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  • T71097DC-120；化合物 DC-120DC-120

    DC-120 is an ATP competitive AKT kinase inhibitor that suppressed proliferation and induced apoptosis in liver cancer cells both in vitro and in vivo. DC120 blocked the phosphorylation of downstream molecules in the AKT signal pathway in dose- and time-dependent manners both in vitro and in vivo. DC120 inhibits AKT activity in vitro with an EC(50) of 153 nM. DC120 at 20 mg/kg/day inhibited the CNE2 xenograft tumor growth with a treated group/control group ratio of 38.1%, accompanied by increas

    价 格：￥电议型 号：T71097产 地：中国大陆

  • T70979Sunepitron Free Base；化合物 Sunepitron Free BaseSunepitron Free Base

    Sunepitron Free Base is a combined 5-HT1A receptor agonist and α?-adrenergic receptor antagonist. It was previously under development by Pfizer for the treatment of depression and anxiety. It made it to phase III clinical trials before being discontinued.

    价 格：￥电议型 号：T70979产 地：中国大陆

  • T709785-Hydroxy Lansoprazole Sulfide；化合物 5-Hydroxy Lansoprazole Sulfide5-Hydroxy Lansoprazole Sulfide

    5-Hydroxy Lansoprazole Sulfide is an inhibitor of fatty acid synthase (FASN). FASN, which is responsible for de-novo synthesis of lipids, has been found to be overexpressed in cancerous tissue. 5-Hydroxy Lansoprazole Sulfide specifically inhibits enoyl reductase, and was found to more effectively inhibit FASN function than lansoprazole and was also more efficient at regulating NHEJ repair of oxidative DNA damage via PARP1.

    价 格：￥电议型 号：T70978产 地：中国大陆

  • T70977JMN13497；化合物 JMN13497JMN13497

    JMN13497 is an precursor compound to for synthesis of scytonemin. Scytonemin is a biological pigment synthesized by many strains of cyanobacteria, including Calothrix sp., Lyngbya aestuarii, and others. Scytonemin is also a potent PKL1 inhibitor, which inhibits cell proliferation and arrests cell cycle through downregulating Plk1 activity in many cancel cells. Scytonemin was able to inhibit the proliferation of three myeloma cells in a dose-dependent manner, while U266 was the most sensitive on

    价 格：￥电议型 号：T70977产 地：中国大陆

  • T70976AGN-190121；化合物 AGN-190121AGN-190121

    AGN-190121 is a retinoic acid receptor (RAR) agonist. RAR and Retinoid X Receptor (RXR) ligands can act synergistically to induce hypertriglyceridemia through distinct mechanisms of action.

    价 格：￥电议型 号：T70976产 地：中国大陆

  • T70975Carsatrin succinate；化合物 Carsatrin succinateCarsatrin succinate

    Carsatrin succinate is the salt form of Carsatin, a purinylpiperazine derivative used as a cardiotonic and antiarrhythmic. Carsatrin acts as positive inotropic agent that increases twitch tension and prolongs the action potential (AP) duration of ventricular muscle without affecting the Na+, K+-ATPase, adenylyl cyclase, phosphodiesterase isozymes, or cardiac myofilaments. Carsatrin’s positive inotropic effect can be prevented by tetrodotoxin but not by the adrenergic antagonists timolol, yohimbi

    价 格：￥电议型 号：T70975产 地：中国大陆

  • T70974Cipamfylline；化合物 CipamfyllineCipamfylline

    Cipamfylline is a xanthine, a theophylline analogue, and is a potent and selective inhibitor of phosphodiesterase type 4 (PDE-4). Cipamfylline was tested in patients with a diagnosis of atopic dermatitis and in two human models of acute and chronic irritant contact dermatitis. The outcome of the study revealed that cipamfylline was more effective than vehicle in treating atopic dermatitis, but less effective than a group II steroid, hydrocortisone-17-butyrate both in the treatment of atopic derm

    价 格：￥电议型 号：T70974产 地：中国大陆

  • T70973Zifrosilone；化合物 ZifrosiloneZifrosilone

    Zifrosilone is an acetylcholinesterase inhibitor.

