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TN1493Chrysosplenol Dcancer,Apoptosis,inhibit,ERK1/2,Inhibitor,antitrypanosomal,breast,Chrysosplenol D,ant
Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.
价 格:¥电议型 号:TN1493产 地:中国大陆
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T9532MRT-81Smo,Smoothened,human,C3H10T1/2 cells,inhibit,Shh-light2 cells,rodent,BODIPY-cyclopamine,MRT81,
MRT-81 inhibits human and rodent smoothened?Smo?receptors effectively with an IC50?value of 41 nM in the Shh-light2 cells. MRT-81 has potent hedgehog inhibiting activity. MRT-81 also can be used for the research of cancer[1].
价 格:¥电议型 号:T9532产 地:中国大陆
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T9032MGH-CP1MGH CP1,Lats1/2 deletion,Myc,MGHCP1,TEAD auto-palmitoylation,Apoptosis,Epithelial,MGH-CP1,inh
MGH-CP1 is a potent and selective inhibitor TEAD palmitoylation. It exhibits dose-dependent and potent inhibition of TEAD2/4 auto-palmitoylation in vitro with IC50 of 710 nM and 672 nM, respectively.
价 格:¥电议型 号:T9032产 地:中国大陆
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T9229Pim-1/2 kinase inhibitor 12,4 Thiazolidinedione, 5 p methoxybenzylidene ,2,4Thiazolidinedione, 5pmet
Pim-1/2 kinase inhibitor 1 is an orally active pim-1/2 kinase inhibitor. Pim-1/2 kinase inhibitor 1 blocks the ability of Pim kinases to phosphorylate peptides, and inhibits the pim protein kinase directed phosphorylation of 4E-BP1 and p27 Kip1. Pim-1/2 kinase inhibitor 1 can be used in the cancer research, especially prostate cancer [1].
价 格:¥电议型 号:T9229产 地:中国大陆
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T7663LAngiotensin 1/2 (1-9) TFA(34273-12-6(free base))Angiotensin 1/2 (1 9) TFA(34273 12 6(free base)),Ang
Angiotensin 1/2 (1-9)TFA is containing the amino acids 1-9 that are converted from Angiotensin I/II peptide.
价 格:¥电议型 号:T7663L产 地:中国大陆
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TP1474LXW7LXW7,Integrin,Anti-inflammatory,Inhibitor,LXW-7,ERK1/2,VEGFR-2,LXW 7,αvβ3,inhibit
LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (ECs) targeting ligand. LXW7 is a disulfide cyclic octa-peptide (cGRGDdvc) containing unnatural amino acids flanking both sides of the main functional motif.
价 格:¥电议型 号:TP1474产 地:中国大陆
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T9141ERK-IN-3ERK1/2,inhibit,ERK,Inhibitor,ERK IN 3,RAS,Extracellular signal regulated kinases,cancer,ERKI
ERK-IN-3 is a potent and orally active inhibitor of ERK. It inhibits ERK1/2 with low single-digit nM IC50 values. It can be used for the research of cancers driven by RAS mutations.
价 格:¥电议型 号:T9141产 地:中国大陆
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T11226ERK1/2 inhibitor 1ERK-1/2 inhibitor 1,ERK1/2 inhibitor 1
ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.
价 格:¥电议型 号:T11226产 地:中国大陆
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T8472ERK1/2 inhibitor 2ERK-1/2 inhibitor 2,Extracellular signal regulated kinases,Inhibitor,ASTX 029,ERK1
ASTX029 is a selective and orally bioavailable extracellular signal-regulated kinases 1 and 2 (ERK 1/2) inhibitor, with potential antineoplastic activity.
