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T71363ACT-281959;化合物 ACT-281959ACT-281959
ACT-281959, a prodrug of ACT-246475, is a novel potent and selective P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel. ACT-281959 showed antithrombotic efficacy after oral administration in the rat ferric chloride model. ACT-281959 entered clinical studies in healthy volunteers.
价 格:¥电议型 号:T71363产 地:中国大陆
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T71362GCC-4401C free base;化合物 GCC-4401C free baseGCC-4401C free base
GCC-4401C free base is a factor Xa inhibitor similar to rivaroxaban that is currently under development for venous thromboembolic disease (VTE).
价 格:¥电议型 号:T71362产 地:中国大陆
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T71361CHS-828 nicotinate;化合物 CHS-828 nicotinateCHS-828 nicotinate
CHS-828 nicotinate is a CHS-828 salt with Nicotinic acid.. CHS-828 also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting the nuclear factor-kappaB translocation but unlikely through down-regulation of proteasome. CHS 828 has shown promising anticancer activity in experimental tumor models and primary cultures of cancer cells from patients. CHS 828 showed a synergistic effect with melphalan in 67%,
价 格:¥电议型 号:T71361产 地:中国大陆
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T71360JNJ-39729209;化合物 JNJ-39729209JNJ-39729209
JNJ-39729209 is a TRPV1 antagonist.
价 格:¥电议型 号:T71360产 地:中国大陆
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T7136AZD-6280;化合物AZD6280AZD-6280
AZD6280 is a novel, subtype-selective GABAAα2/3 receptor positive modulators, used for treatment of generalized anxiety disorder.
价 格:¥电议型 号:T7136产 地:中国大陆
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T71359ArgTX-93 TFA;化合物 ArgTX-93 TFAArgTX-93 TFA
ArgTX-93 is a highly potent and subfamily selective antagonist of the NMDARs and AMPARs.
价 格:¥电议型 号:T71359产 地:中国大陆
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T71358Nialamide monohydrochloride;化合物 Nialamide monohydrochlorideNialamide monohydrochloride
Nialamide monohydrochloride is a non-selective, irreversible monoamine oxidase inhibitor (MAOI) of the hydrazine class that was used as an antidepressant. It was withdrawn by Pfizer several decades ago due to the risk of hepatotoxicity.
价 格:¥电议型 号:T71358产 地:中国大陆
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T71357AZD-3783;化合物 AZD-3783AZD-3783
AZD-3783 is a selective 5-hydroxytryptamine 1B receptor antagonist with probable antidepressant and anxiolytic activity.
价 格:¥电议型 号:T71357产 地:中国大陆
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T71356Lanperisone HCl;化合物 Lanperisone HClLanperisone HCl
Lanperisone, also known as NK433, is a muscle relaxant. NK433 inhibited the facilitation of the flexor reflex mediated by group II afferent fibers that was induced by intrathecal administration of noradrenaline-HCl. NK433 had effects more than three times stronger and tending to be longer-lasting than those of eperisone-HCl. These results suggest that NK433 exerts a non-selective inhibition on spinal reflexes and that inhibition of the descending noradrenergic tonic facilitation within the spina
价 格:¥电议型 号:T71356产 地:中国大陆
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T71355MDL-27788;化合物 MDL-27788MDL-27788
MDL-27788 is a tricyclic inhibitor.
价 格:¥电议型 号:T71355产 地:中国大陆
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T71354AMG-222 tosylate;化合物 AMG-222 tosylateAMG-222 tosylate
AMG-222 tosylate is a DPP-IV inhibitor in clinical development for type II diabetes.
价 格:¥电议型 号:T71354产 地:中国大陆
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T71353CCT239065;化合物 CCT239065CCT239065
CCT239065 is a novel, selective, and efficacious nanomolar pyridopyrazinone V600EBRAF and LCK inhibitor.
价 格:¥电议型 号:T71353产 地:中国大陆
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T71352MLS000099089;化合物 MLS000099089MLS000099089
MLS000099089 is a selective and potent inhibitor of recombinant human 12/15-LOX and cellular murine 12/15-LOX.
价 格:¥电议型 号:T71352产 地:中国大陆
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T71351STAT3-IN-A69;化合物 STAT3-IN-A69STAT3-IN-A69
STAT3-IN-A69 is an inhibitor targeting the DNA-binding domain of STAT3, suppressing tumor growth, metastasis and STAT3 target gene expression in vivo.
价 格:¥电议型 号:T71351产 地:中国大陆
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T71350Cinanserin;化合物 CinanserinCinanserin
Cinanserin is a serotonin 5-HT2 antagonist.
价 格:¥电议型 号:T71350产 地:中国大陆
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T7135Phenylbiguanide1-苯基双胍PBG|||N-Phenylbiguanide|||1-苯基双胍|||1-Phenylbiguanide
Phenylbiguanide (N-Phenylbiguanide) is a 5-HT3 receptor selective agonist(EC50 : 3.0±0.1 μM)
价 格:¥电议型 号:T7135产 地:中国大陆
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T71349GRC-6211;化合物 GRC-6211GRC-6211
GRC-6211 is an oral specific TRPV1 antagonist which decreases bladder overactivity and noxious bladder input in cystitis animal models.
价 格:¥电议型 号:T71349产 地:中国大陆
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T71348UC-773587;化合物 UC-773587UC-773587
UC-773587 is a novel inhibitor of Ras signaling, binding to the Ras switch II interaction region of SOS1.
价 格:¥电议型 号:T71348产 地:中国大陆
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T71347Galdansetron;化合物 GaldansetronGaldansetron
Galdansetron is a serotonin antagonist.
价 格:¥电议型 号:T71347产 地:中国大陆
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T71346MS4;化合物 MS4MS4
MS4 is a novel glucocorticoid receptor (GR) agonist with anti-inflammatory activity and displaying reduced impact on islets.
价 格:¥电议型 号:T71346产 地:中国大陆