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T17885cIAP1 Ligand-Linker Conjugates 11；化合物 T17885E3 ligase Ligand-Linker Conjugates 33；E3 ligase Ligand-L
cIAP1 Ligand-Linker Conjugates 11 is a chemical compound that combines an IAP ligand specifically designed for the E3 ubiquitin ligase with a PROTAC linker. This compound, cIAP1 Ligand-Linker Conjugates 11, is useful in the development of SNIPERs[1], allowing for the targeted degradation of proteins.
价 格：￥电议型 号：T17885产 地：中国大陆
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T17884cIAP1 Ligand-Linker Conjugates 11 Hydrochloride；化合物 T17884E3 ligase Ligand-Linker Conjugates 33 Hydr
cIAP1 Ligand-Linker Conjugates 11 Hydrochloride is a chemical compound consisting of an IAP ligand that targets the E3 ubiquitin ligase, along with a PROTAC linker. It is primarily utilized in the development of SNIPERs, a molecular tool for targeted protein degradation[1].
价 格：￥电议型 号：T17884产 地：中国大陆
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T17883Pomalidomide-PEG3-C2-NH2；化合物Pomalidomide-PEG3-C2-NH2Cereblon Ligand-Linker Conjugates 5|||E3 ligase
Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide based cereblon ligand and 3-unit PEG linker.
价 格：￥电议型 号：T17883产 地：中国大陆
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T17882Pomalidomide-PEG3-C2-NH2 (TFA)；化合物 T17882Cereblon Ligand-Linker Conjugates 5 (TFA)|||E3 ligase Ligan
Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
价 格：￥电议型 号：T17882产 地：中国大陆
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T17880E3 ligase Ligand 9；化合物 T17880E3 ligase Ligand 9
E3 ligase Ligand 9 is a compound that serves as a ligand for E3 ubiquitin ligase. It can be linked to the protein ligand through a linker, forming PROTACs or SNIPERs. These PROTACs are known to induce the degradation of cancer-promoting proteins through ubiquitination-mediated mechanisms[1].
价 格：￥电议型 号：T17880产 地：中国大陆
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T17879E3 ligase Ligand 8；化合物E3 ligase Ligand 8E3 ligase Ligand 8
E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. The E3 ligase Ligand 8 can be linked to protein ligands through linkers to form PROTACs, which are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
价 格：￥电议型 号：T17879产 地：中国大陆
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T17878Lenalidomide-C4-NH2 hydrochloride；化合物 T17878Cereblon ligand 1 hydrochloride|||E3 ligase Ligand-Linke
Lenalidomide-C4-NH2 hydrochloride is a Cereblon ligand derived from Lenalidomide. It serves as a recruiting agent for the CRBN protein. The compound, known as PROTAC (Compound 24), can be formed by linking Lenalidomide-C4-NH2 hydrochloride to the ligand for the protein. It exhibits inhibitory effects with IC50s of 0.98 nM and 13.7 nM against the growth of RS4;11 and MOLM-13 acute leukemia cell lines, respectively[1].
价 格：￥电议型 号：T17878产 地：中国大陆
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T17877VH032-cyclopropane-F；化合物T17877VHL ligand 3|||E3 ligase Ligand 19|||Phenolic VH101；VHL ligand 3|||E3
VH032-cyclopropane-F (Phenolic VH101) is a VH032-based VHL ligand. VH032-cyclopropane-F can be connected to the ligand for protein by a linker to form PROTACs. PROTAC 1 is a partial degrader of SMARCA2 and SMARCA4.
价 格：￥电议型 号：T17877产 地：中国大陆
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T17876E3 ligase Ligand 18；化合物 T17876E3 ligase Ligand 18
E3 ligase Ligand 18 is a ligand that binds to E3 ubiquitin ligase, and it can be chemically attached to a protein ligand through a linker to create PROTACs. The resulting PROTACs function as inducers of ubiquitination-mediated degradation, targeting cancer-promoting proteins[1].
价 格：￥电议型 号：T17876产 地：中国大陆
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T17875Pomalidomide-C2-NH2；化合物T17875Cereblon Ligand-Linker Conjugates 15|||4-[(2-Aminoethyl)amino]-2-(2,6-d
Pomalidomide-C2-NH2 (4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is a synthesized E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.
