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T71308DSP-6952；化合物 DSP-6952DSP-6952
DSP-6952 is a 5-HT4 receptor partial agonist, inhibiting visceral hypersensitivity and ameliorating gastrointestinal dysfunction.
价 格：￥电议型 号：T71308产 地：中国大陆
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T71307JNJ-40413269；化合物 JNJ-40413269JNJ-40413269
JNJ-40413269 is a competitive inhibitor of fatty acid amide hydrolase (FAAH), which demonstrates robust central target engagement, and shows efficacious in a rat model of neuropathic pain.
价 格：￥电议型 号：T71307产 地：中国大陆
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T71306Gemfibrozil-d6；化合物 Gemfibrozil-d6Gemfibrozil-d6
Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif l
价 格：￥电议型 号：T71306产 地：中国大陆
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T71305Clofibric Acid-d4；化合物 Clofibric Acid-d4Clofibric Acid-d4
Clofibric acid-d4 is intended for use as an internal standard for the quantification of clofibric acid by GC- or LC-MS. Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 ?M in a transactivation assay) and the active metabolite of clofibrate. It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxal
价 格：￥电议型 号：T71305产 地：中国大陆
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T71304AH057；化合物 AH057AH057
AH057 is a novel JAK inhibitor, effectively blocking the JAK/STAT pathways by directly inhibiting JAK1/2 kinase activities, and leading to compromised cell proliferation and invasion, increasing apoptosis, arrested cell cycles, and impairing tumor progression in vitro and in vivo
价 格：￥电议型 号：T71304产 地：中国大陆
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T71303Flufenamic Acid-d4；化合物 Flufenamic Acid-d4Flufenamic Acid-d4
Flufenamic acid-d4 is intended for use as an internal standard for the quantification of flufenamic acid by GC- or LC-MS. Flufenamic acid is a non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor (IC50s = 3 and 9.3 ?M for human COX-1 and COX-2, respectively). Flufenamic acid inhibits TNF-α-induced increases in COX-2 levels and NF-κB activation in HT-29 colon cancer cells in a concentration-dependent manner. It inhibits calcium influx induced by fMLP or A23187 in human polymorphonuclear
价 格：￥电议型 号：T71303产 地：中国大陆
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T71302Norfluoxetine-d5 HCl；化合物 Norfluoxetine-d5 HClNorfluoxetine-d5 HCl
Norfluoxetine-d5 is intended for use as an internal standard for the quantification of norfluoxetine by GC- or LC-MS. Norfluoxetine is an active metabolite of the antidepressant fluoxetine. It is formed from fluoxetine by the cytochrome P450 (CYP) isoforms CYP2C9, CYP2C19, and CYP3A. Norfluoxetine inhibits serotonin (5-HT) uptake in rat brain synaptosomal membrane preparations (Ki = 44.7 nM) and isolated human platelets (IC50 = ~15 nM). It has been found in the tissues of fish exposed to wastewa
价 格：￥电议型 号：T71302产 地：中国大陆
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T71301Opaganib HCl；化合物 Opaganib HClOpaganib HCl
ABC294640, also known as Opaganib, is an orally available, aryladamantane compound and selective inhibitor of sphingosine kinase-2 (SK2) with potential antineoplastic activity. Upon administration, ABC294640 competitively binds to and inhibits SK2, thereby preventing the phosphorylation of the pro-apoptotic amino alcohol sphingosine to sphingosine 1-phosphate (S1P), the lipid mediator that is pro-survival and critical for immunomodulation. This may eventually lead to the induction of apoptosis a
价 格：￥电议型 号：T71301产 地：中国大陆
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T71300Pentoxifylline-d6；化合物 Pentoxifylline-d6Pentoxifylline-d6
Pentoxifylline-d6 is intended for use as an internal standard for the quantification of pentoxifylline by GC- or LC-MS. Pentoxifylline is a hemorrheologic agent. It increases the deformability of washed isolated human erythrocytes when used at a concentration of 100 ?M. Pentoxifylline (1, 2, and 3 mM) inhibits ADP-induced platelet aggregation in isolated human whole blood. It inhibits thrombus formation induced by ADP in a hamster cheek pouch model when administered at doses of 5, 10, and 20 mg/
价 格：￥电议型 号：T71300产 地：中国大陆
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T7130Navarixin；化合物NavarixinMK-7123|||SCH 527123；MK-7123|||SCH 527123
Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in animal models, characteristics that may be beneficial in the treatment of conditions with unbalanced pulmonary neutrophilia.
