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  • T80713α-Glucosidase-IN-37;化合物 α-Glucosidase-IN-37α-Glucosidase-IN-37

    α-Glucosidase-IN-37 (Compound 11) moderately inhibits lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophages, exhibiting an inhibitory concentration 50 (IC50) value of 23.7 μM. Additionally, this compound demonstrates weak inhibitory activity against α-Glucosidase [1].

    价 格:¥电议型 号:T80713产 地:中国大陆

  • T79713JMJD3/HDAC-IN-1;化合物 JMJD3/HDAC-IN-1JMJD3/HDAC-IN-1

    Compound A5b, also known as JMJD3/HDAC-IN-1, is a dual inhibitor that targets both JMJD3 (Jumonji domain-containing protein demethylase 3) and HADC1 (histone deacetylase, IC50 = 16 nM). It induces hypermethylation of histone H3K27 and hyperacetylation of H3K9, while also promoting apoptosis through the cleavage of caspase-7 and PARP. This compound has demonstrated the ability to effectively inhibit cancer cell cloning, migration, and invasion [1].

    价 格:¥电议型 号:T79713产 地:中国大陆

  • T78713SARS-CoV-2-IN-40;化合物 SARS-CoV-2-IN-40SARS-CoV-2-IN-40

    SARS-CoV-2-IN-40 (Compound 19), a SARS-CoV-2 inhibitor, effectively suppresses the infection of Calu3 lung cells by the BA.1 and BA.5 variants, exhibiting half-maximal inhibitory concentrations (IC50s) of 100 nM and 160 nM, respectively [1].

    价 格:¥电议型 号:T78713产 地:中国大陆

  • T77713BTM-3566;化合物BTM-3566BTM 3566|||BTM3566;BTM 3566|||BTM3566

    BTM-3566 activates the ISR through the mitochondrial protease OMA1.BTM-3566 induces apoptosis in cancer cells. BTM-3566 overactivates the mitochondrial ISR to study DLBCL.

    价 格:¥电议型 号:T77713产 地:中国大陆

  • T77139Pavurutamab;化合物 PavurutamabPavurutamab

    Pavurutamab (AMG-701) is a bispecific T-cell engager that targets CD3 and B-cell maturation antigens (BCMA), based on the extended half-life derived from Pacanalotamab. Its Fc region is engineered for improved pharmacokinetics, offering potential in immune regulation and the treatment of multiple myeloma (MM) [1] [2] [3] [4].

    价 格:¥电议型 号:T77139产 地:中国大陆

  • T77138Ragifilimab;拉格芙利单抗INCAGN-01876|||INCAGN-1876|||CM-701;INCAGN-01876|||INCAGN-1876|||CM-701

    Ragifilimab (INCAGN-1876) is an agonist monoclonal antibody targeting glucocorticoid-induced TNFR-associated protein (GITR). Ragifilimab can be used in the study of advanced or metastatic solid tumors.

    价 格:¥电议型 号:T77138产 地:中国大陆

  • T77137Rafivirumab;化合物 RafivirumabRafivirumab

    Rafivirumab (CR57) is a monoclonal antibody designed for rabies prophylaxis, exhibiting neutralizing efficacy against a wide range of rabies virus (RABV) variants. It is also utilized in cocktail research studies [1] [2] [3].

    价 格:¥电议型 号:T77137产 地:中国大陆

  • T77136Quisovalimab;化合物 QuisovalimabQuisovalimab

    Quisovalimab (AVTX-002; AEVI 002; SAR 252067), a human monoclonal antibody targeting LIGHT, a tumor necrosis factor (TNF)-related cytokine (TNFSF14), is crucial for managing acute respiratory distress syndrome (ARDS) and cytokine release syndrome (CRS) in COVID-19. This compound has potential applications in treating ARDS related to COVID-19 and is subject to ongoing research [1].

    价 格:¥电议型 号:T77136产 地:中国大陆

  • T77135Tafasitamab;塔法西他单抗MOR00208|||XmAb5574|||Tafasitamab-cxix;MOR00208|||XmAb5574|||Tafasitamab-cxix

    Tafasitamab (XmAb5574) is an FC-modified humanized monoclonal antibody targeting the human B-cell surface antigen CD19 for the study of diffuse large B-cell lymphoma.

    价 格:¥电议型 号:T77135产 地:中国大陆

  • T77134Pulocimab;化合物 PulocimabPulocimab

    Pulocimab, an anti-VEGFR2 monoclonal antibody (mAb), is utilized in cancer research [1].

