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  • T82394FLAG-Cys;化合物 FLAG-CysFLAG-Cys

    FLAG-Cys is a Flag peptide modified by the addition of a cysteine (Cys) residue, known to exhibit immunogenicity [1].

    价 格:¥电议型 号:T82394产 地:中国大陆

  • T82393FLT3/CHK1-IN-1;化合物 FLT3/CHK1-IN-1FLT3/CHK1-IN-1

    Compound 18, also known as FLT3/CHK-IN-1, is a dual inhibitor targeting FLT3 and CHK1, exhibiting over 1700-fold selectivity towards c-KIT and significantly diminishing hERG affinity, with an IC50 of 58.4 μM. It demonstrates efficacy in suppressing tumor growth in mouse xenotransplantation models implanted with MV-4-11 cells [1].

    价 格:¥电议型 号:T82393产 地:中国大陆

  • T82392FLT3-IN-23;化合物 FLT3-IN-23FLT3-IN-23

    FLT3-IN-23 (compound 15), a potent inhibitor of FMS-like tyrosine kinase 3 (FLT3), exhibits an IC 50 value of 7.42 nM and demonstrates antiproliferative effects against BaF3 cells harboring diverse FLT3-TKD and FLT3-ITD-TKD mutations [1].

    价 格:¥电议型 号:T82392产 地:中国大陆

  • T82391Fluo-3;化合物 Fluo-3Fluo-3

    Fluo-3 and its derivative, Fluo3/AM, serve as fluorescent indicators for intracellular calcium (Ca2+), facilitating detection through flow cytometry and confocal laser scanning microscopy with visible light excitation (compatible with argon laser sources at 488 nm). Upon binding to calcium, these compounds exhibit a fluorescence intensity increase of approximately 40-fold.

    价 格:¥电议型 号:T82391产 地:中国大陆

  • T82390Fluorescein hydrazide;化合物 Fluorescein hydrazideFluorescein hydrazide

    Fluorescein hydrazide, a colorimetric probe synthesized through the reaction of dihydrazine adipate with fluorescein isothiocyanate, serves to label aldehyde and ketone groups [1] [2].

    价 格:¥电议型 号:T82390产 地:中国大陆

  • T8239Cromoglicic acid;色甘酸Cromoglicic acid

    Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.

    价 格:¥电议型 号:T8239产 地:中国大陆

  • T82239HAP-1;化合物 HAP-1HAP-1

    HAP-1, a synovial-targeted transduction peptide, selectively mediates the internalization of protein complexes into synovial cells of human and rabbit origin. When fused with the antimicrobial peptide (KLAK)2, HAP-1 forms the proapoptotic peptide DP2 [1].

    价 格:¥电议型 号:T82239产 地:中国大陆

  • T82158Human IgG1 (S239D/I332E) kappa, Isotype Control;化合物 Human IgG1 (S239D/I332E) kappa, Isotype ControlH

    Human IgG1 (S239D/I332E) kappa Isotype Control is a chimeric monoclonal antibody derived from human and mouse sequences, serving as an isotype control for the Human IgG1 (S239D/I332E)κ antibody.

    价 格:¥电议型 号:T82158产 地:中国大陆

  • T81239RXFP1 receptor agonist-8;化合物 RXFP1 receptor agonist-8RXFP1 receptor agonist-8

    Example 2 (RXFP1 receptor agonist-8) is a potent RXFP1 receptor agonist that suppresses cAMP production in HEK293 cells expressing human RXFP1, exhibiting an EC50 of 1.8 nM [1].

    价 格:¥电议型 号:T81239产 地:中国大陆

  • T80239TFLLRNPNDK-NH2;化合物 TFLLRNPNDK-NH2TFLLRNPNDK-NH2

    TFLLRNPNDK-NH2 is a biologically active peptide and a thrombin receptor activating peptide (TRAP). As a PAR-1 agonist, it reversibly binds to PAR-1, mimicking the ´tethered ligand´ created by thrombin through proteolytic substrate cleavage. It also induces increased liquid and protein permeability, similar to thrombin´s effect.

    价 格:¥电议型 号:T80239产 地:中国大陆

  • T79239PCSK9-IN-19;化合物 PCSK9-IN-19PCSK9-IN-19

    PCSK9-IN-19 (Compound 1), a PCSK9 inhibitor, is utilized in researching the treatment of high LDL-cholesterol levels and the prevention of coronary artery disease [1].

    价 格:¥电议型 号:T79239产 地:中国大陆

  • T79000FITC-labeled ODN 2395 sodium;化合物 FITC-labeled ODN 2395 sodiumFITC-labeled ODN 2395 sodium

    FITC-labeled ODN 2395 (sodium), a class C oligodeoxynucleotide and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and localization through confocal laser-scanning microscopy (excitation 495 nm, emission 520 nm) or flow cytometry.

    价 格:¥电议型 号:T79000产 地:中国大陆

  • T78999Biotin-labeled ODN 2395 sodium;化合物 Biotin-labeled ODN 2395 sodiumBiotin-labeled ODN 2395 sodium

    Biotin-labeled ODN 2395 (sodium), a Class C oligodeoxynucleotide and TLR9 agonist, serves to assess cellular uptake and localization of CpG ODN through a biotin detection system coupled with light microscopy.

    价 格:¥电议型 号:T78999产 地:中国大陆

  • T78722ZINC475239213;化合物 ZINC475239213ZINC475239213

    ZINC475239213 acts as an inhibitor targeting the SARS-CoV-2 Nsp14 N7-Methyltransferase with an IC50 value of 20 μM [1].

    价 格:¥电议型 号:T78722产 地:中国大陆

  • T78239Mergetpa;化合物 MergetpaMergetpa

    Mergetpa, a carboxypeptidase inhibitor, impedes the conversion of kinins and B2 receptor antagonists into metabolites devoid of the C-terminal arginine [1].

    价 格:¥电议型 号:T78239产 地:中国大陆

  • T77864SC239;化合物 SC239SC239

    SC239 is a 2-aminophenyl hemiasterlin-based agent-linker suitable for antibody-drug conjugate (ADC) applications. It features a tubulin-targeting warhead, SC209, connected through a cleavable valine-citrulline p-aminobenzyl carbamate linker equipped with dibenzocyclooctyne (DBCO). This drug-linker displays enhanced cytotoxic activity in Igrov1 cells with lower FolRα expression levels.

    价 格:¥电议型 号:T77864产 地:中国大陆

  • T76239Efrilacedase alfa;化合物 Efrilacedase alfaEfrilacedase alfa

    Efrilacedase alfa, an active compound, is utilized for diverse biochemical studies.

    价 格:¥电议型 号:T76239产 地:中国大陆

  • T75239c-Myc inhibitor 10;化合物 c-Myc inhibitor 10c-Myc inhibitor 10

    C-Myc Inhibitor 10 (compound 17), exhibiting enhanced cellular potency, benefits from increased permeability due to the methylation of the morpholine nitrogen [1].

    价 格:¥电议型 号:T75239产 地:中国大陆

  • T74909ODN 2395;化合物 ODN 2395ODN 2395

    ODN 2395, a class C oligodeoxynucleotide and TLR9 agonist, serves as a vaccine adjuvant. Its sequence is 5´-tcgtcgttttcggcgc:gcgccg-3´ [1].

    价 格:¥电议型 号:T74909产 地:中国大陆

  • T74239DOSPA;化合物 DOSPADOSPA

    DOSPA, a cationic lipid, exhibits significant potential when formulated with DNA as a transfection system [1].

    价 格:¥电议型 号:T74239产 地:中国大陆

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