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T82032Isoglobotriaose;化合物 IsoglobotriaoseGala-3Galb-4Glc;Gala-3Galb-4Glc
Isoglobotriaose (Gala-3Galb-4Glc), a mammalian tissue glycosphingolipid, is a Globotriaose analogue. The ganglioside derivatives of Isoglobotriaose and Globotriaose differ in their small intestine distribution: isoglobotriaosylceramide localizes exclusively to the non-epithelial residue, whereas globotriaosylceramide is present in both compartments [1] [2].
价 格:¥电议型 号:T82032产 地:中国大陆
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T82031Isoguaiacin;化合物 IsoguaiacinIsoguaiacin
Isoguaiacin, a natural product [1], exhibits (hass) the potential to be (to exist as) an (a) effective pharmacological agent due to its (its) ability to inhibit (the inhibition of) mushroom tyrosinase. This (The) inhibition is (taking place) in a manner that demonstrates greater (a higher) selectivity towards mushroom tyrosinase compared to human tyrosinase, suggesting a reduced (a lower) risk of off-target effects in humans. Additionally, isoguaiacin shows (displays) promising (promising) activ
价 格:¥电议型 号:T82031产 地:中国大陆
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T82030Isohericerin;化合物 IsohericerinIsohericerin
Isohericerin is a natural isoindolinone-derived product.
价 格:¥电议型 号:T82030产 地:中国大陆
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T8203Gentianose;龙胆三糖Gentianose
Gentianose is a carbohydrate reserve derived from perennial yellow gentian storage roots.
价 格:¥电议型 号:T8203产 地:中国大陆
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T81876MAIT-203;化合物 MAIT-203MAIT-203
MAIT-203, a cyclopentyalanin-derived peptidomimetic, effectively disrupts the interaction between adenomatous polyposis coli (APC) and Asef (RhoGEF4), without affecting APC-Sam68 or APC-striatin interactions. It binds to APC-ARM domains with a K i of 0.015 μM and a K d of 0.036 μM, and notably inhibits the migration and invasion of colorectal cancer cells.
价 格:¥电议型 号:T81876产 地:中国大陆
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T81203SARS-CoV-2-IN-68;化合物 SARS-CoV-2-IN-68SARS-CoV-2-IN-68
SARS-CoV-2-IN-68 (compound 6C) is a covalent inhibitor of both SARS-CoV-2 PLpro and Mpro, exhibiting potent antiviral properties by targeting the Zn-finger domain of PLpro [1].
价 格:¥电议型 号:T81203产 地:中国大陆
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T80203Diaminopropionoyl tripeptide-33;化合物 Diaminopropionoyl tripeptide-33Diaminopropionoyl tripeptide-33
Diaminopropionoyl Tripeptide-33 is a bioactive peptide that safeguards skin cells against UVA-induced DNA damage and is utilized as a cosmetic ingredient [1].
价 格:¥电议型 号:T80203产 地:中国大陆
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T79203Anticancer agent 121;化合物 Anticancer agent 121Anticancer agent 121
Anticancer agent 121, a human lactate dehydrogenase A (hLDHA) inhibitor, exhibits potent anticancer activities, suitable for use in anticancer research [1].
价 格:¥电议型 号:T79203产 地:中国大陆
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T78203NSC194598;化合物 NSC194598NSC194598
NSC194598 is a p53 DNA-binding inhibitor, demonstrating an in vitro IC50 of 180 nM and an in vivo range of 2-40 μM. It disrupts the transcriptional activation of the mutated RET gene in human medullary thyroid carcinoma TT cells. The compound is utilized in research investigating acute toxicity in normal tissues due to radiation and chemotherapy [1] [2].
价 格:¥电议型 号:T78203产 地:中国大陆
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T78010L-GO-203 TFA;化合物 L-GO-203 TFAL-GO-203 TFA
L-GO-203 TFA is a potent inhibitor of the MUC1-C oncoprotein, serving as an anticancer peptide that targets intracellular proteins [1].
