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T78890SDH-IN-7；化合物 SDH-IN-7SDH-IN-7
SDH-IN-7 (compound G28) is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 26 nM against porcine SDH and possesses fungicidal properties [1].
价 格：￥电议型 号：T78890产 地：中国大陆
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T78758IHMT-IDH1-053；化合物 IHMT-IDH1-053IHMT-IDH1-053
IHMT-IDH1-053 (compound 16) is an irreversible inhibitor exhibiting high selectivity for the IDH1 R132H mutant, achieving an IC50 of 4.7 nM. It preferentially targets IDH1 mutants over wild-type IDH1 and IDH2, both wild-type and mutants. In 293T cells transfected with the IDH1 R132H mutant, IHMT-IDH1-053 reduces 2-hydroxyglutarate (2-HG) production with an IC50 value of 28 nM. The compound engages with the R132H protein at an allosteric site near the NAPDH binding region, forming a covalent link
价 格：￥电议型 号：T78758产 地：中国大陆
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T78727SDH-IN-4；化合物 SDH-IN-4SDH-IN-4
SDH-IN-4 (compound B6) is a selective succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.28 ?g/mL, exhibiting potent and wide-ranging antifungal effects, including an EC50 of 0.23 ?g/mL against R. solani [1].
价 格：￥电议型 号：T78727产 地：中国大陆
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T78565Dihydro-5-azacytidine acetate；化合物 Dihydro-5-azacytidine acetateDHAC acetate|||NSC 264880 acetate；DHA
Dihydro-5-azacytidine acetate (DHAC), a nucleoside analog, becomes integrated into DNA, thereby inhibiting DNA methylation, and exhibits antitumor activity [1] [2].
价 格：￥电议型 号：T78565产 地：中国大陆
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T78360Glyceraldehyde phosphate dehydrogenase；化合物 Glyceraldehyde phosphate dehydrogenaseGAPDH|||G3PDH|||GAD
Glyceraldehyde phosphate dehydrogenase, targeted by anti-thymocyte and anti-apoptotic agents, catalyzes the oxidation of reduced nicotinamide adenine dinucleotide (NADH) by perhydroxyl radicals [1] [2].
价 格：￥电议型 号：T78360产 地：中国大陆
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T7776ADH-503；化合物ADH-503GB1275；GB1275
ADH-503 (GB1275) is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.
价 格：￥电议型 号：T7776产 地：中国大陆
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T76467Acetyl-Adhesin (1025-1044) amide；化合物 Acetyl-Adhesin (1025-1044) amideAcetyl-Adhesin (1025-1044) amid
Acetyl-Adhesin (1025-1044) amide, a 20-peptide fragment derived from the cell surface adhesin of Streptococcus pyogenes, functions as an antimicrobial peptide. It specifically prevents Streptococcus pyogenes recolonization by inhibiting the adhesin´s binding to salivary receptors [1].
价 格：￥电议型 号：T76467产 地：中国大陆
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T76207Glucose dehydrogenase (GDH)；化合物 Glucose dehydrogenase (GDH)Glucose dehydrogenase (GDH)
Glucose dehydrogenase (GDH) is an oxidoreductase enzyme that facilitates the oxidation of β-D-glucose into β-D-glucono-1,5-lactone, while concurrently reducing cofactor NADP+ to NADPH, and to a lesser degree, NAD+ to NADH. It can utilize both NAD+ and NADP+ as cofactors and serves in the regeneration of NADH and NADPH [1] [2].
价 格：￥电议型 号：T76207产 地：中国大陆
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T75692Hypoglaunine D；化合物 Hypoglaunine DHypoglaunine D
Hypoglaunine D, an analogue of Triptonine B, serves as an anti-HIV compound by inhibiting HIV replication in H9 lymphocytes, demonstrating an efficacy with an EC50 value of 22 μg/ml [1].
