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T73433MS47134;化合物 MS47134MS47134
MS47134, a selective and potent MRGPRX4 agonist, exhibits an EC50 of 149 nM and holds potential for researching pain, itch, and mast cell-mediated hypersensitivity.
价 格:¥电议型 号:T73433产 地:中国大陆
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T72713PI3K/VEGFR2-IN-1;化合物 PI3K/VEGFR2-IN-1PI3K/VEGFR2-IN-1
PI3K/VEGFR2-IN-1 is a potent dual inhibitor targeting both PI3K and VEGFR2 with IC50 values of 2.21 μM for PI3K and 68 μM for VEGFR2, respectively. This compound also induces apoptosis and is utilized in cancer research [1].
价 格:¥电议型 号:T72713产 地:中国大陆
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T71713Pirarubicin HCl;化合物 Pirarubicin HClPirarubicin HCl
Pirarubicin HCl is the hydrochloride salt form of pirarubicin, an analogue of the anthracycline antineoplastic antibiotic doxorubicin with antineoplastic activity. Pirarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines.
价 格:¥电议型 号:T71713产 地:中国大陆
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T71399Plogosertib;化合物 PlogosertibCYC140;CYC140
Plogosertib (CYC140) is an orally active, selective, potent, and ATP-competitive PLK1 inhibitor with an IC50 value of 3 nM.Plogosertib exhibits antiproliferative and anticancer activity and can be used for the study of solid and hematologic tumors.and hematologic tumors.
价 格:¥电议型 号:T71399产 地:中国大陆
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T71398RO5126946;化合物 RO5126946RO5126946
RO5126946 is a Novel α7 nicotinic acetylcholine receptor-positive allosteric modulator. RO5126946 allosterically modulates α7nAChR activity. RO5126946 increased acetylcholine-evoked peak current and delayed current decay but did not affect the recovery of α7nAChRs from desensitization. In addition, RO5126946´s effects were absent when nicotine-evoked currents were completely blocked by coapplication of the α7nAChR-selective antagonist methyl-lycaconitine.
价 格:¥电议型 号:T71398产 地:中国大陆
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T71397Setileuton tosylate;化合物 Setileuton tosylateSetileuton tosylate
Setileuton, also known as MK0633, is a potent and selective 5-lipoxygenase inhibitor which is under investigation for the treatment of asthma and atherosclerosis.
价 格:¥电议型 号:T71397产 地:中国大陆
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T71396FCE-24379;化合物 FCE-24379FCE-24379
FCE-24379 is a selective antagonist of vascular serotonin receptors that has been shown to lowers blood pressure in hypertensive rats.
价 格:¥电议型 号:T71396产 地:中国大陆
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T71395Rohinitib;化合物 RohinitibRohinitib
Rohinitib, a potent and specific eIF4A inhibitor, effectively induces apoptosis in acute myeloid leukemia (AML) cell lines and decreases the leukemia burden in AML xenograft models. This compound is utilized in the research of AML.
价 格:¥电议型 号:T71395产 地:中国大陆
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T71394BMS-823778;化合物 BMS-823778BMS-823778
BMS-823778 is a potent inhibitor of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1) for the study of type 2 diabetes.
价 格:¥电议型 号:T71394产 地:中国大陆
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T71393(S)-FTY-720 Vinylphosphonate;化合物 (S)-FTY-720 Vinylphosphonate(S)-FTY-720 Vinylphosphonate
(S)-FTY-720 Vinylphosphonate inhibits sphingosine kinase 1 and promotes its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer cells, and androgen-independent prostate cancer cells.
价 格:¥电议型 号:T71393产 地:中国大陆
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T71392(R)-FTY-720 Vinylphosphonate;化合物 (R)-FTY-720 Vinylphosphonate(R)-FTY-720 Vinylphosphonate
(R)-FTY-720 Vinylphosphonate is a sphingosine 1-phosphate type 1 (S1P1) receptor agonist and lacks anti-apoptotic activity.
价 格:¥电议型 号:T71392产 地:中国大陆
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T71391BRL 37344;化合物 BRL 37344BRL 37344
BRL 37344 is a beta 3-adrenoceptor agonist.
价 格:¥电议型 号:T71391产 地:中国大陆
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T71390AY 29315;化合物 AY 29315AY 29315
AY 29315 is a histamine H2-receptor antagonist with antisecretory and antiulcer activities.
价 格:¥电议型 号:T71390产 地:中国大陆
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T71389Fluoxetine oxalate;化合物 Fluoxetine oxalateFluoxetine oxalate
Fluoxetine oxalate is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the treatment of major depressive disorder, obsessive–compulsive disorder, bulimia nervosa, panic disorder, and premenstrual dysphoric disorder.
价 格:¥电议型 号:T71389产 地:中国大陆
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T71388Desaspidin;化合物 DesaspidinDesaspidin
Desaspidin is an anthelmintic. Desapidin may occur in natural form within some plants such as Coastal woodfern, Dryopteris arguta. Since the 1950s the inhibition effects of desapidins upon phosphorylation in chloroplasts has been noted and studied.
价 格:¥电议型 号:T71388产 地:中国大陆
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T71387Neratinib maleate monohydrate;化合物 Neratinib maleate monohydrateNeratinib maleate monohydrate
Neratinib maleate monohydrate is an irreversible inhibitor of the HER-2 receptor tyrosine kinase with potential antineoplastic activity.
价 格:¥电议型 号:T71387产 地:中国大陆
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T71386GW-597901 cinnamate;化合物 GW-597901 cinnamateGW-597901 cinnamate
GW-597901 cinnamate is a long-acting beta(2)-agonist.
价 格:¥电议型 号:T71386产 地:中国大陆
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T71385Aroplatin;化合物 AroplatinAroplatin
Aroplatin is a synthetic liposomal formulation of bis-neodecanoate diaminocyclohexane platinum (NDDP), a third-generation platinum complex analogue of cisplatin, with potential antineoplastic activity. After displacement of the 2 long-chain aliphatic leaving groups (neodecanoic acid), platinum diaminocyclohexane (DACH) complexes become highly reactive and alkylate macromolecules, forming both inter- and intra-strand DNA crosslinks and inhibiting DNA synthesis, which results in tumor cell cytotox
价 格:¥电议型 号:T71385产 地:中国大陆
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T71384Cenisertib benzoate;化合物 Cenisertib benzoateCenisertib benzoate
Cenisertib benzoate is an orally bioavailable, synthetic, small-molecule multi-Aurora kinase inhibitor with potential antineoplastic activity.
价 格:¥电议型 号:T71384产 地:中国大陆
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T71383NB-533;化合物 NB-533NB-533
NB-533 is a macrocyclic peptidic BACE-1 inhibitor.
价 格:¥电议型 号:T71383产 地:中国大陆