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T10302Amibegron hydrochloride;化合物 T10302SR 58611A;SR 58611A
Amibegron hydrochloride is a selective β3-adrenoceptor agonist (EC50: 3.5 nM for β-adrenoceptor in rat colon). It has anxiolytic and antidepressant activity.
价 格:¥电议型 号:T10302产 地:中国大陆
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T10299AMG PERK 44;化合物 AMG PERK 44AMG PERK 44
AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) that induces autophagy.AMG PERK 44 inhibits GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM) and can be used in the study of cancer.
价 格:¥电议型 号:T10299产 地:中国大陆
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T10298LAMG-548;化合物 T10298LAMG-548
AMG-548 is an orally active and selective p38α inhibitor (Ki=0.5 nM), shows slightly selective over p38β (Ki=36 nM) and >1000 fold selective against p38γ and p38δ and is also extremely potent in the inhibition of whole blood LPS stimulated TNFα (IC50=3 nM)[1]. AMG-548 inhibits Wnt signaling by directly inhibiting Casein kinase 1 isoforms δ and ε[2].
价 格:¥电议型 号:T10298L产 地:中国大陆
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T10297LAMG 487;化合物AMG 487AMG 487
AMG 487 is a potent and selective antagonist of chemokine (C-X-C motif) receptor 3 (CXCR3) which inhibits the binding of CXCL10 and CXCL11 to CXCR3 with IC50s of 8.0 and 8.2 nM, respectively.
价 格:¥电议型 号:T10297L产 地:中国大陆
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T10290LAlpertine HCl;阿尔哌汀盐酸盐Win 31665 HCl|||Alpertine HCl(27076-46-6 Free base);Win 31665 HCl|||Alpertine H
Alpertine HCl is a small molecule compound with anti-neuropathic properties.
价 格:¥电议型 号:T10290L产 地:中国大陆
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T1029Aztreonam;氨曲南SQ-26,776;SQ-26,776|||氨曲南
Aztreonam (SQ-26,776) is a monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum with bactericidal activity.
价 格:¥电议型 号:T1029产 地:中国大陆
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T10289Alosetron ((Z)-2-butenedioate);马来酸阿洛司琼GR 68755 ((Z)-2-butenedioate)|||GR 68755X ((Z)-2-butenedioate)
Alosetron (GR 68755) (Z)-2-butenedioate is a Serotonin 5HT3-receptor antagonist that is used in the treatment of irritable bowel syndrome.
价 格:¥电议型 号:T10289产 地:中国大陆
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T10279Alfacalcidol-D6;化合物 T10279Alfacalcidol-D6
Alfacalcidol-D6 is a deuterated Alfacalcidol. Alfacalcidol is a non-selective VDR activator medication.
价 格:¥电议型 号:T10279产 地:中国大陆
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T10276LAKT Kinase Inhibitor HCl;AKT Kinase抑制剂盐酸盐AKT Kinase Inhibitor HCl(842148-40-7 Free base);AKT Kinase
AKT Kinase Inhibitor HCl is an Akt inhibitor with antitumor activity.
价 格:¥电议型 号:T10276L产 地:中国大陆
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T1027Luteolin;木犀草素Luteolol|||Flacitran|||Digitoflavone|||Luteoline;木犀草素|||Luteolol|||Flacitran|||Digitofl
Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor. Luteolin has a wide range of biological activities including antitumor, antioxidant, anti-inflammatory, antimicrobial, antiviral, antiallergic, and procoagulant.
价 格:¥电议型 号:T1027产 地:中国大陆
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T10269AHR antagonist 2;AHR拮抗剂2AHR antagonist 2
AHR antagonist 2 is an antagonist of the aryl hydrocarbon receptor. The IC50s for human AHR and mouse AHR are 0.885 and 2.03 nM, respectively.
价 格:¥电议型 号:T10269产 地:中国大陆
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T10267Agomelatine (L(+)-Tartaric acid);阿戈美拉汀 L(+)-酒石酸S-20098 L(+)-Tartaric acid;阿戈美拉汀 L(+)-酒石酸|||S-20098 L
Agomelatine (S-20098) L(+)-Tartaric acid is a specific agonist of MT1 and MT2 receptors (Kis: 0.1, 0.06, 0.12, and 0.27 nM for CHO-hMT1, HEK-hMT1, CHO-hMT2, and HEK-hMT2). It also is a selective 5-HT2C receptor antagonist (pKis: 6.4 and 6.2 at native (porcine) and cloned (human) 5-HT2C receptors).
价 格:¥电议型 号:T10267产 地:中国大陆
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T10259AGI-25696;化合物AGI-25696AGI-25696
AGI-25696 is an inhibitor of methionine adenosyltransferase 2A (MATA2). AGI-25696 blocks the growth of MTAP-deleted tumors in vivo and can be used for studies about the treatment of cancer.
价 格:¥电议型 号:T10259产 地:中国大陆
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T10252L2ADU-S100 ammonium salt;化合物ADU-S100 ammonium saltML RR-S2 CDA ammonium salt|||MIW815 ammonium salt;ML
ADU-S100 ammonium salt (ML RR-S2 CDA ammonium salt) is an activator of stimulator of interferon genes (STING). ADU-S100 ammonium salt leads to potent and systemic tumor regression and immunity.
价 格:¥电议型 号:T10252L2产 地:中国大陆
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T10252LADU-S100 enantiomer ammonium salt;化合物 T10252LMIW815 enantiomer ammonium salt|||ML RR-S2 CDA enantiom
ADU-S100 (MIW815) enantiomer ammonium salt is the less active enantiomer of ADU-S100. ADU-S100 is an activator of the stimulator of interferon genes (STING).
价 格:¥电议型 号:T10252L产 地:中国大陆
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T10251Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA;化合物 T10251ACTH (1-39) (mouse, rat) TFA;ACTH (1-39
Adrenocorticotropic Hormone (ACTH) (1-39), rat (TFA) is a potent melanocortin 2 receptor (MC2) agonist.
价 格:¥电议型 号:T10251产 地:中国大陆
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T1025Tranylcypromine (2-PCPA) hydrochloride反苯环丙胺盐酸盐反苯环丙胺盐酸盐|||Tranylcypromine (2-PCPA) HCl|||SKF-385 HCl
Tranylcypromine (2-PCPA) hydrochloride (SKF-385 HCl), a Monoamine Oxidase inhibitor, is effective in the treatment of major depression, dysthymic disorder, and atypical depression.
价 格:¥电议型 号:T1025产 地:中国大陆
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T10249Adoprazine;阿哆嗪SLV313;SLV313
Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.
价 格:¥电议型 号:T10249产 地:中国大陆
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T10242ACT-389949;化合物ACT-389949ACT-389949
ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)/Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2/ALX internalization into monocytes. It has the potential for the treatment of inflammatory disorders.
价 格:¥电议型 号:T10242产 地:中国大陆
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T10239Acolbifene;阿考比芬EM-652|||SCH 57068;阿考比芬|||EM-652|||SCH 57068
Acolbifene (SCH 57068) is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERα and ERβ. Acolbifene shows an anticarcinogenic property.
价 格:¥电议型 号:T10239产 地:中国大陆