    价 格：￥电议型 号：T70973产 地：中国大陆

  • T70972RP 59794；化合物 RP 59794RP 59794

    RP 59794 is a collagenase inhibitor.

    价 格：￥电议型 号：T70972产 地：中国大陆

  • T70971VGD020；化合物 VGD020VGD020

    VGD020 is a CD4 and sortilin inhibitor. It displayed activity for sortilin down-modulation and reduction of progranulin-induced breast cancer stem cell propagation.

    价 格：￥电议型 号：T70971产 地：中国大陆

  • T70970Khl 8430；化合物 Khl 8430Khl 8430

    Khl 8430 is a potent and specific inhibitor of calmodulin activity.

    价 格：￥电议型 号：T70970产 地：中国大陆

  • T7097Cytochalasin B；细胞松弛素BPhomin；Phomin|||细胞松弛素 B|||细胞松弛素B

    Cytochalasin B is a mycotoxin binding to the barbed end of actin filaments. It can disrupt the formation of actin polymers (Kd: 1.4-2.2 nM for F-actin).

    价 格：￥电议型 号：T7097产 地：中国大陆

  • T70097Acefylline piperazine；化合物 Acefylline piperazineAcefylline piperazine

    Acefylline piperazine is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. Acephylline piperazine is a theophylline derivative with a direct bronchodilator action. It has the advantages over theophylline in being far less toxic and producing minimal gastric irritation. It is indicated for the treatment of asthma, emphysema, acute and chronic bronchitis associated with bronchospasm.Acefylline relaxes smooth muscles, relieves bronchospasm & has a stimula

    价 格：￥电议型 号：T70097产 地：中国大陆

  • T69643DGY-08-097；化合物 DGY-08-097DGY-08-097

    DGY-08-097 is a novel HCV NS3 degrader, reducing susceptibility to resistance mutations, potently inhibiting HCV in a cellular infection model, exhibiting the most potent degradation (DC50 of 50nM at 4h) of HCV NS3.

    价 格：￥电议型 号：T69643产 地：中国大陆

  • T69097ARD-353；化合物 ARD-353ARD-353

    ARD-353 is a nonpeptide delta receptor agonist with cardioprotective effects.

    价 格：￥电议型 号：T69097产 地：中国大陆

  • T68097Mequitamium；甲喹碘铵Mequitamium

    Mequitamium is a potent pharmaceutical intermediate for the synthesis of Mequitazium iodide.

    价 格：￥电议型 号：T68097产 地：中国大陆

  • T6709716alpha-Hydroxyprednisonlone acetate；化合物 16alpha-Hydroxyprednisonlone acetate16alpha-Hydroxypredniso

    16alpha-Hydroxyprednisonlone acetate is a useful organic compound for research related to life sciences. The catalog number is T67097 and the CAS number is 86401-80-1.

    价 格：￥电议型 号：T67097产 地：中国大陆

  • T66097Ethyl 4-bromocrotonate4-溴巴豆酸乙酯(E)-Ethyl 4-bromobut-2-enoate

    Ethyl 4-bromocrotonate ((E)-Ethyl 4-bromobut-2-enoate) is an antimicrobial compound belonging to the ester group. As an important pharmaceutical intermediate, it has been used as a substrate for enzyme-catalyzed reactions, and as a tool for studying enzyme kinetics. It has also been found to have anti-inflammatory and analgesic properties.

    价 格：￥电议型 号：T66097产 地：中国大陆

  • T65097(2R,3R,4R,5R)-4-(((2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-trihyd

    (2R,3R,4R,5R)-4-(((2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-2,3,5,6-tetrahydroxyhexanal is a natural product for research related to life sciences. The catalog number is T65097 and the CAS number is 33404-34-1.

    价 格：￥电议型 号：T65097产 地：中国大陆

  • T64097KRAS G12C inhibitor 21；化合物 KRAS G12C inhibitor 21KRAS G12C inhibitor 21

    KRAS G12C inhibitor 21 is a KRAS G12C inhibitor.

    价 格：￥电议型 号：T64097产 地：中国大陆

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