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T75012SIAIS100；化合物 SIAIS100SIAIS100
SIAIS100, a potent BCR-ABL PROTAC degrader, demonstrates a DC50 value of 2.7 nM, highlighting its efficacy. It is primarily utilized in the investigation of chronic myeloid leukemia (CML) [1].
价 格：￥电议型 号：T75012产 地：中国大陆
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T75011STING-IN-5；化合物 STING-IN-5STING-IN-5
STING-IN-5, a potent inhibitor of the Stimulator of Interferon Genes (STING) pathway, significantly suppresses lipopolysaccharide (LPS)-induced nitric oxide (NO) synthesis in macrophages, exhibiting an IC50 of 1.15 μM. This compound dampens the inflammatory response and offers potential for research into anti-inflammatory diseases and sepsis [1].
价 格：￥电议型 号：T75011产 地：中国大陆
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T75010TD1092；化合物 TD1092TD1092
TD1092, a pan-IAP degrader, effectively degrades cIAP1, cIAP2, and XIAP, catalyzing the activation of Caspase 3/7 and fostering apoptosis in cancer cells through IAP degradation. It also obstructs the TNFα-mediated NF-κB pathway, diminishing the phosphorylation of IKK, IkBα, p65, and p38, and operates as a PROTAC. This compound is utilized in cancer research [1].
价 格：￥电议型 号：T75010产 地：中国大陆
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T7501Iso-H7 dihydrochloride1-(5-硫代异喹啉)-3-甲基哌嗪二盐酸盐1-(5-硫代异喹啉)-3-甲基哌嗪二盐酸盐
Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.
价 格：￥电议型 号：T7501产 地：中国大陆
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T75009PPARγ/GR modulator 1；化合物 PPARγ/GR modulator 1PPARγ/GR modulator 1
PPARγ/GR Modulator 1, an orally active dual agonist for the Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) and Glucocorticoid Receptor (GR), exhibits Ki values of 3.3 and 33.6 μM, respectively. This compound is utilized in metabolic disease research, including diabetes [1].
价 格：￥电议型 号：T75009产 地：中国大陆
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T75008Antitubercular agent-36；化合物 Antitubercular agent-36Antitubercular agent-36
Antitubercular agent-36 (compound 53) is an effective inhibitor of Mycobacterium tuberculosis H37Rv, displaying a minimum inhibitory concentration (MIC90) of 1.25 μg/mL and is utilized in tuberculosis research [1].
价 格：￥电议型 号：T75008产 地：中国大陆
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T75007Antitubercular agent-35；化合物 Antitubercular agent-35Antitubercular agent-35
Antitubercular Agent-35 (compound 42l) is an antitubercular agent effective against Mtb H37Rv and M. Marinum, exhibiting MIC 90 values of 1.25 and 2 μg/mL, respectively. It demonstrates resistance to metabolic degradation by human liver microsomes, rendering it a potential candidate for tuberculosis research [1].
价 格：￥电议型 号：T75007产 地：中国大陆
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T75006Antitubercular agent 34；化合物 Antitubercular agent 34Antitubercular agent 34
Antitubercular agent 34 (compound 42g) effectively inhibits Mtb H37Rv growth, exhibiting a MIC 90 value of 1.25 ?g/mL and demonstrates resistance to metabolic degradation by human liver microsomes, proving its potential for tuberculosis research [1].
价 格：￥电议型 号：T75006产 地：中国大陆
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T75005TGFβ1-IN-3；TGFβ1抑制剂3TGFβ1-IN-3
TGFβ1-IN-3 is a diarylhydrazone derivative with inhibitory effects on fibroblast activation and proliferation.TGFβ1-IN-3 is a candidate compound for the treatment of idiopathic pulmonary fibrosis (IPF).
价 格：￥电议型 号：T75005产 地：中国大陆
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T75004TGFβ1-IN-2；TGFβ1抑制剂2TGFβ1-IN-2
TGFβ1-IN-2, a derivative of diarylacylhydrazones, effectively inhibits fibroblast activation and proliferation and holds potential for idiopathic pulmonary fibrosis (IPF) research [1].
价 格：￥电议型 号：T75004产 地：中国大陆
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T75003Antidepressant agent 4；化合物 Antidepressant agent 4Antidepressant agent 4
Antidepressant agent 4, an orally active compound, demonstrates efficacy as an antidepressant with additional anxiolytic, performance-enhancing, and nootropic activities [1].
价 格：￥电议型 号：T75003产 地：中国大陆
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T75002Antidepressant agent 3；化合物 Antidepressant agent 3Antidepressant agent 3
Antidepressant agent 3, an orally active compound, showcases multifaceted pharmacological properties including antidepressant, anxiolytic, performance-enhancing, and nootropic activities [1].
价 格：￥电议型 号：T75002产 地：中国大陆
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T75001Antibacterial agent 128；化合物 Antibacterial agent 128Antibacterial agent 128
Antibacterial Agent 128, a siderophore analog-Ciprofloxacin (Ciprofloxacin) conjugate connected via a cleavable linker, demonstrates effective antibiotic properties. Specifically, it exhibits activity against P. aeruginosa and B. pseudomallei, with Minimum Inhibitory Concentration (MIC) values ranging from 0.25 to 64 μg/mL and 1 to 32 μg/mL, respectively [1].
价 格：￥电议型 号：T75001产 地：中国大陆
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T75000Mal-Pc；化合物 Mal-PcMal-Pc
Mal-Pc, a phthalocyanine-based molecular photosensitizer featuring maleimides, interacts with GSH to diminish its levels and decrease aggregation, enhancing the ROS (Reactive Oxygen Species)-dependent efficacy of photodynamic therapy (PDT) in targeting cancer cells [1].
价 格：￥电议型 号：T75000产 地：中国大陆
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T7500Isoxazole；异恶唑1,2-oxazole；1,2-oxazole|||异恶唑
Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.
价 格：￥电议型 号：T7500产 地：中国大陆
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T74750NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT；化合物 NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPTNH2-bicyclo[1.1.1]pen
Compound I, NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT, is a topoisomerase I inhibitor with the capability for targeted delivery to cells via conjugated antibodies. It exhibits effective ADC activity both in vivo and in vitro [1].
价 格：￥电议型 号：T74750产 地：中国大陆
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T71750Quinolactacin A1；化合物 (+)-Quinolactacin A1Quinolactacin A1
Quinolactacin A1, a powerful acetylcholinesterase (AChE) inhibitor, originates from the solid-state fermentation of Penicillium citrinum 90648. It is utilized in Alzheimer´s disease research.
价 格：￥电议型 号：T71750产 地：中国大陆
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T70750Deltibant；化合物 DeltibantDeltibant
Deltibantis a bradykinin receptor antagonist.
价 格：￥电议型 号：T70750产 地：中国大陆
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T70136CAM 4750；化合物 CAM 4750CAM 4750
CAM 4750 is a nonpeptide tachykinin NK1 receptor antagonist.
价 格：￥电议型 号：T70136产 地：中国大陆
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T69750p-MPPF dihydrochloride；化合物 p-MPPF dihydrochloridep-MPPF dihydrochloride
p-MPPF dihydrochloride is a selective 5-ht1a serotonin receptor antagonist
价 格：￥电议型 号：T69750产 地：中国大陆
