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T0856LDehydroepiandrosteroneDehydroepiandrosterone,Dehydroisoandrosterone,DHEA
Dehydroepiandrosterone (DHEA) is an endogenous steroid hormone that is secreted primarily by the adrenal gland and is the most abundant sex steroid. Although the mechanisms of action of exogenously administered DHEA have not been fully illuminated, they
价 格:¥电议型 号:T0856L产 地:美洲
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T1003610β,17β-dihydroxyestra-1,4-dien-3-one10β,17β-dihydroxyestra-1,4-dien-3-one,DHED,
10β,17β-dihydroxyestra-1,4-dien-3-one is a brain-targeting bioprecursor prodrug of the main human estrogen, 17β-estradiol. It alleviates hot flushes in rat models of thermoregulatory dysfunction of the brain.
价 格:¥电议型 号:T10036产 地:美洲
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T11025DHODH-IN-2DHODH-IN-2
DHODH-IN-2 is an inhibitor of human dihydroorotate dehydrogenase (HsDHODH), which can inhibit measles virus replication, with a pMIC50 value of 8.6.
价 格:¥电议型 号:T11025产 地:美洲
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T11028DHODH-IN-5DHODH-IN-5
DHODH-in -5 is a potent inhibitor of human dihydrogen dehydrogenase (DHODH). For human recombinant DHODH, its pIC50 is 7.8. DHODH-IN-5 inhibits measles virus replication with a pMIC50 of 8.8.
价 格:¥电议型 号:T11028产 地:美洲
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T11032DHPGDHPG,(RS)-3,5-DHPG,
DHPG ((RS)-3,5-DHPG) is also an effective antagonist of mGluR linked to phospholipase D. DHPG ((RS)-3,5-DHPG) is an amino acid that can be used as a selective and potent agonist for Group I mGluR (mGluR 1 and mGluR 5) and has no effect on Group II or Grou
价 格:¥电议型 号:T11032产 地:美洲
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T11043Dihydroergocristine mesylateDihydroergocristine mesylate,DHEC (mesylate),
Dihydroergocryptine mesylate (DHEC mesylate) is an inhibitor of γ-secretase (GSI), which can reduce the production of Alzheimer´s disease amyloid beta peptide, directly at 25.7 nM and 9.8 μM The equilibrium dissociation constant (Kd) binds to γ-secretase
价 格:¥电议型 号:T11043产 地:美洲
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T11044DihydromunduletoneDihydromunduletone,DHM,
Dihydromunduletone (DHM) is a carotenoid derivative and selective strong adhesion G protein-coupled receptor (aGPCR) (GPR56 and GPR114/ADGRG5) antagonists, does not inhibit GPR110 or class A GPCR, IC 50 20.9μM.
价 格:¥电议型 号:T11044产 地:美洲
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T11546hDHODH-IN-1hDHODH-IN-1
hDHODH-IN-1 has anti-inflammatory effect.?hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor.?
价 格:¥电议型 号:T11546产 地:美洲
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T11829LDH-IN-1LDH-IN-1
LDH-IN-1 is a novel pyrazole-based inhibitor of human lactate dehydrogenase (LDH) with IC50s of 32 and 27 nM for LDHA and LDHB, respectively.?
价 格:¥电议型 号:T11829产 地:美洲
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T12189NBDHEXNBDHEX
NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1) .
价 格:¥电议型 号:T12189产 地:美洲
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T1284Megestrol acetateMegestrol acetate,BDH1298,SC10363
Megestrol acetate is a progestogen with actions and uses similar to those of the progestogens in general. Megestrol acetate also has anti-androgenic properties. It is given by mouth in the palliative treatment or as an adjunct to other therapy in endometr
价 格:¥电议型 号:T1284产 地:美洲
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T13379(Z)-Leukadherin-1(Z)-Leukadherin-1,ADH-503 free base,
(Z)-Leukadherin-1 is an orally active and allosteric agonist of CD11b.
价 格:¥电议型 号:T13379产 地:美洲
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T13462(+)-DHMEQ(+)-DHMEQ,(1R,2R,6R)-Dehydroxymethylepoxyquinomicin,(1R,2R,6R)-DHMEQ
(+)-DHMEQ is an antioxidant transcription factor Nrf2 activator. (+)-DHMEQ is the enantiomer of (-)-DHMEQ.
价 格:¥电议型 号:T13462产 地:美洲
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T13604CDDO-dhTFEACDDO-dhTFEA,RTA dh404,
CDDO-dhTFEA (RTA dh404), a synthetic oleanane triterpenoid compound, potently activates Nrf2 and inhibits NF-κB.
价 格:¥电议型 号:T13604产 地:美洲
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T1423Hydroxytoluic acidHydroxytoluic acid,3-Methylsalicylic acid,o-Cresotic acid
Hydroxytoluic Acid is a long-acting salicylate derivative with antilipidemic properties. Hydroxytoluic acid has been shown to lower plasma free fatty acid and cholesterol levels.
价 格:¥电议型 号:T1423产 地:美洲
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T15362FX-11FX-11,LDHA Inhibitor FX11,
FX-11 is a potent inhibitor of lactate dehydrogenase A (LDHA) (IC50: 23.3 μM for HeLa cell and Ki: 8 μM).
价 格:¥电议型 号:T15362产 地:美洲
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T15550IDH-305IDH-305
IDH-305 shows greater than 200 fold selectivity for mutant IDH1 isoforms vs. WT (IC50= 27 nM (IDH1R132H), 28 nM (IDH1R132C), 6.14 ?M (IDH1WT)). IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor.
价 格:¥电议型 号:T15550产 地:美洲
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T15551IDH889IDH889
IDH889 displays effective cellular inhibition of R-2-hydroxyglutarate (2-HG) production (IC50: 0.014 μM). IDH889 has effective selectivity for IDH1 R132* mutations (C50s of 0.02 μM, 0.072 μM, and 1.38 μM for IDH1R132H, IDH1R132C, and IDH1wt, respectively)
价 格:¥电议型 号:T15551产 地:美洲
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T1608Exherin trifluoroacetateExherin trifluoroacetate,ADH-1 trifluoroacetate,
Exherin (ADH-1) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities. ADH-1 selectively and competitively binds to and blocks N-cadherin, which may result in disruption of tumor vasculature, inhibit
价 格:¥电议型 号:T1608产 地:美洲
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T16161Mutant IDH1 inhibitorMutant IDH1 inhibitor
Mutant IDH1 inhibitor is an effective inhibitor of mutant IDH1 R132H (IC50: < 72 nM).
价 格:¥电议型 号:T16161产 地:美洲