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  • T6976SB 239063;化合物SB239063SB239063;SB239063

    SB 239063 (SB239063) is a potent and selective p38 MAPKα/β inhibitor with IC50 of 44 nM, showing no activity against the γ- and δ-kinase isoforms.

    价 格:¥电议型 号:T6976产 地:中国大陆

  • T69745GDC-2394;化合物 GDC-2394GDC-2394

    GDC-2394, an orally active, selective NLRP3 inhibitor, also targets IL-1β, exhibiting inhibitory concentrations (IC50s) of 0.4 μM (human IL-1β) and 0.1 μM (mouse IL-1β). It effectively hampers NLRP3-induced caspase-1 activity while not affecting NLRC4-dependent inflammasome activation.

    价 格:¥电议型 号:T69745产 地:中国大陆

  • T69239Nylidrin;化合物 NylidrinNylidrin

    Nylidrin is a beta-adrenergic agonist. Nylidrin causes peripheral vasodilation, a positive inotropic effect, and increased gastric volume of gastric juice. It is used in the treatment of peripheral vascular disorders and premature labor.

    价 格:¥电议型 号:T69239产 地:中国大陆

  • T68553MDL-72392;化合物 MDL-72392MDL-72392

    MDL-72392 is a monoamine oxidase inhibitor.

    价 格:¥电议型 号:T68553产 地:中国大陆

  • T68457GSK812397;化合物 GSK812397GSK812397

    GSK812397 is a potent entry inhibitor of X4-tropic strains of HIV-1, as demonstrated in multiple in vitro cellular assays. GSK812397 is a noncompetitive antagonist of the CXCR4 receptor, with GSK812397 producing a concentration-dependent decrease in both an SDF-1-mediated chemotaxis and intracellular calcium release (IC50s were 0.34+/-0.01 nM and 2.41+/-0.50 nM, respectively). GSK812397 is effective against a broad range of X4- and X4R5-utilizing clinical isolates. The potency and efficacy of GS

    价 格:¥电议型 号:T68457产 地:中国大陆

  • T68239NPD4928;化合物 NPD4928NPD4928

    NPD4928 enhanced the sensitivity of various cancer cells to GPX4 inhibitors, suggesting that the combination might have therapeutic potential via the induction of ferroptosis.

    价 格:¥电议型 号:T68239产 地:中国大陆

  • T68177MDL-72394;化合物 MDL-72394MDL-72394

    MDL-72394 is a selective inhibitor of monoamine oxidase (MAO-A).

    价 格:¥电议型 号:T68177产 地:中国大陆

  • T67239Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II);化合物 Tetrakis[(S)-(+)-(1-adamanty

    Tetrakis[(S)-(+)-(1-adamantyl)-(N-phthalimido)acetato]dirhodium(II) is a useful organic compound for research related to life sciences. The catalog number is T67239 and the CAS number is 909389-99-7.

    价 格:¥电议型 号:T67239产 地:中国大陆

  • T66239(Z)-2-(2-((tert-Butoxycarbonyl)amino)thiazol-4-yl)pent-2-enoic acid;化合物 (Z)-2-(2-((tert-Butoxycarbon

    (Z)-2-(2-((tert-Butoxycarbonyl)amino)thiazol-4-yl)pent-2-enoic acid is a useful organic compound for research related to life sciences. The catalog number is T66239 and the CAS number is 86978-24-7.

    价 格:¥电议型 号:T66239产 地:中国大陆

  • T65239L-Leucylglycine;化合物 L-LeucylglycineL-Leucylglycine

    L-Leucylglycine is a useful organic compound for research related to life sciences. The catalog number is T65239 and the CAS number is 686-50-0.

    价 格:¥电议型 号:T65239产 地:中国大陆

  • T64239Belatacept;化合物 BelataceptBelatacept

    Belatacept (BMS 224818) is a selective blocker of T-cell costimulation. Belatacept binds CD 80/86 ligands and thus exhibits an inhibitory effect on CD-28-mediated T-cell costimulation. Belatacept can be used to study organ transplantation immunosuppression.

    价 格:¥电议型 号:T64239产 地:中国大陆

  • T63239FXa-IN-1;化合物 FXa-IN-1FXa-IN-1

    FXa-IN-1 is an FXa inhibitor with an IC50 value of 3 nM and a Ki value of 0.7 nM that exhibits good oral bioavailability and half-life (in vivo) and can be used to study thromboembolic diseases.

    价 格:¥电议型 号:T63239产 地:中国大陆

  • T62399Apoptosis inducer 10;化合物 Apoptosis inducer 10Apoptosis inducer 10

    Apoptosis inducer 10 is a potent apoptosis inducer with anti-proliferative activity. apoptosis inducer 10 induces apoptosis in HeLa cancer cells using a mitochondria-dependent endogenous pathway.

    价 格:¥电议型 号:T62399产 地:中国大陆

  • T62398KH-3;化合物 KH-3KH-3

    KH-3 is a potent inhibitor (IC50: 0.35 μM) of the RNA-binding protein Hu antigen R (HuR) and exhibits anti-proliferative effects. KH-3 interferes with HuR-FOXQ1 Mrna interactions, inhibits breast cancer cell invasion, and delays lung colony formation.

    价 格:¥电议型 号:T62398产 地:中国大陆

  • T62397Epitinib;化合物 EpitinibEpitinib

    Epitinib is an orally active, selective, blood-brain barrier crossing epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI).

    价 格:¥电议型 号:T62397产 地:中国大陆

  • T62396LKB-5492 FA;KB-5492 甲酸盐KB-5492 FA(113594-64-2 Free base);KB-5492 FA(113594-64-2 Free base)

    KB-5492 FA is a selective sigma receptor inhibitor with antiulcerogenic effects.CAS ??128-52-56-8

    价 格:¥电议型 号:T62396L产 地:中国大陆

  • T62396KB-5492 free base;化合物 KB-5492 free baseKB-5492 free base

    KB-5492 free base is an orally available and selective antiulcer agent that inhibits sigma receptors, inhibits [3H]1,3-di(2-tolyl)guanidine (DTG) binding to sigma receptors, and may be useful in the study of gastric lesions and gastric secretion.

    价 格:¥电议型 号:T62396产 地:中国大陆

  • T62395ALK5-IN-32;化合物 ALK5-IN-32ALK5-IN-32

    ALK5-IN-32 is a selective inhibitor of ALK-5 (10 nM

    价 格:¥电议型 号:T62395产 地:中国大陆

  • T62394ALK5-IN-31;化合物 ALK5-IN-31ALK5-IN-31

    ALK5-IN-31 is a selective inhibitor of ALK-5 (IC50≤10 nM) and also inhibits TGF-β-induced SMAD signalling.ALK5-IN-31 has the potential to inhibit tumour growth in vivo.ALK5-IN-31 can be used in the study of proliferative diseases (e.g. cancer, fibrotic diseases, systemic sclerosis).

    价 格:¥电议型 号:T62394产 地:中国大陆

  • T62393ALK5-IN-25;化合物 ALK5-IN-25ALK5-IN-25

    ALK5-IN-25 (compound EX-02) is a potent inhibitor of ALK-5 (IC50<10 nM) and also inhibits ALK-2. ALK5-IN-25 can be used in cancer research.

    价 格:¥电议型 号:T62393产 地:中国大陆

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