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T75418alpha-1,3-Galactosyltransferase (GTB)；化合物 alpha-1,3-Galactosyltransferase (GTB)alpha-1,3-Galactosylt
Alpha-1,3-Galactosyltransferase (GTB) (alpha 1,3GT) is responsible for catalyzing the synthesis of the α-galactose (α-Gal) epitope, known as a xenoantigen. This enzyme facilitates the transfer of galactose from UDP-Gal to either type 1 or type 2 αFuc1→2βGal-R (H)-terminating acceptors [1].
价 格：￥电议型 号：T75418产 地：中国大陆
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T75417alpha-1,3-Galactosyltransferase (a1,3GalT)；化合物 alpha-1,3-Galactosyltransferase (a1,3GalT)alpha-1,3-G
Alpha-1,3-Galactosyltransferase (a1,3GalT) (GGTA1) catalyzes the synthesis of the α-gal epitope by transferring a galactose (Gal) molecule in an α1-3 linkage from a uridyl-diphosphate (UDP) donor to the N-acetyllactosamine (Galβ1,4GlcNAc-R) on glycoproteins. This enzyme is essential for the production of the α-galactose (α-Gal) epitope, a biomolecule prevalent in most mammalian species [1].
价 格：￥电议型 号：T75417产 地：中国大陆
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T75416alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138)；化合物 alpha-1,3-N-Acetylgalactosaminyltransferase
Alpha-1,3-N-Acetylgalactosaminyltransferase (Pm1138) (EC 2.4.1.40(Pm1138)), also known as the ABO system transferase, exhibits glycosyl transferase activity [1].
价 格：￥电议型 号：T75416产 地：中国大陆
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T75415beta-1,3-Galactosyltransferase (CgtB)；化合物 beta-1,3-Galactosyltransferase (CgtB)beta-1,3-Galactosyltr
Beta-1,3-Galactosyltransferase (CgtB) (GM1-synthase), an enzyme critical for the production of sialylated lipooligosaccharide (LOS SIAL), plays a key role in biochemical research. This enzyme facilitates the incorporation of a galactose molecule essential for generating a GM1-like LOS SIAL structure.
价 格：￥电议型 号：T75415产 地：中国大陆
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T75414alpha-1,4-Galactosyltransferase (LgtC)；化合物 alpha-1,4-Galactosyltransferase (LgtC)alpha-1,4-Galactosy
Alpha-1,4-Galactosyltransferase (LgtC) (A4GALT), a glycosphingolipid-specific glycosyltransferase, catalyzes the transfer of a galactose molecule to the alpha-1,4 position on lactosylceramide, resulting in the formation of globotriaosylceramide. This enzyme plays a crucial role in the synthesis of P1 blood group antigens [1] [2].
价 格：￥电议型 号：T75414产 地：中国大陆
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T75413beta-1,4-Galactosyltransferase (LgtB)；化合物 beta-1,4-Galactosyltransferase (LgtB)beta-1,4-Galactosyltr
Beta-1,4-Galactosyltransferase (LgtB) (B4GALT1(LgtB)), a key enzyme in biochemical research, catalyzes the transfer of UDP-galactose to N-acetylglucosamine, resulting in the synthesis of galactose beta-1,4-N-acetylglucosamine [1].
价 格：￥电议型 号：T75413产 地：中国大陆
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T75411beta-1, 3-N-Acetylhexaminyltransferase (LgtA)；化合物 beta-1, 3-N-Acetylhexaminyltransferase (LgtA)beta-
Beta-1, 3-N-Acetylhexaminyltransferase (LgtA), a glycosyltransferase, plays a critical role in biochemical studies by catalyzing the transfer of N-acetylglucosamine from UDP-GlcNAc to substrates including N-acetyllactosamine and lactose [1].
价 格：￥电议型 号：T75411产 地：中国大陆
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T75022JZP-MA-11；化合物 JZP-MA-11JZP-MA-11
JZP-MA-11 is a positron emission tomography (PET) ligand that specifically targets the endocannabinoid α/β-hydrolase domain 6 (ABHD6) enzyme. It exhibits selective inhibition of ABHD6, achieving an IC50 value of 126 nM and is capable of crossing the blood-brain barrier (BBB). The compound, labeled with [18F], demonstrates promising potential for preclinical evaluation in both mice and nonhuman primates (NHP) as a tool for investigating brain ABHD6 activity [1].
价 格：￥电议型 号：T75022产 地：中国大陆
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T74813Sigma-1 receptor antagonist 4；化合物 Sigma-1 receptor antagonist 4Sigma-1 receptor antagonist 4
Sigma-1 receptor antagonist 4 (Compound 32) is a potent σ1R antagonist that significantly enhances morphine´s analgesic effects and reverses morphine-induced analgesic tolerance, potentially preventing morphine tolerance [1].