价 格：￥电议型 号：T7130产 地：中国大陆
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T70713BW-10；化合物 BW-10BW-10
BW-10 potently inhibits bombesin evoked release of gastrointestinal hormones in vitro and in vivo.
价 格：￥电议型 号：T70713产 地：中国大陆
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T69713Fosamprenavir sodium；化合物 Fosamprenavir sodiumFosamprenavir sodium
Fosamprenavir sodium is an HIV protease inhibitor that is the water soluble prodrug of amprenavir.
价 格：￥电议型 号：T69713产 地：中国大陆
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T6918Olmutinib；奥莫替尼HM61713, BI 1482694|||BI 1482694|||HM61713；HM61713, BI 1482694|||奥莫替尼|||BI 1482694|||H
Olmutinib (HM61713, BI 1482694) is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutant forms of EGFR, thereby leading to cell death of EGFR-expressing tumor cells. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced as compared to non-selective EGFR inhibitors which also inhibit the EGFR wild-type form.
价 格：￥电议型 号：T6918产 地：中国大陆
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T68713RX-RA 69；化合物 RX-RA 69RX-RA 69
RX-RA 69 is a pyrimido-pyrimidine derivative and PDA-inhibitor which inhibits tumor cell induced platelet aggregation in vitro.
价 格：￥电议型 号：T68713产 地：中国大陆
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T67713Questiomycin A derivatives 14；寻霉素A衍生物14Questiomycin A derivatives 14
Questiomycin A derivatives 14 is a Questiomycin A derivative.
价 格：￥电议型 号：T67713产 地：中国大陆
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T671393-(Trifluoromethyl)benzamide；化合物 3-(Trifluoromethyl)benzamide3-(Trifluoromethyl)benzamide
3-(Trifluoromethyl)benzamide is a useful organic compound for research related to life sciences. The catalog number is T67139 and the CAS number is 1801-10-1.
价 格：￥电议型 号：T67139产 地：中国大陆
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T671384-(Difluoromethoxy)-3-hydroxybenzaldehyde；化合物 4-(Difluoromethoxy)-3-hydroxybenzaldehyde4-(Difluorome
4-(Difluoromethoxy)-3-hydroxybenzaldehyde is a useful organic compound for research related to life sciences. The catalog number is T67138 and the CAS number is 151103-08-1.
价 格：￥电议型 号：T67138产 地：中国大陆
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T671371-Methyl-1,2,4-triazole；化合物 1-Methyl-1,2,4-triazole1-Methyl-1,2,4-triazole
1-Methyl-1,2,4-triazole is a useful organic compound for research related to life sciences. The catalog number is T67137 and the CAS number is 6086-21-1.
价 格：￥电议型 号：T67137产 地：中国大陆
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T671361-Hydroxy-2-butanone；1-羟基-2-丁酮1-Hydroxy-2-butanone
1-Hydroxy-2-butanone is a natural product that can be extracted from bamboo juice and tomato leaves and has anti-tuberculosis activity.
价 格：￥电议型 号：T67136产 地：中国大陆
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T671357-Azaindole-3-carboxylic acid；化合物 7-Azaindole-3-carboxylic acid7-Azaindole-3-carboxylic acid
7-Azaindole-3-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T67135 and the CAS number is 156270-06-3.
价 格：￥电议型 号：T67135产 地：中国大陆
