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T11826LCH-7749944；化合物LCH-7749944GNF-PF-2356；GNF-PF-2356
LCH-7749944 (GNF-PF-2356) effectively suppresses the proliferation of human gastric cancer cells through downregulation of PAK4/c-Src/EGFR/cyclin D1 pathway and induces apoptosis. LCH-7749944 is a potent PAK4 inhibitor with an IC50 of 14.93 μM.
价 格：￥电议型 号：T11826产 地：中国大陆
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T11823LB-60-OF61；化合物 LB-60-OF61LB-60-OF61
LB-60-OF61 is a NAMPT inhibitor, a NAMPT inhibitor that displays antiproliferative activity against MYC oncogene-dependent cancer cell lines.
价 格：￥电议型 号：T11823产 地：中国大陆
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T1181LGefitinib hydrochloride；化合物 T1181LGefitinib hydrochloride
Gefitinib hydrochloride (ZD1839 hydrochloride) is a potent and orally active EGFR tyrosine kinase inhibitor (EGFR-TKI) (IC 50 = 33 nM) that selectively inhibits EGF-stimulated tumor cell growth (IC 50 = 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib hydrochloride also induces autophagy, which has antitumour activity [1] [2].
价 格：￥电议型 号：T1181L产 地：中国大陆
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T11819Lascufloxacin；拉库沙星KRP-AM1977X；拉库沙星|||KRP-AM1977X
Lascufloxacin, a potent and orally active fluoroquinolone antibacterial agent, holds potential for the treatment of various infectious diseases, including lower respiratory tract infections. It effectively inhibits infections caused by a wide range of pathogens, encompassing those resistant to quinolones.
价 格：￥电议型 号：T11819产 地：中国大陆
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T11813Laflunimus；化合物 T11813HR325；HR325
Laflunimus suppresses immunoglobulin (Ig) secretion, with IC50 values of 2.5 and 2 μM for IgM and IgG, respectively. Laflunimus also is a prostaglandin endoperoxide H synthase (PGHS) -1 and -2 inhibitor. Laflunimus is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus is an orally active inhibitor of dihydroorotate dehydrogenase (DHODH).
价 格：￥电议型 号：T11813产 地：中国大陆
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T11812LL-Eflornithine monohydrochloride化合物 T11812LL-α-difluoromethylornithine monohydrochloride|||L-RMI7178
L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 μM, and a Kinact of 0.15±0.03 min-1. L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine.
价 格：￥电议型 号：T11812L产 地：中国大陆
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T11812L-Eflornithine；L-依氟鸟氨酸L-α-difluoromethylornithine|||L-RMI71782|||L-DFMO；L-依氟鸟氨酸|||L-α-difluoromethyl
L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 μM, and a Kinact of 0.15±0.03 min-1. L-Eflornithine is an enantiomer of Eflornithine.
价 格：￥电议型 号：T11812产 地：中国大陆
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T1181Gefitinib；吉非替尼ZD1839；ZD1839|||吉非替尼
Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell lung cancers. Gefitinib administration RESULTS in the development of the EGFR C797S resistance mutation.
价 格：￥电议型 号：T1181产 地：中国大陆
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T11803L-Cysteinesulfinic acid；L-半胱氨酸亚磺酸L-Cysteinesulfinic acid
L-Cysteinesulfinic acid is a potent agonist at several rat metabotropic glutamate receptors (mGluRs, pEC50s of 3.92±0.03, 4.6±0.2, 3.9±0.2, 2.7±0.2, 4.0±0.2, and 3.94±0.08 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively).
价 格：￥电议型 号：T11803产 地：中国大陆
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T11792KW-8232 free base；化合物 T11792KW-8232 free base
KW-8232 free base can reduces the biosynthesis of PGE2, is an anti-osteoporotic agent.
价 格：￥电议型 号：T11792产 地：中国大陆
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T1177Sulfaquinoxaline；磺胺喹噁啉Avicocid|||Sulphaquinoxaline|||Sulfabenzpyrazine；磺胺喹恶啉|||Avicocid|||磺胺喹噁啉|||Su
Sulfaquinoxaline (Sulfabenzpyrazine) is an antiprotozoal agent.
价 格：￥电议型 号：T1177产 地：中国大陆
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T11760KIN101；3-(4-溴苯基)-4-氧代-7-[(甲磺酰基)氧基]-4H-色烯3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene；
KIN101 (3-(4-Bromophenyl)-7-[(methylsulfonyl)oxy]-4-oxo-4H-chromene), an isoflavone agonist of IRF-3 dependent signaling, induces IRF-3 nuclear translocation. KIN101 has antiviral activity against RNA viruses, HCV, and RSV.
价 格：￥电议型 号：T11760产 地：中国大陆
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T11759Kif15-IN-2；化合物 T11759Kif15-IN-2
Kif15-IN-2 is used for the research of cellular proliferative diseases. Kif15-IN-2 is an inhibitor of the mitotic kinesin Kif15.
价 格：￥电议型 号：T11759产 地：中国大陆
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T11755KF 13218；化合物 T11755KF 13218
KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.
价 格：￥电议型 号：T11755产 地：中国大陆
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T1175217-BFC；7-苄氧基-4-三氟甲基香豆素7-Benzyloxy-4-(trifluoromethyl)coumarin|||Y040-0031；7-Benzyloxy-4-(trifluoromet
7-BFC (7-Benzyloxy-4-(trifluoromethyl)coumarin) is a coumarin-like fluorescent substrate that serves as a biomarker for cytochrome P 450 and can be used to study CYP isoforms and cytochrome P 450 metabolism.
价 格：￥电议型 号：T117521产 地：中国大陆
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T11750LKDOAM-25 trihydrochloride (2230731-99-2 free base)；化合物 T11750LKDOAM-25 trihydrochloride；KDOAM-25 tri
KDOAM-25 trihydrochloride increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells. KDOAM-25 trihydrochloride is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively.
价 格：￥电议型 号：T11750L产 地：中国大陆
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T1174Topotecan hydrochloride；盐酸拓扑替康SKF 104864A|||SKFS 104864A|||NSC609699|||Nogitecan HCl|||NSC 609669|||
Topotecan hydrochloride (NSC609699) is an antineoplastic agent used to treat ovarian cancer.
价 格：￥电议型 号：T1174产 地：中国大陆
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T11732JTV-519 hemifumarate；化合物 T11732K201 hemifumarate；K201 hemifumarate
JTV-519 hemifumarate,Antiarrhythmic and cardioprotective properties. is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle.
价 格：￥电议型 号：T11732产 地：中国大陆
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T11731LJTV-519 Formate；化合物JTV-519 FormateJTV-519 Formate (145903-06-6 Free base)；JTV-519 Formate (145903-06
JTV-519 Formate is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA). JTV-519 Formate is also a partial agonist of ryanodine receptors in striated muscle. JTV-519 Formate exhibits antiarrhythmic and cardioprotective properties.
价 格：￥电议型 号：T11731L产 地：中国大陆
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T11731JTV-519 free base；化合物 T11731K201 free base；K201 free base
JTV-519 free base (K201 free base), recognized for its antiarrhythmic and cardioprotective properties, functions as a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and serves as a partial agonist of ryanodine receptors in striated muscle.
价 格：￥电议型 号：T11731产 地：中国大陆