价 格:¥电议型 号:T78010产 地:中国大陆
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T76203Syringomycin E;化合物 Syringomycin ESyringomycin E
Syringomycin E, an antifungal cyclic lipodepsinonapeptide, inhibits the growth of Saccharomyces cerevisiae by interacting with the plasma membrane. It induces K+ efflux, Ca2+ influx, and alterations in membrane potential, associated with channel formation [1] [2].
价 格:¥电议型 号:T76203产 地:中国大陆
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T7611ODM-203;化合物ODM-203ODM-203
ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity
价 格:¥电议型 号:T7611产 地:中国大陆
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T7526JNJ-17203212;化合物JNJ-17203212JNJ-17203212
JNJ-17203212 is a potent and selective antagonist of TRPV1 (human TRPV1 and rat TRPV1, IC50 of 65 nM and 102 nM).
价 格:¥电议型 号:T7526产 地:中国大陆
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T752032-(P-Cyanophenyl methylidene hydrazino) adenosine;化合物 2-(P-Cyanophenyl methylidene hydrazino) adenos
2-(P-Cyanophenyl methylidene hydrazino) adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include the inhibition of DNA synthesis and the induction of apoptosis, among others [1].
价 格:¥电议型 号:T75203产 地:中国大陆
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T74203Licoagrochalcone C;化合物 Licoagrochalcone CLicoagrochalcone C
Licoagrochalcone C, a flavonoid compound, demonstrates potent inhibitory effects on NF-κB transcription and significantly reduces LPS-induced NO production, showcasing its bioactive properties [1] [2].
价 格:¥电议型 号:T74203产 地:中国大陆
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T72203Reverse transcriptase-IN-3;化合物 Reverse transcriptase-IN-3Reverse transcriptase-IN-3
Reverse transcriptase-IN-3, a pyrimidine-5-carboxamide derivative, functions as an inhibitor of HIV-1, demonstrating potent activity against both wild-type and mutant strains of HIV-1.
价 格:¥电议型 号:T72203产 地:中国大陆
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T72039CLK1-IN-3;CLK1抑制剂3CLK1-IN-3
Clk1-in-3 is a + selective and highly potent sexual Clk1 inhibitor with an IC50 of 5 nM and 300 pairs higher affinity than Dyrk1A. CLK1-IN-3 also showed highly effective inhibition of Clk2 and Clk4, with IC50 values of 42 and 108 nM, respectively. CLK1-IN-3 is effective in inducing autophagy in vitro and can be used for prevention and human treatment of acute liver injury (ALI).
价 格:¥电议型 号:T72039产 地:中国大陆
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T72038YM-58790;化合物YM-58790YM-58790 free base;YM-58790 free base
YM-58790 free base is a potent mAChR antagonist.YM-58790 free base inhibited M1 mAChR, M2 mAChR, and M3 mAChR with Ki values of 28 nM, 260 nM, and 15 nM, respectively.YM-58790 free base inhibits reflex rhythmic bladder contraction in rats by inhibiting bladder pressurization. YM-58790 free base inhibits reflex rhythmic bladder contractions in rats by inhibiting bladder pressurization.
价 格:¥电议型 号:T72038产 地:中国大陆
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T72037Anti-Influenza agent 4;抗流感剂4Anti-Influenza agent 4
Anti-Influenza agent 4 is a potent and selective inhibitor of influenza virus, inhibiting A/Parma and A/Roma strains with EC50s of 62 nM and 150 nM, respectively.
价 格:¥电议型 号:T72037产 地:中国大陆
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T72036HPK1-IN-36;化合物HPK1-IN-36HPK1-IN-36
HPK1-IN-36 (compound 2) is a potent inhibitor of hematopoietic progenitor kinase 1 (HPK1), demonstrating an inhibitory concentration 50 (IC50) of 0.5 nM [1].
价 格:¥电议型 号:T72036产 地:中国大陆