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  • T6286RGFP966 (E-isomer)RGFP-966,RGFP966

    RGFP966 is an HDAC3 inhibitor with IC50 of 0.08 μM, exhibits > 200-fold selectivity over other HDAC.

    价 格：￥电议型 号：T6286产 地：中国大陆

  • T62360AChE-IN-26

    AChE-IN-26 is an AChE (acetylcholinesterase) inhibitor (IC50= 0.42 μM). AChE-IN-26 has research value in Alzheimer’s disease.

    价 格：￥电议型 号：T62360产 地：中国大陆

  • T62083Camonsertib

    Camonsertib is an orally active, selective ATR kinase inhibitor (IC50= 1.00 nM). Camonsertib exhibits 30-fold selectivity for ATR over mTOR (IC50=120 nM) and >2,000-fold selectivity over ATM, PI3Kα kinases, and DNA-PK. Camonsertib exhibits potent antitumor activity.

    价 格：￥电议型 号：T62083产 地：中国大陆

  • T62420P2Y2R/GPR17 antagonist 1

    P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R and GPR17 antagonist. P2Y2R/GPR17 antagonist 1 shows IC50 values of 3.17 ?M and 1.67 ?M against P2Y2R and GPR17, respectively. P2Y2R/GPR17 antagonist 1 shows excellent metabolic stability in human liver microsomes.

    价 格：￥电议型 号：T62420产 地：中国大陆

  • T62042BDZ-g

    BDZ-g is a potent and selective antagonist of AMPA receptor. BDZ-g can be used for the research of various neurological disorders involving excessive activity of AMPA receptors.

    价 格：￥电议型 号：T62042产 地：中国大陆

  • TQ0270Atrasentan hydrochlorideA 147627,A-147627,(+)-A 127722,Atrasentan hydrochloride,Atrasentan,ABT627,AB

    Atrasentan hydrochloride is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).

    价 格：￥电议型 号：TQ0270产 地：中国大陆

  • T62285Enbezotinib

    Enbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer.

    价 格：￥电议型 号：T62285产 地：中国大陆

  • T62769Tribendimidine

    Tribendimidine is an orally active and broad-spectrum anthelmintic agent. Tribendimidine exhibits particularly high activity against A. lumbricoides and N. americanus. Tribendimidine is also an agonist of L-type nicotinic acetylcholine receptor (nAChR).

    价 格：￥电议型 号：T62769产 地：中国大陆

  • T6246CobicistatInhibitor,HIV,Human immunodeficiency virus,antiviral,HIV-1,Cytochrome P450,CYPs,CYP3A,Cobi

    Cobicistat is a carbamate and thiazole derivative that functions as a CYTOCHROME P450 CYP3A INHIBITOR to enhance the concentration of ANTI-HIV AGENTS, with which it is used in combination, for the treatment of HIV INFECTIONS.

    价 格：￥电议型 号：T6246产 地：中国大陆

  • T62209HS-276

    HS-276 is an orally active, potent and highly selective TAK1 inhibitor (Ki= 2.5 nM). HS-276 exhibits significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 exhibits research potential for rheumatoid arthritis (RA) research.

    价 格：￥电议型 号：T62209产 地：中国大陆

  • T62228KRAS G12D inhibitor 14

    KRAS G12D inhibitor 14 is an effective inhibitor of KRAS G12D, showing significant antitumor effect and tumor growth inhibition in CT26 tumor models.

    价 格：￥电议型 号：T62228产 地：中国大陆

  • T62929RLX-33

    RLX-33 is a potent, selective and blood-brain barrier (BBB) penetrant antagonist of relaxin family peptide 3 (RXFP3, IC50=2.36 μM). RLX-33 also blocks relaxin-3-induced ERK1/2 phosphorylation, with IC50s of 7.82 and 13.86 μM for ERK1 and ERK2 phosphorylation, respectively. RLX-33 can inhibits the stimulation of food intake induced by the RXFP3-selective agonist R3/I5 in rats.

    价 格：￥电议型 号：T62929产 地：中国大陆

  • T62269F 14679

    F 14679 is a prototypical 5-HT 1A agonist with a pK i of 10.23. F 14679 induces large Ca 2+ responses [1].

    价 格：￥电议型 号：T62269产 地：中国大陆

  • TQ0259AtrasentanAtrasentan,Endothelin Receptor,A 147627,ABT627,Inhibitor,inhibit,A147627,ABT 627

    Atrasentan (ABT-627) is an endothelin receptor antagonist (IC50: 0.0551 nM for ETA).

    价 格：￥电议型 号：TQ0259产 地：中国大陆

  • T62204NR2F6 modulator-1

    NR2F6 modulator-1 is a potent modulator of nuclear receptor subfamily 2, group F, member 6 (NR2F6). NR2F6 modulator-1 can be used for researching immune modulation and modulation of cancer stem cell activity.

    价 格：￥电议型 号：T62204产 地：中国大陆

  • T62404SHMT-IN-2

    SHMT-IN-2 is a stereo specific inhibitor of human SHMT1/2 with IC50 values of 13 nM and 66 nM for SHMT1 and SHMT2, respectively. SHMT-IN-2 can block the growth of many human cancer cells, and has sensitivity for B-cell lymphomas.

    价 格：￥电议型 号：T62404产 地：中国大陆

  • T62530N-Arachidonyldopamine

    N-Arachidonyldopamine is a potent and selective endogenous CB1 receptor agonist (Ki= 250 nM). N-Arachidonyldopamine is also a potent and selective TRPV1 agonist (EC50= ~ 50 nM).

    价 格：￥电议型 号：T62530产 地：中国大陆

  • T6299GDC-0152GDC0152；GDC 0152

    GDC-0152 is a potent inhibitor of IAPs.

    价 格：￥电议型 号：T6299产 地：中国大陆

  • T6297Alvespimycin hydrochlorideAlvespimycin (17-DMAG) HCl；NSC 707545；17-DMAG hydrochloride；KOS-1022；BMS 8

    17-DMAG is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.

    价 格：￥电议型 号：T6297产 地：中国大陆

  • T6296RAF265CHIR-265

    RAF265 (CHIR-265) is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 nM, and exhibits potent inhibition on VEGFR2 phosphorylation with EC50 of 30 nM. Phase 2.

    价 格：￥电议型 号：T6296产 地：中国大陆

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