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产品数：86101
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T6908NSC 228155Epidermal growth factor receptor,Histone Acetyltransferase,EGFR,HER1,HATs,inhibit,Inhibito
NSC228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
价 格：￥电议型 号：T6908产 地：中国大陆
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T7123AMG-47aInhibitor,signal,kinases,AMG 47a,JAK,Janus kinase,AMG-47a,transduction,Src,VEGFR,cytoplamic,p
AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells.
价 格：￥电议型 号：T7123产 地：中国大陆
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T6733WZ-3146EGFR,HER1,WZ-3146,Epidermal growth factor receptor,WZ 3146,ErbB-1,WZ3146,inhibit,Inhibitor
WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).
价 格：￥电议型 号：T6733产 地：中国大陆
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T2518ARRY-380 (analog )Inhibitor,HER1,EGFR,ARRY380 (analog ),Epidermal growth factor receptor,ARRY 380 (a
ARRY-380 is a potent and selective HER2 inhibitor.
价 格：￥电议型 号：T2518产 地：中国大陆
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T11163EGFR-IN-9EGFRIN9,EGFR IN 9
EGFR-IN-9 is a potent EGFR kinase inhibitor with IC50s of 7 nM, 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). EGFR-IN-9 has antitumor activity.
价 格：￥电议型 号：T11163产 地：中国大陆
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TQ0092NaquotinibEpidermal growth factor receptor,EGFR,ASP 8273,HER1,ErbB-1,ASP-8273,inhibit,Naquotinib,Inh
Naquotinib (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR.
价 格：￥电议型 号：TQ0092产 地：中国大陆
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T8976PD-089828EGFR,ATP,nonselective,PD 089828,PDGFR,autophosphorylation,PD089828,HER1,Epidermal growth fa
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 μM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 = 0.18 μM)
价 格：￥电议型 号：T8976产 地：中国大陆
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T9072TuxobertinibTuxobertinib,inhibit,ErbB-1,EGFR,BDTX 189,BDTX189,mutants,Epidermal growth factor recept
BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations(KDs of 0.2, 0.76, 13 and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively). BDTX-189 exhibits anticancer activity.
价 格：￥电议型 号：T9072产 地：中国大陆
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T8742G5-7antiangiogenic,inhibit,Apoptosis,JAK,Glioma,G-5-7,cycle,G5 7,phase,G57,STAT3,cell,Inhibitor,EGFR
JAK2 inhibitor G5-7 is an orally active JAK2 inhibitor, selectively inhibits JAK2–mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 has the potential for glioma study
价 格：￥电议型 号：T8742产 地：中国大陆
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T7101Tyrphostin AG30HER1,ErbB-1,Inhibitor,EGFR,Tyrphostin AG30,Epidermal growth factor receptor,Tyrphosti
Tyrphostin AG30 (AG30) is a potent protein tyrosine kinases (PTK) inhibitor.
价 格：￥电议型 号：T7101产 地：中国大陆
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T6479Dovitinib lactate hydrateVEGFR1,FGFR1,TKI258 lactate,SCFR,CD117,Dovitinib lactate hydrate,FGFR,Fms l
Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM, also potent to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs with IC50 of 8-13 nM, less potent to InsR, EGFR, c-Met, EphA2, Tie2, IGFR1 and HER2. Phase 4.
价 格：￥电议型 号：T6479产 地：中国大陆
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TQ0255OlafertinibInhibitor,ErbB-1,Olafertinib,Epidermal growth factor receptor,NSCLC,HER1,EGFR,inhibit
CK-101 (RX-518) is a novel mutant-selective, irreversible, orally available EGFR inhibitor. It can overcome T790M-mediated resistance in NSCLC.
价 格：￥电议型 号：TQ0255产 地：中国大陆
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T6153IcotinibIcotinib,Inhibitor,BPI2009,BPI 2009,ErbB-1,HER1,inhibit,EGFR,Epidermal growth factor recepto
Icotinib is an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity.
价 格：￥电议型 号：T6153产 地：中国大陆
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T9912TrastuzumabEGFR,Trastuzumab,Anti-Human HER2, Humanized Antibody,Epidermal growth factor receptor,HER
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer.
价 格：￥电议型 号：T9912产 地：中国大陆
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T4485LazertinibErbB-1,YH 25448,GNS1480,Lazertinib,EGFR,Inhibitor,YH-25448,Epidermal growth factor recepto
Lazertinib is an effective, highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1.7 nM, 2 nM, 5 nM, 20.6 nM and 76 nM for Del19/T790M, L858R/T790M, Del19, L85R and Wild type EGFR respectively.
价 格：￥电议型 号：T4485产 地：中国大陆
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T6427ButeinPDE4,Epidermal growth factor receptor,Inhibitor,EGFR,MAPK,ErbB-1,Apoptosis,Autophagy,FoxO3a,in
Butein, a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.
价 格：￥电议型 号：T6427产 地：中国大陆
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T9052XL092Axl,c-Met/HGFR,Vascular endothelial growth factor receptor,p-MET,XL092,TAM Receptor,p-VEGFR2,Me
JUN04542 is an Axl Mer cMet KDR inhibitor for the treatment of Axl and Mer receptor tyrosine kinase- dependent disorders.
价 格：￥电议型 号：T9052产 地：中国大陆
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T10802CHMFL-EGFR-202CHMFLEGFR202,CHMFL EGFR 202
CHMFL-EGFR-202 is a potent, irreversible inhibitor of EGFR mutant kinase (IC50s: 5.3 nM and 8.3 nM for drug-resistant mutant EGFR T790M and WT EGFR kinases).
价 格：￥电议型 号：T10802产 地：中国大陆
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T6932PD168393Autophagy,EGFR,ErbB-1,HER1,PD 168393,PD168393,Apoptosis,PDGFR,Epidermal growth factor recept
PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.
价 格：￥电议型 号：T6932产 地：中国大陆
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T11158EGFR-IN-11EGFRIN11,EGFR IN 11
EGFR-IN-11 is a selective inhibitor of EGFR-tyrosine kinase and induces cell apoptosis. EGFR-IN-11 inhibits triple mutant EGFRL858R/T790M/C797S with an IC50 of 18 nM and arrests cell cycle at G0/G1.
价 格：￥电议型 号：T11158产 地：中国大陆
