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T11487Fiboflapon;化合物FiboflaponGSK2190915|||AM-803;GSK2190915|||AM-803
Fiboflapon (GSK2190915) is an orally available and effective 5-lipoxygenase-activating protein (FLAP) inhibitor that binds FLAP with a titer of 2.9 nM and inhibition of LTB4 in human blood with an IC50 of 76 nM.
价 格:¥电议型 号:T11487产 地:中国大陆
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T11486GSK2807 Trifluoroacetate;化合物GSK2807 TrifluoroacetateGSK2807 Trifluoroacetate
GSK2807 Trifluoroacetate is a selective and SAM-competitive inhibitor of SMYD3 (Ki: 14 nM; IC50: 130 nM).
价 格:¥电议型 号:T11486产 地:中国大陆
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T11483GSK256066 Trifluoroacetate化合物 T11483GSK 256066 Trifluoroacetate|||GSK256066 (2,2,2-trifluoroacetic a
GSK 256066 Trifluoroacetate is a selective and high-affinity phosphodiesterase 4 (PDE) inhibitor (IC50: 3.2 pM for PDE4B). It can be used for the treatment of chronic obstructive pulmonary disease.
价 格:¥电议型 号:T11483产 地:中国大陆
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T1148Menbutone;孟布酮Naftobil|||Genabilic acid|||Genabilin;孟布酮|||Naftobil|||Genabilic acid|||Genabilin
Menbutone (Genabilin) is a derivative of oxobutyric acid, and is a choleretic. Menbutone shows a rapid onset of action, reaching its maximum plasma level within 1 hour and lasting for roughly 10 hours.
价 格:¥电议型 号:T1148产 地:中国大陆
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T11478LGSK1521498 free base;化合物 T11478LGSK1521498 free base
GSK1521498 free base is a potent and selective antagonist of the μ-opioid receptor. GSK1521498 free base also has the potential for disorders of compulsive consumption of food, alcohol, and drugs.
价 格:¥电议型 号:T11478L产 地:中国大陆
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T11478GSK1521498 free base (hydrochloride);化合物 T11478GSK1521498 free base (hydrochloride)
GSK1521498 free base (hydrochloride) is a selective antagonist of the μ-opioid receptor (MOR). It is being used for the treatment of disorders of compulsive consumption of food, alcohol, and drugs.
价 格:¥电议型 号:T11478产 地:中国大陆
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T1146Nifedipine;硝苯地平BAY-a-1040|||Procardia XL|||Procardia|||Adalat;BAY-a-1040|||Procardia XL|||Procardia|
Nifedipine (Procardia) is a dihydropyridine calcium channel blocking agent. Nifedipine inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents.
价 格:¥电议型 号:T1146产 地:中国大陆
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T11458GPR40/FFAR1 modulator 1;化合物GPR40/FFAR1 modulator 1GPR40/FFAR1 modulator 1
GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator.
价 格:¥电议型 号:T11458产 地:中国大陆
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T11450Gosogliptin;化合物 T11450PF-00734200|||PF-734200;PF-00734200|||PF-734200
Gosogliptin is a potent and selective dipeptidyl peptidase-IV (DPP-IV) inhibitor.
价 格:¥电议型 号:T11450产 地:中国大陆
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T11449L2Golotimod (TFA) (229305-39-9 free base);化合物 T11449L2SCV 07 (TFA)|||Gamma-D-glutamyl-L-tryptophan (TF
Golotimod TFA (SCV 07 TFA) is an immunomodulatory peptide with antibacterial properties that significantly increases the effectiveness of anti-tuberculosis studies, stimulates thymus and splenocyte proliferation and improves macrophage function. Golotimod TFA has the potential to be used in studies of recurrent genital herpes simplex virus type 2 (HSV-2).
价 格:¥电议型 号:T11449L2产 地:中国大陆
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T11449Golotimod hydrochloride (229305-39-9 free base);化合物 T11449Golotimod hydrochloride|||Gamma-D-glutamyl
Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts macrophage functionality. Furthermore, it inhibits STAT3 signaling, thereby modifying the duration and intensity of oral mucositis in animal models subjected to radiation or a combination of radiation and Cisplatin. Additionally, Golotimod hydrochloride has shown potential as a t
价 格:¥电议型 号:T11449产 地:中国大陆
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T11447GNF4877;化合物GNF4877GNF4877
GNF4877 is a potent DYRK1A and GSK3β inhibitor (IC50s: 6 nM and 16 nM). It leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation cells.
价 格:¥电议型 号:T11447产 地:中国大陆
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T11446GNF362;化合物 T11446GNF362
GNF362 is a selective and orally bioavailable inhibitor of inositol trisphosphate 3’ kinase B (Itpkb; IC50: 9 nM). GNF362 also inhibits Itpka and Itpkc (IC50s: 20 nM and 19 nM).
价 格:¥电议型 号:T11446产 地:中国大陆
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T11445GNF179 (Metabolite);化合物 T11445GNF179 Metabolite;GNF179 Metabolite
GNF179 Metabolite, the derivative of GNF179—an optimized 8,8-dimethyl IP analog—demonstrates significant potency (4.8 nM against the multidrug-resistant W2 strain) alongside in vitro metabolic stability and in vivo oral bioavailability.
价 格:¥电议型 号:T11445产 地:中国大陆
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T11444GNF-6231;化合物GNF-6231GNF-6231
GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blocks Wnt signaling.
价 格:¥电议型 号:T11444产 地:中国大陆
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T11432Glyoxalase I inhibitor free base;化合物 T11432Glyoxalase I inhibitor free base
Glyoxalase I inhibitor (free base), a candidate for anticancer agents, is a potent Glyoxalase I (GLO1) inhibitor.
价 格:¥电议型 号:T11432产 地:中国大陆
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T1141Fenbendazole;芬苯达唑Fenbendazol|||Phenbendasol|||Panacur;Fenbendazol|||苯硫咪唑|||芬苯达唑|||Phenbendasol|||Pan
Fenbendazole (Fenbendazol) is an antinematodal benzimidazole used in veterinary medicine.
价 格:¥电议型 号:T1141产 地:中国大陆
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T11408Orforglipron;奥格列隆LY3502970|||GLP-1 receptor agonist 1;LY3502970|||GLP-1 receptor agonist 1
Orforglipron (LY3502970; GLP-1 receptor agonist 1) is an orally available glucagon-like peptide (GLP-1) receptor agonist for the study of obesity and type 1 diabetes in adults.
价 格:¥电议型 号:T11408产 地:中国大陆
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T11406TT-OAD2 free base;化合物 T11406TT-OAD2 free base
TT-OAD2 free base has the potential for diabetes treatment. TT-OAD2 free base is a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist with an EC50 of 5 nM.
价 格:¥电议型 号:T11406产 地:中国大陆
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T11403LGln-AMS TFA (209543-57-7 free base);化合物 T11403LGln-AMS TFA;Gln-AMS TFA
Gln-AMS(TFA) inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 μM. Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor.
价 格:¥电议型 号:T11403L产 地:中国大陆