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T71345Cgs 21197；化合物 Cgs 21197Cgs 21197
Cgs 21197 is an adenosine A2 receptor antagonist.
价 格：￥电议型 号：T71345产 地：中国大陆
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T71344G-479；化合物 G-479G-479
G-479 is an potent MEK inhibitor. Structurally, G-479 is an analogue of GDC-0623 (or so-call Me-Too drug). G-479 with polarity distributed throughout the molecule was shown improved bioactivity over GDC-0623 in many aspects.
价 格：￥电议型 号：T71344产 地：中国大陆
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T71343GSK1997132B；化合物 GSK1997132BGSK1997132B
GSK1997132B is a potent, metabolically stable and centrally penetrant PPARγ partial agonist.
价 格：￥电议型 号：T71343产 地：中国大陆
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T71342Isamoltan；化合物 IsamoltanIsamoltan
Isamoltan is a 5-HT(1B) receptor antagonist.
价 格：￥电议型 号：T71342产 地：中国大陆
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T71341Myclobutanil hydroxide；化合物 Myclobutanil hydroxideMyclobutanil hydroxide
Myclobutanil hydroxide is a 14-α demethylase inhibitor that inhibits ergosterol synthesis and fungal cell wall formation. It also weakly inhibits testosterone production.
价 格：￥电议型 号：T71341产 地：中国大陆
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T7134Mavacamten；化合物MYK-461MYK-461|||SAR439152；MYK-461|||SAR439152
Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)
价 格：￥电议型 号：T7134产 地：中国大陆
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T71339XL413 HCl；XL413 盐酸盐XL413 hydrochloride|||BMS-863233 HCl；XL413 hydrochloride|||BMS-863233 HCl
XL413 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.XL413 HCl inhibited CK2 and PIM1 with IC50 values of 215 and 42 nM, respectively.XL413 HCl showed an EC50 value of 118 against pMCM.
价 格：￥电议型 号：T71339产 地：中国大陆
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T71338Patidegib HCl；化合物 Patidegib HClPatidegib HCl
Patidegip, laos known as Saridegib and IPI-926, is an orally bioavailable, cyclopamine-derived (for structure comparison see Fig 1) inhibitor of the Hedgehog (Hh) pathway with potential antineoplastic activity. Specifically, Hedgehog pathway inhibitor IPI-926 binds to and inhibits the cell membrane-spanning G-protein coupled receptor SMO, which may result in the suppression of Hh pathway signaling and a decrease in tumor cell proliferation and survival. SMO is activated upon binding of Hh ligan
价 格：￥电议型 号：T71338产 地：中国大陆
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T71337AJ-108235；化合物 AJ-108235AJ-108235
AJ-108235 is a novel inhibitor of long chain fatty acid elongase 6 (ELOVL6).
价 格：￥电议型 号：T71337产 地：中国大陆
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T71336CASP3 Activator 1541B；化合物 CASP3 Activator 1541BCASP3 Activator 1541B
CASP3 Activator 1541B is an activator of the proenzyme forms of caspase-3, and is an inducer of cell death.
价 格：￥电议型 号：T71336产 地：中国大陆
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T71335PF-3774076；化合物 PF-3774076PF-3774076
PF-3774076 is a CNS penetrant, potent, selective, partial agonist at the human α1A adrenoceptor. PF-3774076 is selective over α1B and α1D adrenoceptors.
价 格：￥电议型 号：T71335产 地：中国大陆
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T71333Iganidipine HCl；化合物 Iganidipine HClIganidipine HCl
NKY-722 (HCl), also known as Iganidipine, is a calcium channel blocker potentially for thetreatment of glaucoma.
价 格：￥电议型 号：T71333产 地：中国大陆
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T71332NRC-2694 hydrochloride；化合物 NRC-2694 hydrochlorideNRC-2694 hydrochloride
NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.
价 格：￥电议型 号：T71332产 地：中国大陆
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T71331NRC-2694 dihydrochloride；化合物 NRC-2694 dihydrochlorideNRC-2694 dihydrochloride
NRC-2694 dihydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.
价 格：￥电议型 号：T71331产 地：中国大陆
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T71330Bexin-1；化合物 Bexin-1Bexin-1
Bexin-1 is an inhibitor of Munc13-4 membrane binding which targets the Munc13-4 C2 domain-membrane interface, and inhibits ionomycin-stimulated ANF-EGFP secretion.
价 格：￥电议型 号：T71330产 地：中国大陆
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T7133Anagliptin；阿拉格列汀SK-0403；SK-0403|||阿拉格列汀
Anagliptin (SK-0403) is a potent Inhibitor of DPP-4(IC50 of 3.8 nM), for the treatment of type 2 diabetes mellitus.
价 格：￥电议型 号：T7133产 地：中国大陆
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T71329Theophylline-d6；化合物 Theophylline-d6Theophylline-d6
Theophylline-d6 is intended for use as an internal standard for the quantification of theophylline by GC- or LC-MS. Theophylline is an inhibitor of phosphodiesterase. It is also an adenosine A1 and A2 receptor antagonist. Theophylline induces relaxation of isolated cat bronchial smooth muscle segments precontracted with acetylcholine. It inhibits ovalbumin-induced increases in bronchoalveolar lavage fluid (BALF) eosinophil infiltration in an ovalbumin-sensitized mouse model of allergic asthma. F
价 格：￥电议型 号：T71329产 地：中国大陆
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T71328Theobromine-d6；化合物 Theobromine-d6Theobromine-d6
Theobromine-d6 is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities. It is an adenosine A1 receptor antagonist. Theobromine increases AMPK phosphorylation and inhibits adipocyte differentiation, ERK and JNK phosphorylation, and IL-6 and TNF-α production in 3T3-L1 preadipocytes cultured in differentiation medium.
价 格：￥电议型 号：T71328产 地：中国大陆
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T71327Paraxanthine-d6；化合物 Paraxanthine-d6Paraxanthine-d6
Paraxanthine-d6 is intended for use as an internal standard for the quantification of paraxanthine by GC- or LC-MS. Paraxanthine is an active metabolite of caffeine. It is formed via N3-demethylation of caffeine by the cytochrome P450 (CYP) isoform CYP1A2. Paraxanthine is an adenosine A1 and A2 receptor antagonist. In vivo, paraxanthine increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity, as well as inhibits motor depression induced by the adenosine A1 agoni
价 格：￥电议型 号：T71327产 地：中国大陆
