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T38842HA-100 hydrochloride;HA-100 hydrochlorideHA-100 hydrochloride
HA-100 hydrochloride is a powerful protein kinase inhibitor, exhibiting IC50 values of 4 μM, 8 μM, 12 μM, and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC), and MLC-kinase, respectively. Additionally, HA-100 hydrochloride is utilized as a ROCK inhibitor.
价 格:¥电议型 号:T38842产 地:中国大陆
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T38817Golgicide A-1;Golgicide A-1GCA-1|||Golgicide A-1;GCA-1|||Golgicide A-1
Golgicide A-1 (GCA-1) is a moderately potent cis-diastereomer variant of Golgicide A (GCA) specifically designed to inhibit mosquito reproduction.
价 格:¥电议型 号:T38817产 地:中国大陆
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T36848Combretastatin A-1;康普瑞汀A-1Combretastatin A1;Combretastatin A1
Combretastatin A-1 is a potent microtubule inhibitor with anti-tumour and anti-vascular activity, acting through microtubule protein depolymerisation-mediated inactivation of AKT to inhibit the Wnt/β-catenin pathway, and can be used to study hepatocellular carcinoma.
价 格:¥电议型 号:T36848产 地:中国大陆
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T35778Ochratoxin A-13C20;Ochratoxin A-13C20Ochratoxin A-13C20;Ochratoxin A-13C20
Ochratoxin A-13C20is intended for use as an internal standard for the quantification of ochratoxin A by GC- or LC-MS. Ochratoxin A is a mycotoxin that has been found inAspergillusandPenicillium.1It increases lipid peroxide levels and the number of apoptotic cells, as well as reduces superoxide dismutase activity in rat kidney when administered at a dose of 120 μg/kg.2Topical application of ochratoxin A (80 μg/mouse) induces DNA damage, cell cycle arrest at the G0/G1phase, and apoptosis in mouse
价 格:¥电议型 号:T35778产 地:中国大陆
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T3528Senicapoc塞尼卡泊塞尼卡泊|||ICA-17043
Senicapoc (ICA-17043) is a potent inhibitor of the Gardos channel and ameliorates RBC dehydration in the SAD mouse. Senicapoc blocked Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ± 2 nM (CLT IC50 = 100 ± 12 nM) and inhibited RBC dehydration with an IC50 of 30 ± 20 nM. Senicapoc is in treatment of Sickle Cell Disease and Sickle Cell Anemia
价 格:¥电议型 号:T3528产 地:中国大陆
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T34767TA-1887;化合物 T34767TA 1887|||TA1887;TA 1887|||TA1887
TA-1887 is a new type of selective inhibitor of sglt2 for the treatment of type 2 diabetes. It has a significant hypoglycemic effect in KK (HF-KK) mice fed a high-fat diet. TA-1887 has good pharmacokinetic characteristics and significantly increases UGE
价 格:¥电议型 号:T34767产 地:中国大陆
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T34686Sonoflora 1;化合物 T34686SF 1|||SF-1|||Sonoflora1|||Sonoflora-1|||SF1;SF 1|||SF-1|||Sonoflora1|||Sonofl
Sonoflora 1, also known as SF1, a PDT photosensitivizer. Chemically, SF1 is an analog of chlorophyll in that its macrocycle backbone is porphyrin-based and the center of the porphyrin ring consists of a metal ion. Preclinical studies showed that SF1 had very high sonodynamic as well as photodynamic activity. The clinically tested results demonstrated positive therapeutic effects for treating patients with advanced refractory breast cancers that had failed to respond to conventional chemotherapy.
价 格:¥电议型 号:T34686产 地:中国大陆
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T34641Silagaba161;化合物 T34641Silagaba-161|||Silagaba 161;Silagaba-161|||Silagaba 161
Silagaba161 is a silicon-containing GABA derivative which treats neuropathic pain without central nervous system related side effects.
