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  • T82569DHX9-IN-1；化合物 DHX9-IN-1DHX9-IN-1

    DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].

    价 格：￥电议型 号：T82569产 地：中国大陆

  • T82568DHX9-IN-2；DHX9 抑制剂2DHX9-IN-2

    DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.

    价 格：￥电议型 号：T82568产 地：中国大陆

  • T82493EGFR/HER2/DHFR-IN-2；化合物 EGFR/HER2/DHFR-IN-2EGFR/HER2/DHFR-IN-2

    EGFR/HER2/DHFR-IN-2 (Compound 4b) serves as an inhibitor for EGFR, HER2, and DHFR, with IC50 values of 0.248, 0.156, and 0.138 μM, respectively. It exhibits anticancer activity, displaying IC50 values of 9.14, 7.33, 14.18, 24.87, 20.07, and 6.16 μM in Hep G2, HeLa, HEp-2, HCT 116, PC-3, and MCF7 cancer cell lines, respectively. Additionally, EGFR/HER2/DHFR-IN-2 has been shown to reduce the growth of breast cancer tumors [1].

    价 格：￥电议型 号：T82493产 地：中国大陆

  • T82492EGFR/HER2/DHFR-IN-3；化合物 EGFR/HER2/DHFR-IN-3EGFR/HER2/DHFR-IN-3

    EGFR/HER2/DHFR-IN-3 (compound 4c) serves as an efficacious dual inhibitor specifically targeting EGFR/HER2, exhibiting IC50 values of 0.138 μM for EGFR and 0.092 μM for HER2, respectively. Moreover, it demonstrates inhibition of DHFR with an IC50 of 0.193 μM. Notably, this compound induces cell cycle arrest in the S phase and triggers apoptosis in MCF7 breast cancer cells [1].

    价 格：￥电议型 号：T82492产 地：中国大陆

  • T82223hDHODH-IN-13；化合物 hDHODH-IN-13hDHODH-IN-13

    hDHODH-IN-13 (compound w2), an inhibitor of human dihydroorotate dehydrogenase (hDHODH), exhibits an IC50 of 173.4 nM and has potential research applications in studying inflammatory bowel disease (IBD) [1].

    价 格：￥电议型 号：T82223产 地：中国大陆

  • T82207Hexanorcucurbitacin D；化合物 Hexanorcucurbitacin DHexanorcucurbitacin D

    Hexanorcucurbitacin D, a cucurbitacin, is extractable from the roots of Trichosanthes cucumeroides and is utilized in cardiovascular disease (CVD) research [1].

    价 格：￥电议型 号：T82207产 地：中国大陆

  • T82184Hosenkoside D；化合物 Hosenkoside DHosenkoside D

    Hosenkoside D is a baccharane-type glycoside [1].

    价 格：￥电议型 号：T82184产 地：中国大陆

  • T82151Hyaluronan-binding peptide, biotin labeled；化合物 Hyaluronan-binding peptide, biotin labeledHyaluronan-

    Biotin-labeled Hyaluronan-binding Peptide is a biologically active peptide conjugated with biotin via a C-terminal GGGSK linker. It interacts with the non-sulfated glycosaminoglycan hyaluronan (HA), prominent in the extracellular matrix and on cellular surfaces, involved in processes such as fertilization, embryonic development, wound healing, angiogenesis, leukocyte migration, and cancer metastasis. The peptide impedes HA´s interaction with CD44 receptors and curtails T cell proliferation

    价 格：￥电议型 号：T82151产 地：中国大陆

  • T81593Osteoblast-Adhesive Peptide；化合物 Osteoblast-Adhesive PeptideOsteoblast-Adhesive Peptide

    Osteoblast-Adhesive Peptide, a polypeptide designed for biomaterials´ chemical modification, enhances osteoblast adhesion, showing promise for use in dentistry and orthopedics [1] [2].

    价 格：￥电议型 号：T81593产 地：中国大陆

  • T81381PROTAC eDHFR Degrader-1；化合物 PROTAC eDHFR Degrader-1PROTAC eDHFR Degrader-1

    PROTAC eDHFR Degrader-1 is a potent degrader targeting eDHFR-YFP and various proteins of interest (POIs), such as YFP and Luciferase [1].

    价 格：￥电议型 号：T81381产 地：中国大陆

  • T81185SDH-IN-10；化合物 SDH-IN-10SDH-IN-10

    SDH-IN-10 is a potent inhibitor of succinate dehydrogenase (SDHI) that exhibits antifungal activity [1].

