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T15244Ertugliflozin L-pyroglutamic acid;埃格列净PF-04971729 L-pyroglutamic acid;埃格列净|||PF-04971729 L-pyrogluta
Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-pyroglutamic acid can be used for studies about the treatment of type 2 diabetes mellitus.
价 格:¥电议型 号:T15244产 地:中国大陆
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T15243Ertiprotafib;化合物 T15243PTP 112;PTP 112
Ertiprotafib is a PTP1B, IkB kinase β (IKK-β), and a dual PPARα and PPARβ agonist inhibitor ( IC50s: 1.6 μM for PTP1B, 400 nM for IKK-β, an EC50 of ~1 μM for PPARα/PPARβ).
价 格:¥电议型 号:T15243产 地:中国大陆
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T15208Elisartan;化合物 T15208HN 65021;HN 65021
Elisartan is a non-peptide pro-drug of angiotensin II AT1 receptor antagonist HN-12206. It also shows anti-hypertension activities.
价 格:¥电议型 号:T15208产 地:中国大陆
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T1518Olmesartan Medoxomil;奥美沙坦酯CS 866|||Benicar;奥美沙坦酯|||CS 866|||Benicar
Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.
价 格:¥电议型 号:T1518产 地:中国大陆
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T15132LDimetacrine tartrate;化合物 T15132LLinostil|||Istonil|||Istonyl|||Miroistonil|||MO 709;Linostil|||Iston
Dimetacrine tartrate is a tricyclic antidepressant (TCA) used for the therapy of depression in Europe and formerly in Japan.
价 格:¥电议型 号:T15132L产 地:中国大陆
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T15024Silmitasertib sodium salt;化合物Silmitasertib sodium saltCX-4945 sodium salt;CX-4945 sodium salt
Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).
价 格:¥电议型 号:T15024产 地:中国大陆
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T15000Cort108297;化合物Cort108297Cort108297
Cort108297 is a selective glucocorticoid receptor modulator and a selective GR antagonist with no affinity for other steroid receptors. Cort108297 showed a high affinity for GRs (Ki: 0.45nM).
价 格:¥电议型 号:T15000产 地:中国大陆
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T1499Dutasteride;度他雄胺GG 745|||Avodart|||GI 198745;GG 745|||Avodart|||度他雄胺|||GI 198745
Dutasteride (GI 198745) is a 5-alpha-reductase inhibitor that inhibits both type-1 and type2 isoforms of the enzyme and is used to treat benign prostatic hyperplasia.
价 格:¥电议型 号:T1499产 地:中国大陆
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T14955Chlorthenoxazine;氯西诺嗪Chlorethylbenzmethoxazone;氯西诺嗪|||Chlorethylbenzmethoxazone
Chlorthenoxazine (Chlorethylbenzmethoxazone) has anti-inflammatory activity.
价 格:¥电议型 号:T14955产 地:中国大陆
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T14954Chlorthal-dimethyl;氯酞酸二甲酯Dimethyl tetrachloroterephthalate;Dimethyl tetrachloroterephthalate
Chlorthal-dimethyl (Dimethyl tetrachloroterephthalate) is used for a pesticide intermediate.
价 格:¥电议型 号:T14954产 地:中国大陆
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T14946Ch55;化合物Ch55Ch-55|||CH 55|||3,5-Di-tert-butylchalcone;Ch-55|||CH 55|||3,5-Di-tert-butylchalcone
Ch55 (3,5-Di-tert-butylchalcone) is an effective inducer of the differentiation of HL60 cells (EC50 = 200 nM) and shows high affinity with RAR-α and RAR-β receptors. Ch55 can be used in studies about cancer.
价 格:¥电议型 号:T14946产 地:中国大陆
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T14925Cenisertib;化合物 T14925AS-703569|||R-763;AS-703569|||R-763
Cenisertib is A potent ATP-competitive multi-kinase inhibitor, showing inhibitory effects on the activity of Aurora-kinase-A/B, ABL1, AKT, STAT5, FLT3, as well as kinase inhibitors of FER and its homolog. Cenisertib inhibits the growth of tumor mast cells (MCS) by inhibiting the activity of several different molecular targets. Cenisertib also inhibits tumor growth in pancreatic, breast, colon, ovarian and lung cancer and leukemia in xenograft models.
价 格:¥电议型 号:T14925产 地:中国大陆
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T14895Tanzisertib;化合物TanzisertibCC-930;CC-930
Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, with potential antifibrotic activity.
价 格:¥电议型 号:T14895产 地:中国大陆
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T1484LPerindopril erbumine;培哚普利叔丁胺S9490-3|||Perindopril tert-butylamine salt;培哚普利叔丁胺|||培哚普利叔丁胺盐|||S9490-3|
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, Perindopril erbumine (S9490-3) is converted to its active form perindoprilat, inhibiting ACE and the conversion of angiotensin I to angiotensin II; consequently, angiotensin II-mediated vasoconstriction and angiotensin II-stimulated aldosterone secretion from the adrenal cortex are inhibited a
价 格:¥电议型 号:T1484L产 地:中国大陆
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T1468Lornoxicam;氯诺昔康Ro 13-9297|||Chlortenoxicam|||TS110;Ro 13-9297|||Chlortenoxicam|||TS110|||氯诺昔康
Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.
价 格:¥电议型 号:T1468产 地:中国大陆
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T14665LMotixafortide TFA(664334-36-5,Free);化合物Motixafortide TFATF 14016 TFA|||BKT140 TFA|||BL-8040 TFA|||T1
Motixafortide TFA(664334-36-5,Free) (BKT140 TFA) is an antagonist of CXCR4 with IC50 of ~1 nM. It induces the apoptosis of AML blasts by down-regulating ERK, BCL-2, MCL-1 and cyclin-D1 via altered miR-15a/16-1 expression.
价 格:¥电议型 号:T14665L产 地:中国大陆
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T14665Motixafortide化合物 T14665BL-8040|||BKT140 (4-fluorobenzoyl)|||TF14016
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).
价 格:¥电议型 号:T14665产 地:中国大陆
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T1461Candesartan坎地沙坦CV 11974|||坎地沙坦
Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
价 格:¥电议型 号:T1461产 地:中国大陆
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T14371Barasertib;巴拉塞替AZD1152;巴拉塞替|||AZD1152
AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.
价 格:¥电议型 号:T14371产 地:中国大陆
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T14333Asoxime dichloride;化合物Asoxime dichlorideTert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate|||Asox
Asoxime dichloride (Tert-Butyl2-(2-hydroxyethyl)-1-pyrrolidinecarboxylate) is an antagonist to acetylcholine receptors (AChRs) including the nicotinic receptor, α7 nAChR. Asoxime dichloride (HI-6) can be used as an antigen and improves vaccination efficacy in the nervous system. Asoxime dichloride involves in modulating immunity response.
价 格:¥电议型 号:T14333产 地:中国大陆