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T2367SKF-86002SKF-86002,SKF86002,SKF 86002
SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).
价 格:¥电议型 号:T2367产 地:美洲
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T2421SKLB1002SKLB1002
SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM.
价 格:¥电议型 号:T2421产 地:美洲
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T4662SJ000291942SJ000291942
SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway. BMPs are members of the transforming growth factor beta (TGFβ) family of secreted signaling molecules.
价 格:¥电议型 号:T4662产 地:美洲
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T4856Nα-Acetyl-L-lysineNα-Acetyl-L-lysine,(2S)-2-Acetamido-6-aminohexanoic acid,
N-Alpha-acetyllysine is a N-acetylated amino acid. It is a normal constituent of human urine with concentrations in normal samples too small to allow its routine detection; however, it has been found at increased levels in the urine of a patient with amin
价 格:¥电议型 号:T4856产 地:美洲
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T4866L-Tryptophanamide hydrochlorideL-Tryptophanamide hydrochloride,(2S)-2-amino-3-(1H-indol-3-yl)propana
Tryptophanamide belongs to the class of organic compounds known as tryptamines and derivatives. Tryptophanamide has been detected in multiple biofluids, such as urine and blood.
价 格:¥电议型 号:T4866产 地:美洲
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T5048SSR240612SSR240612
SSR240612 is a potent, and orally active specific non-peptide bradykinin B1 receptor antagonist (Kis = 0.48-0.73 and 358-481 nM for B1 and B2 receptors, respectively).
价 格:¥电议型 号:T5048产 地:美洲
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T6049SNS-032SNS-032,SNS032,SNS 032
SNS-032 is a selective inhibitor of CDK2 (IC50: 48 nM ) and is 10- and 20-fold selective over CDK1/CDK4. It is also sensitive to CDK7/9 (IC50: 62 nM/4 nM), and no effect on CDK6.
价 格:¥电议型 号:T6049产 地:美洲
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T6305SNX-2112SNX-2112,SNX2112,SNX 2112
SNX-2112 is an orally active Hsp90 inhibitor, with a Kd of 16 nM.
价 格:¥电议型 号:T6305产 地:美洲
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T8792SMBA1;化合物 T8792SMBA1
SMBA1 is a Bax activator and a potent Bax agonist (Ki : 43.3 nM) that induces cell cycle arrest and apoptosis in malignant glioma cells.SMBA1 has shown antitumor activity by enhancing Bax expression.SMBA1 can be used in cancer research.
价 格:¥电议型 号:T8792产 地:中国大陆
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T8497SX-682;化合物SX-682SX-682
SX-682 is a potent, selective and orally bioavailable inhibitor of CXCR1/2 ,has the potential to treat castration-resistant prostate cancer.
价 格:¥电议型 号:T8497产 地:中国大陆
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T83887SLU-10482;化合物 SLU-10482SLU-10482
SLU-10482, an antiparasitic agent, effectively reduces C. parvum parasitic load in HCT-8 cells with an EC50 value of 0.07 ?M. It exhibits lower affinity for human ether-a-go-go (hERG; Kd = 43 ?M) compared to its counterpart, SLU-2633. When administered in vivo at dosages of 5 and 15 mg/kg twice daily, SLU-10482 significantly decreases fecal oocyst counts in mice infected with C. parvum.
价 格:¥电议型 号:T83887产 地:中国大陆
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T83874S-72;化合物 S-72S-72
S-72 acts as a microtubule polymerization inhibitor, effective in cell-free assays at concentrations of 1, 3, and 10 ?M. At nanomolar levels (IC50s = 15.64 and 26.32 nM, respectively), it diminishes the viability of both MCF-7 and paclitaxel-resistant MCF-7/T breast cancer cells. Moreover, at 50 nM, S-72 impedes migration, invasion, and wound healing in these cell lines. Additionally, at 100 nM, it arrests the cell cycle at the G2/M phase and induces apoptosis in MCF-7/T cells, while also inhibi
价 格:¥电议型 号:T83874产 地:中国大陆
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T83616SEW06622;化合物 SEW06622SEW06622
SEW06622 is a potent inhibitor of acetylcholinesterase (AChE) and beta-secretase-1 (BACE-1) and is a potential candidate for the treatment of Alzheimer´s disease.
价 格:¥电议型 号:T83616产 地:中国大陆
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T83560(2S)-5-Methoxyflavan-7-ol;化合物 (2S)-5-Methoxyflavan-7-ol(2S)-5-Methoxyflavan-7-ol
(2S)-5-Methoxyflavan-7-ol (compound 2) is a natural product isolated from Dragon´s blood resin [1].
价 格:¥电议型 号:T83560产 地:中国大陆
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T833852H-1-Benzopyran-2-one, 6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy-;化合物 2H-1-Benzopy
The compound 6-[(1R,2S)-2,3-dihydroxy-1-methoxy-3-methylbutyl]-7-methoxy has been isolated from the stem of Angelica dahurica, marking its first discovery from a plant source [1].
价 格:¥电议型 号:T83385产 地:中国大陆
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T81224SALMF amide 2;化合物 SALMF amide 2SALMF amide 2
SALMFamide 2, a neuropeptide S2 derived from the starfish Asterias rubens, plays a regulatory role in the eversion of the cardiac stomach in starfish [1].
价 格:¥电议型 号:T81224产 地:中国大陆
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T81210SARS-CoV-2 Mpro-IN-12;化合物 SARS-CoV-2 Mpro-IN-12SARS-CoV-2 Mpro-IN-12
SARS-CoV-2 Mpro-IN-12 (compound D026) serves as an inhibitor of the main protease (Mpro) of SARS-CoV-2, exhibiting antiviral properties [1].
价 格:¥电议型 号:T81210产 地:中国大陆
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T81209SARS-CoV-2-IN-62;化合物 SARS-CoV-2-IN-62SARS-CoV-2-IN-62
SARS-CoV-2-IN-62 (Compound R3b) effectively inhibits SARS-CoV-2 replication in Vero E6 and Calu-3 cells, demonstrating low cytotoxicity and EC50 values of 2.97 μM and 3.82 μM, respectively [1].
价 格:¥电议型 号:T81209产 地:中国大陆
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T81198SBP-2;化合物 SBP-2SBP-2
SBP-2, a sulfite bioluminescent probe (SBP), detects sulfite through a mechanism involving sulfite-mediated intramolecular cleavage [1].
价 格:¥电议型 号:T81198产 地:中国大陆
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T81176Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2;化合物 Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2Ser-parafluor
Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biologically active peptide. Structure-activity studies of the thrombin receptor-tethered ligand SFLLRNP underscored the pivotal role of the Phe-2-phenyl group in receptor recognition, while substitution with para-fluorophenylalanine [(p-F)Phe] augmented its activity.
价 格:¥电议型 号:T81176产 地:中国大陆