    价 格：￥电议型 号：T81185产 地：中国大陆

  • T79765SDH-IN-9；化合物 SDH-IN-9SDH-IN-9

    SDH-IN-9 (compound Ip) serves as a potent Succinate Dehydrogenase inhibitor and exhibits fungicidal properties, effectively targeting Fusarium graminearum Schw at an EC50 value of 0.93 μg/mL [1].

    价 格：￥电议型 号：T79765产 地：中国大陆

  • T79745IDH2R140Q-IN-2；IDH2R140Q 抑制剂1IDH2R140Q-IN-2

    IDH2R140Q-IN-2 is an orally active and potent IDH2R140Q inhibitor with an IC50 of 29 nM.IDH2R140Q-IN-2 possesses potential antitumour activity, reducing D2HG production in TF-1 cell lines carrying the IDH2R140Q mutation (IC50 of 10 nM) and inhibiting tumour tissue D2HG levels.IDH2R140Q-IN-2 is suitable for the study of acute myeloid leukaemia (AML).

    价 格：￥电议型 号：T79745产 地：中国大陆

  • T79735DHFR-IN-9；化合物 DHFR-IN-9DHFR-IN-9

    DHFR-IN-9 (compound 8A), a dihydrofolate reductase (DHFR) inhibitor, impedes purine and thymidylate biosynthesis, pivotal in cell proliferation and growth. It demonstrates potency against methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 with an IC50 of 0.25 μg/mL and exhibits anti-infective properties in mouse systemic and thigh infection models at doses of 2.5 mg/kg and 5 mg/kg administered intraperitoneally (ip). Furthermore, DHFR-IN-9 shows greater anticancer efficacy in a mouse

    价 格：￥电议型 号：T79735产 地：中国大陆

  • T79734DHFR-IN-8；化合物 DHFR-IN-8DHFR-IN-8

    DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth. This compound effectively suppresses methicillin-resistant Staphylococcus aureus (MRSA) ATCC 43300 with an IC50 of 15.6 ng/mL in mouse models of systemic and thigh infections [1].

    价 格：￥电议型 号：T79734产 地：中国大陆

  • T79544SDH-IN-6；化合物 SDH-IN-6SDH-IN-6

    SDH-IN-6 (compound 6i), a potent inhibitor of succinate dehydrogenase (SDH), exhibits antifungal efficacy against Valsa mali, demonstrated by an EC50 value of 1.77 mg/L [1].

    价 格：￥电议型 号：T79544产 地：中国大陆

  • T79238SDH-IN-3；化合物 SDH-IN-3SDH-IN-3

    SDH-IN-3 is a succinate dehydrogenase (SDH) inhibitor, demonstrating potent antifungal activity with an inhibition concentration (IC50) of 7.2 μg/mL and an effective concentration (EC50) of 1.9 μg/mL against Nigrospora oryzae. This compound is valuable for anti-infection research [1].

    价 格：￥电议型 号：T79238产 地：中国大陆

  • T78932hDHODH-IN-12；化合物 hDHODH-IN-12hDHODH-IN-12

    hDHODH-IN-12 is a potent inhibitor of dihydroorotate dehydrogenase (DHODH), exhibiting an inhibitory concentration (IC50) of 0.421 μM. As the rate-limiting enzyme in the de novo synthesis of pyrimidines, critical for DNA/RNA synthesis, DHODH is localized within the inner membrane of human mitochondria. hDHODH-IN-12 is applicable in lung cancer research [1].

    价 格：￥电议型 号：T78932产 地：中国大陆

  • T78931SDH-IN-5；化合物 SDH-IN-5SDH-IN-5

    SDH-IN-5 (compound 7d), a potent inhibitor of succinate dehydrogenase (SDH) with an IC50 of 3.293 μM, additionally demonstrates antifungal efficacy, exhibiting an EC50 of 0.046 μg/mL against R. solani. Moreover, SDH-IN-5 significantly hampers R. solani growth in rice leaves, showcasing outstanding protective and curative effects [1].

    价 格：￥电议型 号：T78931产 地：中国大陆

  • T78891SDH-IN-8；化合物 SDH-IN-8SDH-IN-8

    SDH-IN-8 (compound G40) is a potent inhibitor of succinate dehydrogenase (SDH), demonstrating an IC50 value of 27 nM against porcine SDH and exhibits fungicidal properties [1].

    价 格：￥电议型 号：T78891产 地：中国大陆

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