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T10595LBQ-788 sodium salt;化合物 T10595LBQ-788 sodium salt
BQ-788 sodium salt is a potent and selective antagonist of ETB receptor(ETB receptors with an IC50 of 1.2 nM in human Girrardi heart cells).
价 格:¥电议型 号:T10595L产 地:中国大陆
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T10591L(R)-BPO-27;化合物(R)-BPO-27(R)-BPO-27
(R)-BPO-27 is an orally active and potent ATP-competitive CFTR inhibitor (IC50: 4 nM) for the study of diarrhoea and polycystic kidney.
价 格:¥电议型 号:T10591L产 地:中国大陆
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T1059Retinyl palmitate;维生素A棕榈酸酯Retinol palmitate|||Vitamin A palmitate|||Retinyl (Vitamin A) Palmitate;Re
Retinyl palmitate (Vitamin A palmitate) is a naturally-occurring phenyl analogue of retinol, with potential antineoplastic and chemopreventive activities.
价 格:¥电议型 号:T1059产 地:中国大陆
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T10589LBPN-15606;化合物 T10589LBPN-15606
BPN-15606, an orally active γ-secretase modulator (GSM), significantly reduces Aβ42 and Aβ40 production in SHSY5Y neuroblastoma cells, demonstrating IC50 values of 7 nM and 17 nM, respectively. This compound exhibits favorable pharmacokinetic/pharmacodynamic (PK/PD) properties, such as bioavailability, half-life, and clearance. Importantly, BPN-15606 markedly decreases Aβ42 and Aβ40 levels in the central nervous system of both rats and mice[1].
价 格:¥电议型 号:T10589L产 地:中国大陆
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T10589BPN-15606 besylate (1914989-49-3 free base);化合物 T10589BPN-15606 besylate;BPN-15606 besylate
BPN-15606 besylate is a highly potent, orally active γ-secretase modulator, attenuates the production of Aβ40 and Aβ42 by SHSY5Y neuroblastoma cells (IC50s: 7 nM and 17nM).
价 格:¥电议型 号:T10589产 地:中国大陆
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T10586LBPH-1358;化合物BPH-1358NSC50460;NSC50460
BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. aureus in vitro (MIC ~250 ng/mL)[1][2].
价 格:¥电议型 号:T10586L产 地:中国大陆
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T10579BO3482;化合物 T10579BO3482
BO3482 is an antimicrobial compound and can inhibit the growth of methicillin-resistant Staphylococci (MIC90: 6.25 mg/mL).
价 格:¥电议型 号:T10579产 地:中国大陆
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T10572LBMT-124110 Formate;BMT-124110甲酸盐BMT-124110 Formate(1679371-59-5 Free base);BMT-124110 Formate(167937
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase BIKE with an IC50: 17 nM.BMT-124110 Formate inhibits the cell-cycle protein G-related BMT-124110 Formate inhibits the cell cycle protein G-associated kinase GAK with an IC50:99 nM.
价 格:¥电议型 号:T10572L产 地:中国大陆
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T10569BMS-654457;化合物 T10569BMS-654457
BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).
价 格:¥电议型 号:T10569产 地:中国大陆
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T10563LBM635 hydrochloride (1493762-74-5 free base);化合物 T10563LBM635 hydrochloride;BM635 hydrochloride
BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).
价 格:¥电议型 号:T10563L产 地:中国大陆
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T10559Blonanserin D8;化合物 T10559AD-5423 D8;AD-5423 D8
Blonanserin D8 is a deuterium-labeled Blonanserin. Blonanserin (AD-5423) is a dopamine D2/5-HT2 receptor antagonist with an atypical antipsychotic effect.
价 格:¥电议型 号:T10559产 地:中国大陆
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T10556BKI-1369;化合物 T10556BKI-1369
BKI-1369 is a bumped kinase inhibitor. BKI-1369 increases hERG-inhibitory activity (IC50:1.52 μM).
价 格:¥电议型 号:T10556产 地:中国大陆
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T10549Bisindolylmaleimide VIII acetate;化合物Bisindolylmaleimide VIII acetateRo 31-7549 acetate|||Bis VIII ac
Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC). It has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively.
价 格:¥电议型 号:T10549产 地:中国大陆
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T10540BIBP3226 TFA;化合物 T10540BIBP3226 TFA
BIBP3226 TFA is an effective and selective antagonist of neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor (Kis: 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF).
价 格:¥电议型 号:T10540产 地:中国大陆
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T10539BIBO3304 TFA;化合物BIBO3304 TFABIBO3304 TFA
BIBO3304 TFA is an effective, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist (IC50:0.38 and 0.72 nM for the human and the rat Y1 receptor).
价 格:¥电议型 号:T10539产 地:中国大陆
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T10538LBI-9321 trihydrochloride;化合物 T10538LBI-9321 trihydrochloride
BI-9321 trihydrochloride is a selective and cellular active nuclear receptor-binding SET domain 3 (NSD3)-PWWP1 domain antagonist (Kd: 166 nM). BI-9321 is inactive against NSD2-PWWP1 and NSD3-PWWP2.
价 格:¥电议型 号:T10538L产 地:中国大陆
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T10535LBI 653048 phosphate;化合物 T10535LBI 653048 phosphate
BI 653048 phosphate is a selective and orally active agonist of nonsteroidal glucocorticoid (GC)(IC50 : 55 nM).
价 格:¥电议型 号:T10535L产 地:中国大陆
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T10529BF-168化合物 T10529BF168|||BF 168
BF-168 is a candidate probe for PET and specifically recognizes both neuritic and diffuse plaques (Ki: 6.4 nM for Aβ1-42).
价 格:¥电议型 号:T10529产 地:中国大陆
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T10509Xanthine oxidase-IN-1;黄嘌呤氧化酶IN14-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid;4-(3-Cyano-5
Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid and nucleotide intermediates.
价 格:¥电议型 号:T10509产 地:中国大陆
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T1049LOxybutynin;奥昔布宁Oxytrol|||Ditropan|||Oxibutyninum;Oxytrol|||奥昔布宁|||Ditropan|||Oxibutyninum
Oxybutynin (Ditropan) is a synthetic anticholinergic agent that is used for treatment of urinary incontinence and overactive bladder syndrome.
价 格:¥电议型 号:T1049L产 地:中国大陆