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T6398Azaperone阿扎哌隆R-1929|||Fluoperidol|||阿扎哌隆|||Stresnil|||NSC 170976|||Suicalm
Azaperone (Fluoperidol) is a pyridinylpiperazine and butyrophenone neuroleptic drug with sedative and antiemetic effects, which is used mainly as a tranquilizer in veterinary medicine.
价 格:¥电议型 号:T6398产 地:中国大陆
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T63903BPR1J-097 Hydrochloride;化合物 BPR1J-097 HydrochlorideBPR1J-097 Hydrochloride
BPR1J-097 Hydrochloride is a novel, potent FLT3 inhibitor (IC50: 11 nM).
价 格:¥电议型 号:T63903产 地:中国大陆
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T63097Taragarestrant;化合物 TaragarestrantTaragarestrant
Taragarestrant (D-0502) is an orally active estrogen receptor degrader with anticancer activity. taragarestrant exhibits anti-proliferative effects on estrogen receptor positive breast cancer cell lines. taragarestrant can be used in cancer research.
价 格:¥电议型 号:T63097产 地:中国大陆
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T6274RO4929097;化合物RO4929097RG-4733;RG-4733
RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).
价 格:¥电议型 号:T6274产 地:中国大陆
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T62097UNC10201652;化合物 UNC10201652UNC10201652
UNC10201652 is a potent inhibitor of L1-specific intestinal bacterial β-glucuronidases (GUSs) and is able to act on Escherichia coli (E. coli) (IC50: 0.117 μM). glucuronide processing.
价 格:¥电议型 号:T62097产 地:中国大陆
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T61097Anticancer agent 70;化合物 Anticancer agent 70Anticancer agent 70
Anticancer agent 70 (Compound 21) is a potent anticancer compound that demonstrates remarkable cytotoxicity against multiple human cancer cell lines. It induces G0/G1-cell cycle arrest and concurrently elevates the levels of p53 and p21 proteins. Furthermore, Anticancer agent 70 induces ATP depletion and disruption of the mitochondrial membrane potential [1].
价 格:¥电议型 号:T61097产 地:中国大陆
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T60979Oxaprozin potassium;化合物 Oxaprozin potassiumOxaprozin potassium
Oxaprozin potassium is an orally active and potent inhibitor of COX, with IC 50 values of 2.2 μM and 36 μM for human platelet COX-1 and for IL-1-stimulated human synovial cell COX-2, respectively. Oxaprozin potassium induces cell apoptosis. Oxaprozin potassium also inhibits the NF-κB activation. Oxaprozin potassium-mediated inhibition of the Akt/IKK/NF-κB pathway contributes to its anti-inflammatory properties [1] [2].
价 格:¥电议型 号:T60979产 地:中国大陆
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T60978COX-2-IN-7;化合物 COX-2-IN-7COX-2-IN-7
COX-2-IN-7 (compound 4a) is a potent, selective, and orally active COX-2 inhibitor which is higher selectivity than Celecoxib with an IC 50 value of 6.585 uM. COX-2-IN-7 has good anti-inflammatory and low ulcerogenic activity in vivo[1].
价 格:¥电议型 号:T60978产 地:中国大陆
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T60977TL8-506;化合物 TL8-506TL8-506
TL8-506 can be used in autoimmune diseases and tuberculosis research which is a specific agonist of TLR8 (EC 50 = 30 nM) [1].
价 格:¥电议型 号:T60977产 地:中国大陆
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T60976Bezuclastinib;化合物BezuclastinibCGT9486|||PLX 9486;CGT9486|||PLX 9486
Bezuclastinib (CGT9486) is a novel, potent and highly selective tyrosine kinase and c-kit D816V inhibitor for the study of advanced mastocytosis.
价 格:¥电议型 号:T60976产 地:中国大陆
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T60975Antitumor agent-50;化合物 Antitumor agent-50Antitumor agent-50
Antitumor agent-50 (compound 1a) is a thiazolidinone. Antitumor agent-50 is an effective antitumor agent that has the potential for the research of osteosarcoma (OS) [1].
价 格:¥电议型 号:T60975产 地:中国大陆
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T60974MetRS-IN-1;化合物 MetRS-IN-1MetRS-IN-1
MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].
价 格:¥电议型 号:T60974产 地:中国大陆
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T60973HPK1-IN-24;化合物 HPK1-IN-24HPK1-IN-24
HPK1-IN-24 (example 51) has potential to be used in the cancer research which is an inhibitor of hematopoietic progenitor kinase 1 (HPK1) (Ki = 100 nM) [1].
价 格:¥电议型 号:T60973产 地:中国大陆
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T60972Pim-1 kinase inhibitor 1;化合物 Pim-1 kinase inhibitor 1Pim-1 kinase inhibitor 1
Pim-1 kinase inhibitor 1 can be used in cancer research, showing anticancer activity against a variety of cancer cell lines by promoting cell apoptosis. Pim-1 kinase inhibitor 1 is an inhibitor of Pim-1 kinase with an IC 50 value of 0.11 μM [1].
价 格:¥电议型 号:T60972产 地:中国大陆
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T60971Antitubercular agent-14;化合物 Antitubercular agent-14Antitubercular agent-14
Antitubercular agent-14 (Compound 1) shows antitubercular activity. The MIC value of Antitubercular agent-14 against M. tuberculosis is 0.3 μg/mL [1].
价 格:¥电议型 号:T60971产 地:中国大陆
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T60970Caprochlorone;化合物 CaprochloroneCaprochlorone
Caprochlorone exhibits antiviral activity against orthopoxvirus that decreases the influenza virus titers in infected-mice lungs. Caprochlorone can inhibit cell penetration by virus as well as delays newly formed virus release from the cell [1] [2] [3].
价 格:¥电议型 号:T60970产 地:中国大陆
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T6097GNF-5837;化合物GNF5837GNF 5837;GNF 5837
GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).
价 格:¥电议型 号:T6097产 地:中国大陆
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T60517CL097 hydrochloride;化合物 CL097 hydrochlorideCL097 hydrochloride
CL097 hydrochloride is a potent TLR7 and TLR8 agonist. CL097 hydrochloride induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-stimulated ROS production [2].
价 格:¥电议型 号:T60517产 地:中国大陆
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T60097Methyl (E)-sinapate;芥子酸甲酯Methyl (E)-sinapate
Methyl (E)-sinapate is isolated from the Polygala sibirica L.var. megalopha Fr.
价 格:¥电议型 号:T60097产 地:中国大陆
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T5S1097Neferine甲基莲心碱(R)-1,2-Dimethoxyaporphine|||(-)-Neferine|||甲基莲心碱
1. Neferine ((-)-Neferine) has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase the efficacy of DOX and to achieve anticancer synergism by curbing the toxicity. 3. Neferine inhibited high glucose-induced endothelial apoptosis via blocking ROS/Akt/NF-κB pathway, which provides the evidence for using Neferine to treat diabetic vasculopathy. 4. Neferine induced apoptosis in a dose-depende
价 格:¥电议型 号:T5S1097产 地:中国大陆