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T10499H3 receptor-MO-1;H3 受体调节剂1H3 receptor-MO-1
H3 receptor-MO-1 is a potent modulator of the histamine H3 receptor (H3 receptor) and can be used to study neurodegeneration and cognitive disorders.
价 格:¥电议型 号:T10499产 地:中国大陆
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T10495LBefiradol化合物 T10495LNLX-112|||F13640
Befiradol (NLX-112) is an agonist of 5-HT1A receptor.
价 格:¥电议型 号:T10495L产 地:中国大陆
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T10491LGalidesivir hydrochloride;化合物 T10491LBCX 4430 hydrochloride|||Immucillin-A hydrochloride;BCX 4430 hy
Galidesivir hydrochloride is an inhibitor of viral RNA-dependent RNA polymerase (RdRp). It inhibits SARS-CoV-2 by tightly binding to its RdRp.
价 格:¥电议型 号:T10491L产 地:中国大陆
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T10491Galidesivir;加利司韦BCX4430|||Immucillin-A;BCX4430|||Immucillin-A
Galidesivir (BCX4430) is a broad-spectrum antiviral compound, an adenosine analog that inhibits viral RNA-dependent RNA polymerase (RdRp) activity.Galidesivir inhibits a wide range of RNA viral pathogens in vitro, and reduces lung infections in infected animals.
价 格:¥电议型 号:T10491产 地:中国大陆
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T1049Oxybutynin chloride;盐酸奥昔布宁Oxybutynin hydrochloride|||Oxybutynin HCl;Oxybutynin hydrochloride|||盐酸奥昔布
Oxybutynin chloride (Oxybutynin HCl) is an anticholinergic medication used to relieve urinary and bladder difficulties. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor.
价 格:¥电议型 号:T1049产 地:中国大陆
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T10489BCR-ABL-IN-2;化合物 T10489BCR-ABL-IN-2
BCR-ABL-IN-2 is a BCR-ABL1 tyrosine kinase inhibitor (IC50s: 57 nM, 773 nM for ABL1 native and ABL1 T315I).
价 格:¥电议型 号:T10489产 地:中国大陆
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T10486LBCI hydrochloride化合物 T10486L(E)-BCI hydrochloride
BCI hydrochloride specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively. BCI hydrochloride does not inhibit DUSP5. BCI hydrochloride is an allosteric inhibitor of dual specificity phosphatase (DUSP).
价 格:¥电议型 号:T10486L产 地:中国大陆
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T10482LBB-Cl-Amidine hydrochloride化合物 T10482LBB-Cl-Amidine hydrochloride (1802637-39-3 free base)
BB-Cl-Amidine hydrochloride is an inhibitor of peptidylarginine deminase (PAD) [1].
价 格:¥电议型 号:T10482L产 地:中国大陆
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T10481LBAY 73-6691;化合物 T10481L(R)-BAY 73-6691;(R)-BAY 73-6691
BAY 73-6691 is an inhibitor of brain penetrant PDE9A.
价 格:¥电议型 号:T10481L产 地:中国大陆
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T10480LBay 41-4109;化合物 T10480LBay 41-4109
BAY 41-4109 is a potent inhibitor of human hepatitis B virus (HBV)(IC50 : 53 nM).
价 格:¥电议型 号:T10480L产 地:中国大陆
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T1048Estradiol;雌二醇E2|||17β-Estradiol|||17β-Oestradiol|||β-Estradiol;雌二醇|||E2|||17β-Estradiol|||17β-Oestra
Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics. Estradiol upregulates IL-6 expression through estrogen receptor beta (ERβ).
价 格:¥电议型 号:T1048产 地:中国大陆
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T10476BAY-899;化合物 T10476BAY-899
BAY-899 is an orally active and selective antagonist of the luteinizing hormone receptor (LH-R), exhibiting IC50 values of 185 nM and 46 nM for human LH (hLH) and rat LH (rLH) respectively. In vivo studies have demonstrated that BAY-899 effectively reduces sex hormone levels[1].
价 格:¥电议型 号:T10476产 地:中国大陆
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T10473LBAY-677;化合物 T10473LBAY-677
BAY-677, serving as an inactive control for BAY-678, is distinguished by BAY-678´s capabilities as an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE), showcasing a high potency with an IC50 of 20 nM[1]. Furthermore, BAY-678 has been publicly nominated as a chemical probe by the Structural Genomics Consortium (SGC)[2].
价 格:¥电议型 号:T10473L产 地:中国大陆
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T10472LBay 65-1942 free base;化合物 T10472LBay 65-1942 free base
Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.
价 格:¥电议型 号:T10472L产 地:中国大陆
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T10469BAY-298;化合物 T10469BAY-298
BAY-298 is an orally active and selective luteinizing hormone receptor (LH-R) antagonist with IC 50 s of 96 nM, 23 nM and 78 nM for hLH (human LH) and rLH (rat LH) and cLH (cynomolgus monkey LH), respectively. BAY-298 is the first nanomolar hLH-R antagonist reducing sex hormone levels in vivo[1].
价 格:¥电议型 号:T10469产 地:中国大陆
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T10464LAtuveciclib Racemate;阿维西利BAY-1143572 Racemate;BAY-1143572 Racemate|||阿维西利
Atuveciclib Racemate (BAY-1143572 Racemate) is the racemate mixture of Atuveciclib, which is a potent and highly selective, oral P-TEFb/CDK9 inhibitor which supresses CDK9/CycT1 with an IC50 of 13 nM.
价 格:¥电议型 号:T10464L产 地:中国大陆
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T10463LBax inhibitor peptide V5 acetate;化合物T10463LBax inhibitor peptide V5 acetate(579492-81-2 free base);B
Bax inhibitor peptide V5 acetate (Bax inhibitor peptide V5 acetate(579492-81-2 free base)) is a Bax-mediated apoptosis inhibitor, used for cancer treatment.
价 格:¥电议型 号:T10463L产 地:中国大陆
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T10462LBavisant dihydrochloride hydrate;化合物 T10462LJNJ31001074AAC;JNJ31001074AAC
Bavisant dihydrochloride hydrate (JNJ31001074AAC) is a highly selective, orally active antagonist of the human H3 receptor with a novel mechanism of action, involving wakefulness and cognition, with potential as a treatment for ADHD. in vivo: Mean change from baseline in the total ADHD-RS-IV score at day 42 (primary efficacy endpoint) was -8.8 in the placebo group versus -9.3, -11.2 and -12.2 in the bavisant 1 mg/day, 3 mg/day and 10 mg/day groups, respectively; the change in the 10 mg/day group
价 格:¥电议型 号:T10462L产 地:中国大陆
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T10459Banoxantrone dihydrochloride;巴诺蒽醌盐酸盐Banoxantrone|||Banoxantrone dihydrochloride|||Banoxantrone|||AQ4
Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.
价 格:¥电议型 号:T10459产 地:中国大陆