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T6605NH125;化合物NH125NH125
NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor.
价 格:¥电议型 号:T6605产 地:中国大陆
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T6506FPH1;化合物FPH1BRD-6125;BRD-6125
FPH1 (BRD-6125) (BRD-6125) can promote the expansion of iPS-derived hepatocytes.
价 格:¥电议型 号:T6506产 地:中国大陆
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T64662MDH1/2 inhibitor compound 16c;化合物 MDH1/2 inhibitor compound 16cMDH1/2 inhibitor compound 16c
MDH1/2 inhibitor compound 16c is a useful organic compound for research related to life sciences and the catalog number is T64662.
价 格:¥电议型 号:T64662产 地:中国大陆
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T64347ALDH1A3-IN-3;化合物ALDH1A3-IN-3ALDH1A3-IN-3
ALDH1A3-IN-3 (compound 16), a powerful ALDH1A3 inhibitor with an IC50 of 0.26 μM, serves as an effective ALDH3A1 substrate. It is utilized in prostate cancer research.
价 格:¥电议型 号:T64347产 地:中国大陆
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T64228ALDH1A1-IN-3;化合物 ALDH1A1-IN-3ALDH1A1-IN-3
ALDH1A1-IN-3 is a good and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1) (IC50: μM).ALDH1A1-IN-3 is effective in improving glucose consumption in HepG2 cells.ALDH1A1-IN-3 can be used for studies to improve glucose metabolism.
价 格:¥电议型 号:T64228产 地:中国大陆
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T63403WT IDH1 Inhibitor 2;化合物 WT IDH1 Inhibitor 2WT IDH1 Inhibitor 2
WT IDH1 Inhibitor 2 is a wild-type isocitrate dehydrogenase 1 (WT IDH1) inhibitor (IC50: 120 nM) and is a mutant R132H IDH1 inhibitor, an isoform of GSK321 with wild-type cross-reactivity.
价 格:¥电议型 号:T63403产 地:中国大陆
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T63402(S,R)-WT IDH1 Inhibitor 2;化合物 (S,R)-WT IDH1 Inhibitor 2(S,R)-WT IDH1 Inhibitor 2
(S,R)-WT IDH1 Inhibitor 2 is a selective and potent mutant IDH1 inhibitor that inhibits R132G (IC50: 2.9 nM), R132C (IC50: 3.8 nM), R132H (IC50: 4.6 nM) and WT IDH1 (IC50: 46 nM) with 100-fold higher selectivity than IDH2. 100-fold higher selectivity than IDH2. (S,R)-WT IDH1 Inhibitor 2 is investigated in acute myeloid leukemia (AML) and other cancers for its ability to induce intracellular 2-HG reduction, failure of myeloid differentiation block, and induction of granulocyte differentiation at
价 格:¥电议型 号:T63402产 地:中国大陆
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T63341ALDH1A1-IN-2;ALDH1A1抑制剂2ALDH1A1-IN-2
ALDH1A1-IN-2 is a potent aldehyde dehydrogenase 1a1 (aldh1a1) inhibitor with anticancer activity.ALDH1A1-IN-2 may be used in the study of breast cancer, inflammation or obesity.
价 格:¥电议型 号:T63341产 地:中国大陆
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T62725IDH1 Inhibitor 5;化合物 IDH1 Inhibitor 5IDH1 Inhibitor 5
IDH1 Inhibitor 5 (compound 2) is an inhibitor of IDH1 (isocitrate dehydrogenase 1), which inhibits MOG cells (IC50: 64.4 nM) and wild-type IDH1 glioma cells expressing exogenous mutant IDH1 R132H protein (IC50: 34.9 nM).
价 格:¥电议型 号:T62725产 地:中国大陆
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T62335MDH1-IN-2;MDH抑制剂2MDH1-IN-2
MDH1-IN-2 is a potent MDH1 inhibitor with potential anticancer activity for the study of diseases related to the immune system.
价 格:¥电议型 号:T62335产 地:中国大陆
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T61270MDH1-IN-1;MDH抑制剂1MDH1-IN-1
MDH1-IN-1 is a potent MDH1 inhibitor with potential anticancer activity for the study of diseases related to the immune system.
价 格:¥电议型 号:T61270产 地:中国大陆
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T60550ALDH1A3-IN-1;化合物 ALDH1A3-IN-1ALDH1A3-IN-1
ALDH1A3-IN-1 (Compound 14) is a potent inhibitor of ALDH1A3 which can be used in prostate cancer research (IC50 = 0.63 μM; Ki = 0.46 μM) [1].
价 格:¥电议型 号:T60550产 地:中国大陆
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T60240ALDH1A3-IN-2;化合物ALDH1A3-IN-2ALDH1A3-IN-2
ALDH1A3-IN-2 is a potent ALDH1A3 inhibitor with an IC50 of 0.30 μM.ALDH1A3-IN-2 has potential for cancer disease research.
价 格:¥电议型 号:T60240产 地:中国大陆
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T60034TH1085;化合物TH1085TH1085
TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).
价 格:¥电议型 号:T60034产 地:中国大陆
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T5209INH14;化合物INH14INH14
INH14 is a novel inhibitor of the IKKα/β-dependent TLR inflammatory response (IC50s: 8.97/3.59 μM for IKKα/IKKβ).
价 格:¥电议型 号:T5209产 地:中国大陆
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T4138UCPH-101;化合物UCPH101UCPH 101;UCPH 101
UCPH-101 is an inhibitor of excitatory amino acid transporter subtype 1 (EAAT1) with an IC50 of 0.66 μM.
价 格:¥电议型 号:T4138产 地:中国大陆
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T41019Histone H1-derived Peptide;Histone H1-derived PeptideHistone H1-derived Peptide;Histone H1-derived P
Histone H1-derived peptide is a phosphopeptide with peptide substrates that consist of a sequence aligned with the optimal recognition motif for cyclin-dependent kinases (CDKs).
价 格:¥电议型 号:T41019产 地:中国大陆
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T39716Mutant IDH1-IN-6Mutant IDH1-IN-6Mutant IDH1-IN-6
Mutant IDH1-IN-6 is an orally active compound that effectively inhibits mutant isocitrate dehydrogenase (IDH) enzymes. It demonstrates potency and selectivity, with IC50 values of 6.27, 3.71, 36.9, and 11.5 nM for IDH1 R132H, IDH1 R132C, IDH2 R140Q, and IDH2 R172K mutants, respectively. Notably, Mutant IDH1-IN-6 exhibits lower activity in inhibiting wild-type IDH enzymes.
价 格:¥电议型 号:T39716产 地:中国大陆
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T39675ALDH1A2-IN-1ALDH1A2-IN-1ALDH1A2-IN-1
ALDH1A2-IN-1 is a reversible inhibitor of the active site of ALDH1A2, showing a significant affinity for the enzyme with an IC50 value of 0.91 μM and a Kd value of 0.26 μM. This compound interacts hydrophobically with the enzyme, contributing to its inhibitory properties.
价 格:¥电议型 号:T39675产 地:中国大陆
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T39554TH1834TH1834TH1834
TH1834 is a selective inhibitor of the Tip60 (KAT5) histone acetyltransferase (HAT). It effectively induces apoptosis and promotes DNA damage in breast cancer cells. Notably, TH1834 does not influence the activity of the MOF histone acetyltransferase, which is structurally related. Overall, TH1834 exhibits potent anticancer activity.
价 格:¥电议型 号:T39554产 地:中国大陆