    价 格:¥电议型 号:T77134产 地:中国大陆

  • T77133Prolgolimab;化合物 ProlgolimabProlgolimab

    Prolgolimab (BCD-100), a human IgG1 anti-PD-1 monoclonal antibody featuring the Fc-silencing ´LALA´ mutation, is utilized in advanced melanoma research [1].

    价 格:¥电议型 号:T77133产 地:中国大陆

  • T77132Clesrovimab;单抗ClesrovimabMK-1654;MK-1654

    Clesrovimab (MK1654) is an anti-respiratory syncytial virus protein F human monoclonal antibody for the prevention and treatment of respiratory syncytial virus infections.

    价 格:¥电议型 号:T77132产 地:中国大陆

  • T77131Clervonafusp alfa;化合物 Clervonafusp alfaClervonafusp alfa

    Clervonafusp alfa (VAL-1221) is a fusion protein designed to target both cytosolic and lysosomal glycogen, thereby addressing the underlying mechanisms of Pompe disease. This compound integrates the Fab segment of a cell-penetrating antibody with recombinant human acid alpha-glucosidase (rhGAA). The antibody´s Fab portion exploits the nucleoside transporter ENT-2 for cytosolic entry, while the rhGAA component accesses lysosomes through mannose-6-phosphate receptors (M6PRs). This dual-targe

    价 格:¥电议型 号:T77131产 地:中国大陆

  • T77130Pasotuxizumab;化合物 PasotuxizumabPasotuxizumab

    Pasotuxizumab (BAY 2010112) is a bispecific T-cell engager (BiTE) targeting PSMA and CD3 with dissociation constants (K D) of 47.0 nM and 9.4 nM for PSMA and CD3, respectively. It is utilized in the study of metastatic castration-resistant prostate cancer (mCRPC) [1] [2].

    价 格:¥电议型 号:T77130产 地:中国大陆

  • T7713Benzyl nicotinate;烟酸苄酯Rubriment|||Pycaril;烟酸苄酯|||Rubriment|||Pycaril

    Benzyl nicotinate (Pycaril) is a agonist of GPR109A receptor and GPR109B receptor

    价 格:¥电议型 号:T7713产 地:中国大陆

  • T76713Inebilizumab;伊奈利珠单抗MEDI 551|||MT-0551|||16C4-aFuc|||VIB-0551;MEDI 551|||MT-0551|||16C4-aFuc|||VIB-05

    Inebilizumab is a humanized anti-CD19 monoclonal antibody with enhanced antibody-dependent cell-mediated cytotoxicity against B cells. Inebilizumab can be used to treat a range of autoimmune diseases associated with CD19 B cells, such as multiple sclerosis and optic neuromyelitis.

    价 格:¥电议型 号:T76713产 地:中国大陆

  • T7596Firocoxib;非罗考昔ML 1785713;非罗考昔|||ML 1785713

    Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.

    价 格:¥电议型 号:T7596产 地:中国大陆

  • T75713Human growth hormone-releasing factor TFA;化合物 Human growth hormone-releasing factor TFAHuman growth

    Human Growth Hormone-Releasing Factor TFA, also known as Growth Hormone-Releasing Factor Human TFA, is a hypothalamic polypeptide that promotes the production and release of growth hormone (GH) through its interaction with the Growth Hormone-Releasing Hormone Receptor (GHRHR) on anterior pituitary cells [1].

    价 格:¥电议型 号:T75713产 地:中国大陆

  • T74713TMV-IN-3;化合物 TMV-IN-3TMV-IN-3

    TMV-IN-3, a chalcone derivative, functions as a tobacco mosaic virus (TMV) inhibitor, exhibiting antiviral activity against TMV with an EC50 of 120.3 μg/mL. This compound is applicable for research in infection, inflammation, and tumor [1].

    价 格:¥电议型 号:T74713产 地:中国大陆

  • T73713Flupirtine-d4 hydrochloride;化合物 Flupirtine-d4 hydrochlorideFlupirtine-d4 hydrochloride

    Flupirtine-d4 (D 9998-d4) hydrochloride, the deuterium-labeled version of Flupirtine (D 9998) hydrochloride, is a selective neuronal potassium channel opener with additional NMDA receptor antagonist properties [1] [2].

    价 格:¥电议型 号:T73713产 地:中国大陆

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