [1].
价 格:¥电议型 号:T80975产 地:中国大陆
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T80974TMX-4153;化合物 TMX-4153TMX-4153
TMX-4153 is a bivalent degrader that selectively targets and rapidly degrades endogenous PIP4K2C through recruitment of the von Hippel-Lindau (VHL) E3 ligase complex, demonstrating a K D of 42 nM. It is applicable in the synthesis of PROTAC [1].
价 格:¥电议型 号:T80974产 地:中国大陆
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T80973TNF-α-IN-8;化合物 TNF-α-IN-8TNF-α-IN-8
TNF-α-IN-8 (compound I-42) is an isoindole-imide-based inhibitor of tumor necrosis factor-alpha (TNF-α) with applications in researching various diseases including cancer, heart disease, osteoporosis, and autoimmune disorders. Additionally, this compound serves as a click chemistry reagent, possessing an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) or strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Alkyne, DBCO, or BCN group
价 格:¥电议型 号:T80973产 地:中国大陆
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T80972TNH;化合物 TNHTMP-NVOC linker-Halo;TMP-NVOC linker-Halo
TNH, a dimeric compound, possesses the ability to penetrate living cells and facilitate the recruitment of proteins into cellular structures [1].
价 格:¥电议型 号:T80972产 地:中国大陆
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T80971TNIK-IN-6;化合物 TNIK-IN-6TNIK-IN-6
TNIK-IN-6 (Compound 9) acts as an inhibitor of Traf2 and Nck-interacting kinase (TNIK), exhibiting an inhibitory concentration (IC50) of 0.93 μM, a kinase implicated in various neurological and psychiatric disorders [1] [2].
价 格:¥电议型 号:T80971产 地:中国大陆
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T80970Tobevibart;化合物 TobevibartTobevibart
Tobevibart, an IgG1-lambda humanized monoclonal antibody targeting the hepatitis B virus (HBV) surface envelope protein, exhibits antiviral activity [1].
价 格:¥电议型 号:T80970产 地:中国大陆
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T8097Methyl 3-aminopropanoate hydrochloride;3-氨基丙酸甲酯盐酸盐β-Alanine methyl ester hydrochloride;β-Alanine met
Methyl 3-aminopropanoate hydrochloride (β-Alanine methyl ester hydrochloride) is the ethyl ester of the non-essential amino acid β-alanine.
价 格:¥电议型 号:T8097产 地:中国大陆
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T80097Hirullin P18;化合物 Hirullin P18Hirullin P18
Hirullin P18 is a potent thrombin inhibitor with anticoagulant properties [1].
价 格:¥电议型 号:T80097产 地:中国大陆
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T79097PROTAC IRAK4 degrader-8;化合物 PROTAC IRAK4 degrader-8PROTAC IRAK4 degrader-8
PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].
价 格:¥电议型 号:T79097产 地:中国大陆
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T78097LMazdutide acetate(2259884-03-0 free base);化合物 Mazdutide acetate(2259884-03-0 free base)Mazdutide ace
Mazdutide acetate is a potent co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR), a gastrin-regulating hormone analog.Mazdutide acetate stimulates insulin secretion from mouse pancreatic islets, and can be used in studies of obesity and type 2 diabetes (T2D).
价 格:¥电议型 号:T78097L产 地:中国大陆
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T78097Mazdutide;化合物 MazdutideIBI-362|||LY-3305677|||OXM-3;IBI-362|||LY-3305677|||OXM-3
Mazdutide (IBI-362; LY-3305677), a synthetic oxyntomodulin analog, serves as a glucagon-like peptide-1 (GLP-1R)/glucagon receptor (GCGR) co-agonist. Demonstrating safety and tolerability, Mazdutide is utilized in obesity and type 2 diabetes (T2D) research [1] [2].
价 格:¥电议型 号:T78097产 地:中国大陆
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T77097Nerelimomab;化合物 NerelimomabNerelimomab
Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].
价 格:¥电议型 号:T77097产 地:中国大陆
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T76097Aldolase;化合物 AldolaseAldolase
Aldolase, a glycolytic enzyme and component of the VATPase complex, catalyzes the decomposition of fructose 1,6-diphosphate into dihydroxyacetone and glyceraldehyde 3-phosphate [1].
价 格:¥电议型 号:T76097产 地:中国大陆
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T7550Barnidipine;化合物BarnidipineYM-09730-5(Free base)|||Mepirodipine;YM-09730-5(Free base)|||(4S)-2,6-二甲基-
Barnidipine (YM-09730-5(Free base)) is a calcium channel blocker.
价 格:¥电议型 号:T7550产 地:中国大陆
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T75097STING agonist-29;化合物 STING agonist-29STING agonist-29
STING agonist-29 (CF511) is a non-nucleotide small-molecule compound that acts as a STING agonist, effectively activating STING and demonstrating activity against SARS-CoV series strains [1].
价 格:¥电议型 号:T75097产 地:中国大陆
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T74097THX-B;化合物 THX-BTHX-B
THX-B, a potent non-peptidic antagonist of the neurotrophin receptor p75 (p75 NTR), is utilized in the study of diabetic kidney disease, neurodegenerative, and inflammatory disorders [1] [2] [3].
价 格:¥电议型 号:T74097产 地:中国大陆
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T73097SID-852843;化合物SID-852843SID-852843
SID-852843 is a WNV NS2B-NS3 protease inhibitor with an IC50 value of 0.105 μM for WNV NS2B-NS3 protease.SID-852843 can be used for the study of viral infections.
价 格:¥电议型 号:T73097产 地:中国大陆
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T72097Eleven-Nineteen-Leukemia Protein IN-2;化合物 Eleven-Nineteen-Leukemia Protein IN-2Eleven-Nineteen-Leuke
Eleven-Nineteen-Leukemia Protein IN-2 (compound 23), an ENL inhibitor, exhibits an IC50 of 10.7 nM and is utilized for leukemia research [1].
价 格:¥电议型 号:T72097产 地:中国大陆
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T7184Firsocostat;化合物ND-630ND-630|||NDI-010976|||GS-0976;ND-630|||NDI-010976|||GS-0976
Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
价 格:¥电议型 号:T7184产 地:中国大陆