价 格：￥电议型 号：T74813产 地：中国大陆
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T73693Peginterferon beta-1a；化合物 Peginterferon beta-1aPeginterferon beta-1a
Peginterferon beta-1a (Peginterferon β-1a), the inaugural pegylated interferon beta-1a derivative, promotes apoptosis in cancer cells and exhibits anti-tumor properties in nude mice models. It is utilized in the study of cancer and relapsing multiple sclerosis (RMS) [1].
价 格：￥电议型 号：T73693产 地：中国大陆
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T73377IGUANA-1；化合物 IGUANA-1IGUANA-1
IGUANA-1, a potent ALDH1B1 inhibitor, effectively targets this mitochondrial enzyme involved in promoting colorectal and pancreatic cancer. It exhibits significant inhibition against cancer cells.
价 格：￥电议型 号：T73377产 地：中国大陆
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T7336ICA-121431；化合物ICA-1214312,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl；2,2-Diphenyl-N-[4-(thiazol-2-ylsulf
ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with little or no activity against human Nav1.5 or Nav1.7 channels.
价 格：￥电议型 号：T7336产 地：中国大陆
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T73317JZP-MA-13；化合物 JZP-MA-13JZP-MA-13
JZP-MA-13 is a selective α/β-hydrolase domain 6 (ABHD6) inhibitor, demonstrating impressive specificity with an IC50 value of 392 nM, and exhibits no inhibitory effects on monoacylglycerol lipase (MAGL), ABHD12, fatty acid amide hydrolase (FAAH), or other serine hydrolases. Additionally, JZP-MA-13 serves as a positron emission tomography (PET) ligand for in vivo imaging of ABHD6.
价 格：￥电议型 号：T73317产 地：中国大陆
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T72548IGUANA-1 free base；化合物 IGUANA-1 free baseSTL5-T-0057；STL5-T-0057
IGUANA-1 free base (STL5-T-0057) acts as a selective ALDH1 B1 inhibitor, demonstrating an IC50 value of 30 nM. It efficaciously inhibits the growth of SW480 cells under both adherent and spheroid conditions, yielding IC50 values of 2.46 μM and 0.39 μM, respectively. This compound is utilized in cancer research.
价 格：￥电议型 号：T72548产 地：中国大陆
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T71843HPA-12；化合物 HPA-12HPA-12
HPA-12 is a novel potent inhibitor of cert, binding to the ceramide-binding pocket in the cert start domain
价 格：￥电议型 号：T71843产 地：中国大陆
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T71534LCIA-1 (Free base)；化合物CIA-1CIA-1(Free base）；CIA-1(Free base）
CIA-1 (Free base) is a nuclear receptor COUP-TFII inhibitor with IC50 values ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines. CIA-1 (Free base) inhibits tumor growth in a mouse model of prostate cancer xenografts.
价 格：￥电议型 号：T71534L产 地：中国大陆
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T71534CIA-1 hcl(452087-38-6 Free base)；化合物CIA-1 hcl(452087-38-6 Free base)CIA-1 hcl(452087-38-6 Free base)
CIA-1 inhibits the nuclear receptor COUP-TFII, with IC50s ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines.CIA-1 inhibits the growth of a variety of prostate cancer cell lines in vitro and inhibits COUP-TFII activity to regulate its target genes.CIA-1 in vivo exhibits tumor growth inhibitory effects in a mouse model of prostate cancer xenografts. inhibitory effect on tumor growth in a xenograft mouse model of prostate cancer in vivo.
价 格：￥电议型 号：T71534产 地：中国大陆
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T71426STA-1474；化合物 STA-1474STA-1474
STA-1474 is a water soluble prodrug of ganetespib (formerly STA-9090). STA-1474 will metabolized to Ganetespib, which is a potent HSP90 inhibitor previously shown to kill canine tumor cell lines in vitro and inhibit tumor growth in the setting of murine xenografts. The purpose of the following study was to extend these observations and investigate the safety and efficacy of STA-1474 in dogs with spontaneous tumors.
价 格：￥电议型 号：T71426产 地：中国大陆
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T71202A-1048400；化合物 A-1048400A-1048400
A-1048400 is a potent and selective N-type and T-type calcium channel blocker.
价 格：￥电议型 号：T71202产 地：中国大陆
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T70833A-1293201；化合物 A-1293201A-1293201
A-1293201 is a potent and selective NAMPT inhibitor.
价 格：￥电议型 号：T70833产 地：中国大陆
