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T11285FIDAS-5;化合物FIDAS-5FIDAS-5
FIDAS-5, a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM, competitively inhibits S-adenosylmethionine (SAM) binding to MAT2A. It exhibits anticancer activities.
价 格:¥电议型 号:T11285产 地:中国大陆
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T11284FIDAS-3;化合物FIDAS-3FIDAS-3
FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for MAT2A binding.
价 格:¥电议型 号:T11284产 地:中国大陆
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T11283Fibracillin;非布拉西林Fibracillin
Fibracillin is a penicillin antibiotic.
价 格:¥电议型 号:T11283产 地:中国大陆
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T11282LFGTI-2734 mesylate (1247018-19-4 free base);化合物 T11282LFGTI-2734 mesylate;FGTI-2734 mesylate
FGTI-2734 mesylate, a RAS C-terminal mimetic compound with dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitory activities (IC50s of 250 nM and 520 nM for FT and GGT, respectively), mitigates KRAS resistance by preventing its membrane localization, effectively impeding mutant KRAS patient-derived pancreatic tumors.
价 格:¥电议型 号:T11282L产 地:中国大陆
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T11282FGTI-2734;化合物FGTI-2734FGTI-2734
FGTI-2734 is a dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT-1) inhibitor, exhibiting IC50 values of 250 nM and 520 nM for FT and GGT-1, respectively. It effectively prevents the membrane localization of KRAS, addressing the issue of KRAS resistance and inhibiting the growth of mutant KRAS patient-derived pancreatic tumors.
价 格:¥电议型 号:T11282产 地:中国大陆
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T11281LFGI-106 tetrahydrochloride;化合物FGI-106 tetrahydrochlorideFGI-106 tetrahydrochloride
FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola, Rift Valley, and Dengue Fever, with half-maximal effective concentrations (EC50s) of 100 nM, 800 nM, and 400-900 nM, respectively. Additionally, it effectively inhibits non-hemorrhagic fever viruses, notably HCV and HIV-1, with EC50s of 200 nM and 150 nM, respectively, indicating its broad-spectrum antiviral potential.
价 格:¥电议型 号:T11281L产 地:中国大陆
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T11281FGI-106;化合物 T11281FGI-106
FGI-106 is a potent, broad-spectrum inhibitor demonstrating activity against various viruses, including Ebola, Rift Valley Fever, and Dengue Fever, exhibiting EC50 values of 100 nM, 800 nM, and 400-900 nM, respectively. Furthermore, it effectively inhibits non-hemorrhagic fever viruses such as HCV and HIV-1, with EC50s of 200 nM and 150 nM, respectively.
价 格:¥电议型 号:T11281产 地:中国大陆
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T11280FGFR4-IN-4;化合物 T11280FGFR4-IN-4
FGFR4-IN-4 is a FGFR4 inhibitor with anti-tumor activity.
价 格:¥电议型 号:T11280产 地:中国大陆
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T1128Oxiracetam;奥拉西坦ISF2522;奥拉西坦|||ISF2522
Oxiracetam (ISF2522), a cyclic derivative of gamma-aminobutyric acid (GABA), is utilized for the treatment of cognitive impairments.
价 格:¥电议型 号:T1128产 地:中国大陆
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T11279FGFR1/DDR2 inhibitor 1;化合物FGFR1/DDR2 inhibitor 1FGFR1/DDR2 inhibitor 1
FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.
价 格:¥电议型 号:T11279产 地:中国大陆
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T11278FG8119;化合物FG8119NNC13-8119;NNC13-8119
FG8119 is a novel benzodiazepine agonist with potential anticonvulsant and antiepileptic activity for the study of neurological disorders.
价 格:¥电议型 号:T11278产 地:中国大陆
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T11277FG 7142;化合物FG 7142ZK 39106|||LSU-65;ZK 39106|||LSU-65
FG 7142 (LSU-65) also modulates GABA-induced chloride flux at GABAA receptors expressing the α1 subunit (EC50= 137 nM). FG 7142 can increase tyrosine hydroxylation and cause upregulation of β-adrenoceptors in mouse cerebral cortex. FG 7142 , a non-selectively benzodiazepine inverse agonist, has high affinity for the α1 subunit-containing GABAA receptor (Ki=91 nM).
价 格:¥电议型 号:T11277产 地:中国大陆
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T11276Fexofenadine-d6;非索非那定 d6MDL-16455-d6|||Terfenadine carboxylate-d6;MDL-16455-d6|||Terfenadine carboxy
Fexofenadine-d6 (MDL-16455-d6) is the deuterium substituent of Fexofenadine and can be used as an internal standard for the determination of non-sofenadine concentrations in human plasma.
价 格:¥电议型 号:T11276产 地:中国大陆
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T11275Fesoterodine L-mandelate;非索罗定扁桃酸盐Fesoterodine L-mandelate
Fesoterodine L-mandelate is a efficacious antimuscarinic agent for the overactive bladder (OAB).
价 格:¥电议型 号:T11275产 地:中国大陆
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T11273Fenpiverinium D3 bromide;化合物 T11273Fenpiverinium D3 bromide
Fenpiverinium bromide has anti-cholinergic and anti-spasmodic effects.Fenpiverinium D3 bromide is a deuterium labeled Fenpiverinium bromide.
价 格:¥电议型 号:T11273产 地:中国大陆
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T11272Fenmetozole Tosylate;化合物 T11272Fenmetozole Tosylate
Fenmetozole Tosylate , acts as an antidepressant drug. is an antagonist of the actions of ethanol, also antagonizes α2-adrenergic receptor,
价 格:¥电议型 号:T11272产 地:中国大陆
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T11271Fenclozine;化合物 T11271Fenclozine
Fenclozine is a non-steroidal antiinflammatory drug.
价 格:¥电议型 号:T11271产 地:中国大陆
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T11269FD-IN-1;化合物 T11269FD-IN-1
FD-IN-1 is a factor D (FD) inhibitor with an IC50 of 12 nM.FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5μM, respectively. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system.
价 格:¥电议型 号:T11269产 地:中国大陆
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T11268FD 12-9;化合物 T11268Ac12Az9;Ac12Az9
FD 12-9, Anti-glioblastoma activity. is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively.
价 格:¥电议型 号:T11268产 地:中国大陆
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T11267FASN-IN-1;化合物FASN-IN-1TVB-2460;TVB-2460
FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme involved in fatty acid synthesis, potentially disrupting fatty acid production and affecting various cellular processes.
价 格:¥电议型 号:T11267产 地:中国大陆