价 格:¥电议型 号:T34641产 地:中国大陆
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T34640Silagaba132;化合物 T34640Silagaba 132|||Silagaba-132;Silagaba 132|||Silagaba-132
Silagaba132 is a silicon-containing GABA derivative which treats neuropathic pain without central nervous system related side effects.
价 格:¥电议型 号:T34640产 地:中国大陆
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T33702N-Mercaptoacetyl-L-histidine;化合物 T33702SA 120|||L-Histidine, N-(mercaptoacetyl)-|||SA120|||SA-120;SA
N-Mercaptoacetyl-L-histidine is a peptide.
价 格:¥电议型 号:T33702产 地:中国大陆
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T33698NLA 1;化合物 T33698NLA1|||NLA-1;NLA1|||NLA-1
NLA 1 is a bioreductive compound, a 2-nitroimidazole radiosensitizer embedded in targeted DNA.NLA-1 reversibly binds DNA with an affinity similar to that of 9-aminoacridine and is approximately 1,000 times more potent as a cytotoxin than MISO.
价 格:¥电议型 号:T33698产 地:中国大陆
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T3358ITSA-1化合物ITSA1ITSA1
ITSA-1 is membrane permeable and specifically suppresses TSA inhibition of HDAC (histone deacetylase), but shows no activity towards other HDAC inhibitors.
价 格:¥电议型 号:T3358产 地:中国大陆
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T33276Mefruside;化合物 T33276FDA1902|||FDA-1902|||FDA 1902|||FBA-1500|||FBA1500|||FBA 1500;FDA1902|||FDA-1902
Mefruside is a diuretic indicated for the treatment of edema and hypertension.
价 格:¥电议型 号:T33276产 地:中国大陆
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T32883Lorbamate;化合物 T32883A-19957|||A 19957|||A19957;A-19957|||A 19957|||A19957
Carbamate is a type of carbamate that has been studied as a muscle relaxant and sedative.
价 格:¥电议型 号:T32883产 地:中国大陆
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T32305JNJ-39933673;化合物 T32305JNJ-39933673 hemihydrate|||TA 1887|||TA-1887;JNJ-39933673 hemihydrate|||TA 18
JNJ-39933673 is a bio-active chemical.
价 格:¥电议型 号:T32305产 地:中国大陆
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T31732Evogliptin HCl;化合物 T31732Evogliptin hydrochloride|||DA 1229|||DA1229|||Evogliptin|||DA-1229;Evoglipt
Evogliptin(DA-1229) is a potent and selective DPP4 inhibitor (dipeptidyl peptidase 4 inhibitor) that can improve insulin resistance and delays the onset of diabetes. Evogliptin delays the onset of diabetes in young db/db mice and improves insulin sensitivity in HF mice.
价 格:¥电议型 号:T31732产 地:中国大陆
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T3173DAA-1106;化合物DAA1106DAA1106;DAA1106
DAA-1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine receptor.
价 格:¥电议型 号:T3173产 地:中国大陆
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T31611Eldacimibe;埃得米特WAY-ACA-147|||UNII-4PBL76O2G8|||ANA 147|||ACA 147;WAY-ACA-147|||UNII-4PBL76O2G8|||ANA
Eldacimibe (WAY-ACA-147) is an ACAT2 inhibitor for the treatment of cardiovascular disease and endocrine and metabolic disorders, study of atherosclerosis and hypercholesterolemia.
价 格:¥电议型 号:T31611产 地:中国大陆
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T31424DIBA;化合物 T31424PD022551|||NSC 654077|||DIBA-1|||PD-22551|||DIBA (Antineoplastic);PD022551|||NSC 6540
DIBA is an ER zinc finger inhibitor that inhibits ligand-dependent and non-dependent cell growth in TAM resistant breast cancer in vitro and in vivo.
价 格:¥电议型 号:T31424产 地:中国大陆
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T31277Deca-1,4,9-triene;化合物 T312771-TRANS-4,9-DECATRIENE|||EINECS 233-346-8;1-TRANS-4,9-DECATRIENE|||EINEC
Deca-1,4,9-triene is a biochemical.
价 格:¥电议型 号:T31277产 地:中国大陆