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产品数:86101
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已选条件
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T7880IOX4IOX 4,HIF-PH,HIFs,Hypoxia-inducible factors,IOX4,IOX-4,inhibit,HIF/HIF Prolyl-Hydroxylase,Inhibi
IOX4 is a potent PHD2 inhibitor (IC50 = 1.6 nM)
价 格:¥电议型 号:T7880产 地:中国大陆
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T94734SC-203tumor,antineoplastic,Fms like tyrosine kinase 3,Vascular endothelial growth factor receptor,4
4SC-203 is a multikinase inhibitor with potential antineoplastic activity. 4SC-203 selectively inhibits FMS-related tyrosine kinase 3 (FLT3/STK1), FLT3 mutated forms, and vascular endothelial growth factor receptors (VEGFRs).
价 格:¥电议型 号:T9473产 地:中国大陆
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T6918OlmutinibOlmutinib,ErbB-1,inhibit,HER1,EGFR,Epidermal growth factor receptor,Inhibitor
Olmutinib is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild-type form.
价 格:¥电议型 号:T6918产 地:中国大陆
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TN2244Sulfuretininflammation,platelet,Allergic,Sulfuretin,Nuclear factor-kappaB,Airway,Inhibitor,aggregati
Sulfuretin is a potent anti-oxidant, has protective effect against t-BHP-induced oxidative damage in human liver-derived HepG2 cells is attributable to its ability to scavenge ROS and up-regulate the activity of HO-1 through the Nrf2/ARE and JNK/ERK signaling pathways.
价 格:¥电议型 号:TN2244产 地:中国大陆
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T9724WAY-340935Inhibitor,WAY340935,Vascular endothelial growth factor receptor,WAY 340935,inhibit,VEGFR,A
WAY-340935 has anti-inflammatory and analgesic activities.
价 格:¥电议型 号:T9724产 地:中国大陆
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T7861Flumatinib mesylateHHGV-678,PDGFRβ,HHGV678,c-Abl,Bcr-Abl,Platelet-derived growth factor receptor,PDG
Flumatinib mesylate is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.
价 格:¥电议型 号:T7861产 地:中国大陆
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T7175Alflutinib mesylatecancer,Epidermal growth factor receptor,AST2818,esistant mutation,Alflutinib,Alfl
AST2818 mesylate,is an irreversible tyrosine kinase inhibitor that selectively inhibits EGFR mutations, especially T790M.
价 格:¥电议型 号:T7175产 地:中国大陆
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T6S1487Ginsenoside Rg5Nuclear factor-κB,Inhibitor,Ginsenoside Rg5,Cyclooxygenase,Ginsenoside Rg 5,NF-κB,COX
1. Ginsenoside Rg5 could be a beneficial agent for the treatment of Alzheimer´s disease. 2. Ginsenoside Rg5 suppresses LPS-induced nitric oxide (NO) production and proinflammatory TNF-α secretion. 3. Ginsenoside Rg5 can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. 4. Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasc
价 格:¥电议型 号:T6S1487产 地:中国大陆
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T6517GolvatinibE7050,Golvatinib,c-Met/HGFR,VEGFR,Inhibitor,Vascular endothelial growth factor receptor,E
Golvatinib is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. c-Met/VEGFR kinase inhibitor E7050 binds to and inhibits the activities of both c-Met and VEGFR-2, which may inhibit tumor cell growth and survival of tumor cells that overexpress these receptor tyrosine kinases. c-Met and VEGFR-2 are upregulated in a variety of tumor cell types
价 格:¥电议型 号:T6517产 地:中国大陆
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TP1106Lα-Factor Mating Pheromone, yeast acetateα Factor Mating Pheromone, yeast acetate,αFactor Mating Pher
α-Factor Mating Pheromone, yeast acetate is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells.
价 格:¥电议型 号:TP1106L产 地:中国大陆
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T6S1966CurculigosideCurculigoside,Janus kinase,NF-κB,JAK,Nuclear factor-κB,Nuclear factor-kappaB,STAT,inhib
1. Curculigoside can prevent bone loss , improve osteogenesis and inhibit osteoclastogenesis of hAFSCs, suggesting its potential use to regulate hAFSC osteogenic differentiation for treating bone disorders. 2. Curculigoside can promote calcium deposition and increase the levels of ALP and Runx2 in osteoblasts under oxidative stress via anti-oxidative character. 3. Curculigoside possesses potent antioxidant properties against oxidative stress insults. can protect endothelial cells against oxidati
价 格:¥电议型 号:T6S1966产 地:中国大陆
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T7091N-Formyl-Met-Leu-PheTNF Receptor,TNFR,Inhibitor,NFormylMetLeuPhe,Tumor Necrosis Factor Receptor,inhi
N-Formyl-Met-Leu-Phe (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).
价 格:¥电议型 号:T7091产 地:中国大陆
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T7186CZC-8004CZC 8004,HER1,Vascular endothelial growth factor receptor,ErbB-1,Epidermal growth factor rec
CZC-8004 is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.
价 格:¥电议型 号:T7186产 地:中国大陆
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TQ0198Phorbol 12-myristate 13-acetatePKC,SphK,Nuclear factor-κB,Protein kinase C,Inhibitor,Phorbol 12 myri
Phorbol 12-myristate 13-acetate (PMA) is a dual SphK and PKC activator.
价 格:¥电议型 号:TQ0198产 地:中国大陆
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T7945SU14813c-Kit,Inhibitor,VEGFR,Vascular endothelial growth factor receptor,SU 14813,PDGFR,CD117,Platel
SU14813 is a multi-receptor tyrosine kinase inhibitor with potent antiangiogenesis and antitumor activity (IC50s of 50, 2, 4, 15 nM for VEGFR2, VEGFR1, PDGFRβ and KIT).
价 格:¥电议型 号:T7945产 地:中国大陆
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T8492BO-264inhibit,cytotoxicity,antitumor,Fibroblast growth factor receptor,BO-264,Apoptosis,Inhibitor,TA
BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).
价 格:¥电议型 号:T8492产 地:中国大陆
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T8213IsolinderalactoneSurvivin,VEGFR,Isolinderalactone,Vascular endothelial growth factor receptor,Inhibi
Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.
价 格:¥电议型 号:T8213产 地:中国大陆
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TQ018514-Deoxy-11,12-didehydroandrographolideinhibit,Nuclear factor-κB,Inhibitor,14 Deoxy 11,12 didehydroa
14-Deoxy-11,12-didehydroandrographolide has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions. It can inhibit NF-κB activation.
价 格:¥电议型 号:TQ0185产 地:中国大陆
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T6682STF-118804Inhibitor,STF-118804,inhibit,Pre-B cell colony enhancing factor,Apoptosis,Nicotinamide pho
STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.
价 格:¥电议型 号:T6682产 地:中国大陆
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T8431JCN037JCN037,Epidermal growth factor receptor,HER1,Inhibitor,JCN-037,JCN 037,inhibit,EGFR,JGK-037,Er
JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).
价 格:¥电议型 号:T8431产 地:中国大陆