价 格：￥电议型 号：T17875产 地：中国大陆
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T17874Nutlin carboxylic acid；化合物 T17874MDM2 ligand 1|||E3 ligase Ligand 16；MDM2 ligand 1|||E3 ligase Ligan
Nutlin Carboxylic Acid (MDM2 ligand 1), derived from Nutlin 3, serves as an MDM2 ligand. It can be attached to a protein ligand via a linker to create PROTACs[1].
价 格：￥电议型 号：T17874产 地：中国大陆
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T17872E3 ligase Ligand 14；化合物 T17872E3 ligase Ligand 14
E3 ligase Ligand 14 is a ligand that binds to E3 ubiquitin ligase and can be conjugated to a protein ligand via a linker to create PROTACs. These PROTACs are capable of promoting ubiquitination-mediated degradation of cancer-promoting proteins[1].
价 格：￥电议型 号：T17872产 地：中国大陆
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T17871E3 ligase Ligand 13；化合物 T17871E3 ligase Ligand 13
E3 ligase Ligand 13 is an E3 ubiquitin ligase ligand that can be employed to create PROTACs, which are connected to the ligand for the protein through a linker. PROTACs serve as inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
价 格：￥电议型 号：T17871产 地：中国大陆
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T17870cIAP1 ligand 1；cIAP1 配体1E3 ligase Ligand 12；E3 ligase Ligand 12
cIAP1 ligand 1 (E3 ligase Ligand 12) is an apoptotic protein ligand based on the LCL161 derivative that recruits IAP ubiquitin ligases to degrade target proteins, and can be used to couple with androgen receptor ligands for the development of protein degradation agents, which can be used in the study of prostate cancer.CAS ??13460-73-83-4
价 格：￥电议型 号：T17870产 地：中国大陆
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T17869cIAP1 ligand 2；化合物 T17869E3 ligase Ligand 11；E3 ligase Ligand 11
cIAP1 ligand 2, a derivative of LCL161, is an IAP ligand that can be connected to the ABL ligand for protein via a linker, resulting in the formation of SNIPER.
价 格：￥电议型 号：T17869产 地：中国大陆
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T17868E3 ligase Ligand 10；化合物 T17868E3 ligase Ligand 10
E3 ligase Ligand 10 serves as a ligand for E3 ubiquitin ligase and can be conjugated to a protein ligand through a linker, resulting in the formation of PROTACs. These PROTACs act as inducers of ubiquitination-mediated degradation, specifically targeting cancer-promoting proteins[1].
价 格：￥电议型 号：T17868产 地：中国大陆
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T17819Thalidomide-O-amido-C8-NH2；化合物 T17819E3 Ligase Ligand-Linker Conjugates 20|||Cereblon Ligand-Linker
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker. This compound is useful in the synthesis of PROTACs, as per reference [1].
价 格：￥电议型 号：T17819产 地：中国大陆
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T17818Thalidomide-O-amido-C4-NH2；化合物 T17818E3 Ligase Ligand-Linker Conjugates 19|||Cereblon Ligand-Linker
Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6) is a synthesized ligand-linker conjugate that combines a Thalidomide-based cereblon ligand with a linker. It functions as an E3 ligase ligand-linker conjugate and finds applications in the synthesis of PROTACs[1].
价 格：￥电议型 号：T17818产 地：中国大陆
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T17733ATRA-hydroxyimino；化合物 T17733CRABP-II ligand 1；CRABP-II ligand 1
ATRA-hydroxyimino, also known as CRABP-II ligand 1, is a chemical compound derived from Retinoic acid (ATRA). This compound binds to the cIAP1 ligand, specifically Bestatin, through a linker, resulting in the formation of a complex called SNIPER. The purpose of this complex is to degrade CRABP-II within IMR-32 cells[1].
价 格：￥电议型 号：T17733产 地：中国大陆
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T17727CCK2R Ligand-Linker Conjugates 1；化合物 T17727CCK2R Ligand-Linker Conjugates 1
CCK2R Ligand-Linker Conjugate 1 is a hydrophilic peptide linker that conjugates to the cytotoxic antimicrotubule agents Desacetyl Vinblastine Hydrazide (DAVBH) and Tubulysin B Hydrazide (TubBH) as ligand-linker conjugates[1].
价 格：￥电议型 号：T17727产 地：中国大陆