价 格：￥电议型 号：T75692产 地：中国大陆
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T7563NBI-98782；(+)-α-二氢丁苯那嗪(+)-α-Dihydrotetrabenazine|||(+)-α-DHTBZ|||(+)-DTBZ；(+)-α-二氢丁苯那嗪|||(+)-α-Dihyd
NBI-98782 ((+)-α-DHTBZ) is an inhibtior of vesicular monoamine transporter (VMAT2) (Ki: 0.97 nM)
价 格：￥电议型 号：T7563产 地：中国大陆
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T7488BD1063 dhydrochloride；化合物BD1063BD1063；BD1063
BD1063 dhydrochloride is a potent and selective sigma 1(σ1) receptor antagonist(Ki = 9 nM).
价 格：￥电议型 号：T7488产 地：中国大陆
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T74756SDH-IN-2；SDH抑制剂2SDH-IN-2
SDH-IN-2 is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 0.55 μg/mL.SDH-IN-2 possesses antifungal activity, with average EC50 values of 3.82-9.81 μg/mL for inhibition of plant pathogenic fungi.
价 格：￥电议型 号：T74756产 地：中国大陆
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T74443ADH-6 TFA；化合物 ADH-6 TFAADH-6 TFA
ADH-6 TFA, a tripyridylamide compound, effectively disrupts the self-assembly of the aggregation-nucleating subdomain of mutant p53 DBD, thereby targeting and disassociating mutant p53 aggregates in human cancer cells. This action restores the transcriptional activity of p53, resulting in cell cycle arrest and apoptosis. Consequently, ADH-6 TFA holds potential for cancer research [1].
价 格：￥电议型 号：T74443产 地：中国大陆
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T74235DHAPC；化合物 DHAPC1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine；1,2-Didocosahexaenoyl-sn-glycero-3-
DHAPC (1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine) can be used as a fluorine-18 radiolabeling agent for PET imaging of prostate cancer.
价 格：￥电议型 号：T74235产 地：中国大陆
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T74193(R)-IDHP；化合物 (R)-IDHP(R)-IDHP
(R)-IDHP, an isomer of IDHP and a metabolite of salvia, exhibits vasorelaxant properties by inhibiting calcium (Ca 2+) release and inward flow through both voltage-dependent and receptor-operated calcium channels in vascular smooth muscle cells. It is utilized in cardiovascular disease research [1].
价 格：￥电议型 号：T74193产 地：中国大陆
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T73533ADH-6；化合物 ADH-6ADH-6
ADH-6, a tripyridylamide compound, impedes the self-assembly of the aggregation-nucleating subdomain of mutant p53 DNA-binding domain (DBD). By targeting and dissociating mutant p53 aggregates in human cancer cells, ADH-6 reinstates p53´s transcriptional activity, culminating in cell cycle arrest and apoptosis, thereby holding potential for cancer research.
价 格：￥电议型 号：T73533产 地：中国大陆
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T7338LDHBP；紫外线吸收剂Benzoresorcinol；紫外线吸收剂|||Benzoresorcinol
DHBP (Benzoresorcinol) is an WalKR TCS activator. It works via targeting walk and selectively promoting the lysostaphin-induced lysis activity of the Newman wild-type strain.
价 格：￥电议型 号：T7338L产 地：中国大陆
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T73328DHFR-IN-5；化合物 DHFR-IN-5DHFR-IN-5
DHFR-IN-5, an orally active and potent inhibitor of dihydrofolate reductase (DHFR), exhibits a K_i value of 0.54 nM against the quadruple mutant Plasmodium falciparum DHFR, demonstrating anti-malarial activity.
价 格：￥电议型 号：T73328产 地：中国大陆
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T73222LDHA-IN-5；化合物 LDHA-IN-5LDHA-IN-5
LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primary hyperoxaluria.
价 格：￥电议型 号：T73222产 地：中国大陆
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T73143PHGDH-IN-3；化合物PHGDH-IN-3PHGDH-IN-3
PHGDH-IN-3 is an orally active phosphoglycerate dehydrogenase (PHGDH) inhibitor with an IC50 of 2.8 μM against PHGDH. PHGDH-IN-3 can be used in studies about cancer.
价 格：￥电议型 号：T73143产 地：中国大陆
