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T2P2919(2S,3R,4S)-4-Hydroxyisoleucine(4S)4-羟基异亮氨酸;(4S)-4-Hydroxy-L-isoleucine;Hydroxyisoleucine
4-Hydroxyisoleucine (HIL) from fenugreek (Trigonella foenum-graecum) seeds is a potential insulinotropic (anti-diabetic) and anti-obesity amino acid. HIL stimulates glucose-dependent insulin secretion from pancreatic cells. HIL activates insulin receptor
价 格:¥电议型 号:T2P2919产 地:中国大陆
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T24827SR 16832SR-16832;SR16832
SR 16832 is a dual-site PPARγ inhibitor. It also inhibits the binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent antagonist GW 9662 and T 0070907.
价 格:¥电议型 号:T24827产 地:中国大陆
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T2367SKF-86002SKF86002;SKF 86002
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).
价 格:¥电议型 号:T2367产 地:中国大陆
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T197782-ATHBI1-[5-[(1R,2S,3R)-1,2,3,4-四羟基丁基]-1H-咪唑-2-基]乙酮
2-ATHBI is a S1P lyase inhibitor.
价 格:¥电议型 号:T19778产 地:中国大陆
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T19114LSacubitril-(2S,4S)-IsomerLCZ 696杂质C;(2S,4S)-Sacubitril
Sacubitril-(2S,4S)-Isomer is the isomer of Sacubitril which is a neprilysin inhibitor.
价 格:¥电议型 号:T19114L产 地:中国大陆
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T12302OMDM-1(Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide
OMDM-1 is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor with a Ki of 2.4 μM.
价 格:¥电议型 号:T12302产 地:中国大陆
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T10060(1S,2S,3R)-DT-061(1S,2S,3R)-DT-061
(1S,2S,3R)-DT-061 is an enantiomer of DT-061 which is an orally bioavailable activator of PP2A.
价 格:¥电议型 号:T10060产 地:美洲
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T10097(2S,3S)-E1R(2S,3S)-E1R
(2S,3S)-E1R (Compound 2d) is an enantiomer of E1R. (2R,3R)-E1R is a sigma-1 receptor positive allosteric modulator for the treatment of cognition/memory disorders.
价 格:¥电议型 号:T10097产 地:美洲
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T12846SB-423562SB-423562
SB-423562 is a short-acting antagonist of calcium-sensing receptor (CaR).
价 格:¥电议型 号:T12846产 地:美洲
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T12854SBI-797812SBI-797812
SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).
价 格:¥电议型 号:T12854产 地:美洲
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T12873SDZ-MKS 492SDZ-MKS 492,MKS 492,
SDZ-MKS 492 is a selective type III isozyme cyclic nucleotide phosphodiesterase inhibitor.
价 格:¥电议型 号:T12873产 地:美洲
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T12911Sigma-1 receptor antagonist 2Sigma-1 receptor antagonist 2
Sigma-1 receptor antagonist 2 is a potent and selective antagonist of sigma 1 receptor (σ1 R) (σ1 and σ2 receptor with Kis of 3.88 and 1288 nM , respectively).
价 格:¥电议型 号:T12911产 地:美洲
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T12934SMAP-2SMAP-2,DT-1154,
SMAP-2 is an orally bioavailable activator of phosphatase 2A (PP2A) which binds to the PP2A Aα scaffold subunit to drive conformational changes in PP2A. It inhibits the growth of KRAS-mutant lung cancers .
价 格:¥电议型 号:T12934产 地:美洲
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T12941SN 2SN 2
SN 2 is a novel and potent TRPML3 ion channel activator(EC50 of 1.8±0.13 μM).
价 格:¥电议型 号:T12941产 地:美洲
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T13424(1R,2S)-VU0155041(1R,2S)-VU0155041
(1R,2S)-VU0155041 is a partial agonist of mGluR4(EC50 of 2.35 μM).
价 格:¥电议型 号:T13424产 地:美洲
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T16836SAFit2SAFit2
SAFit2 is a highly potent and selective FK506-binding protein 51 inhibitor (Ki: 6 nM) and also enhances AKT2-AS160 binding.
价 格:¥电议型 号:T16836产 地:美洲
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T1726SB 431542SB 431542
SB-431542 is a potent and selective inhibitor of ALK5 (IC50: 94 nM) and is also an inhibitor of ALK4 (IC50: 140 nM) and ALK7.
价 格:¥电议型 号:T1726产 地:美洲
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T19114(2S,4S)-Sacubitril(2S,4S)-Sacubitril
(2S,4S)-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.
价 格:¥电议型 号:T19114产 地:美洲
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T1955SB225002SB225002
SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.
价 格:¥电议型 号:T1955产 地:美洲
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T19612(2S)-Octyl-α-hydroxyglutarate(2S)-Octyl-α-hydroxyglutarate,(2S)-Octyl-2-HG,
(2S)-Octyl-α-hydroxyglutarate ((2S)-Octyl-2-HG) is a S-isomer 2-Hydroxyglutarate modified form.
价 格:¥电议型 号:T19612产 地:美洲