价 格:¥电议型 号:T8472产 地:中国大陆
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T4019CambinolSIRT1/2 Inhibitor IV;NSC 112546
Cambinol is a cell-permeable b-naphthol compound that inhibits the NAD-dependent deacetylase activity of SIRT1/2 (IC50: 56/59 μM, respectively) in a substrate-, but not NAD-, competitive manner. Cambinol inhibits SIRT5 deacetylase activity only at much
价 格:¥电议型 号:T4019产 地:中国大陆
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T3989SMI-16aPIM1/2 Kinase Inhibitor VI
PIM1/2 Kinase Inhibitor VI, a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-1/2 kinases (IC50: 150/20 nM) while exhibiting little or no activity against a panel of 57 other kinases (≤18% inhibition
价 格:¥电议型 号:T3989产 地:中国大陆
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T3346AKT inhibitor VIIIAKTi-1/2
AKT inhibitor VIII is a highly specific Akt1/2 inhibitor (IC50: 58/210 nM). The selectivity for Akt1 is higher about 36-fold than Akt3.
价 格:¥电议型 号:T3346产 地:中国大陆
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T22574LAngiotensin 1/2 (5-7) acetate
Angiotensin 1/2 (5-7) acetate is a peptide with the sequence H2N-Ile-His-Pro-OH. Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It
价 格:¥电议型 号:T22574L产 地:中国大陆
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T21708LAngiotensin 1/2 + A (2 - 8) AcetateAngiotensin 1/2 + A (2 - 8) Acetate (51833-76-2 Free base)
Angiotensin 1/2 + A (2 - 8) Acetate is a Vasoconstrictor.
价 格:¥电议型 号:T21708L产 地:中国大陆
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T11226ERK1/2 inhibitor 1ERK1/2 inhibitor 1
ERK1/2 inhibitor 1 is a potent, orally bioavailable ERK1/2 inhibitor, showing 60% inhibition at 1 nM and an IC50 of 3.0 nM against ERK1 and ERK2, respectively.
价 格:¥电议型 号:T11226产 地:美洲
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T8472ERK1/2 inhibitor 2;化合物ASTX029ASTX-029|||ASTX029;ASTX-029|||ASTX029
ERK1/2 inhibitor 2 (ASTX029) is a selective and orally bioavailable extracellular signal-regulated kinases 1 and 2 (ERK 1/2) inhibitor, with potential antineoplastic activity.
价 格:¥电议型 号:T8472产 地:中国大陆
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T80282cPcAMP1/26;化合物 cPcAMP1/26cPcAMP1/26
cPcAMP1/26, an antimicrobial peptide, exhibits potent bactericidal activity against A. hydrophila and S. aureus by inducing depolarization of the bacterial plasma membrane and elevating intracellular ROS (Reactive Oxygen Species) levels [1].
价 格:¥电议型 号:T80282产 地:中国大陆
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T79811DDR1/2 inhibitor-2;化合物 DDR1/2 inhibitor-2DDR1/2 inhibitor-2
DDR1/2 Inhibitor-2 (Example 31) serves as an inhibitor of DDR1/DDR2, exhibiting IC50 values below 100 nM. It is applicable in cancer and fibrotic disease research [1].
价 格:¥电议型 号:T79811产 地:中国大陆
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T79594COX-1/2-IN-5;化合物 COX-1/2-IN-5COX-1/2-IN-5
COX-1/2-IN-5 (compound 2a) functions as a dual inhibitor of COX1/2, demonstrating inhibitory concentrations (IC50) of 2.650 μM and 0.958 μM, respectively, and exhibits anticancer activity by inhibiting liver cancer HepG2 cells with an IC50 of 60.75 μM [1].
价 格:¥电议型 号:T79594产 地:中国大陆
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T79592COX-1/2-IN-4;化合物 COX-1/2-IN-4COX-1/2-IN-4
COX-1/2-IN-4 (compound 2b) is a dual COX-1 and COX-2 inhibitor with respective IC50 values of 0.239 μM for COX-1 and 0.191 μM for COX-2. Additionally, it demonstrates moderate anticancer activity, exhibiting IC50 values of 30.79 μM against COLO205 cancer cell lines and 74.15 μM against B16F1 cancer cell lines [1].
价 格:¥电议型 号:T79592产 地:中国大陆