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T17364AhR Ligand-Linker Conjugates 1；化合物 T17364E3 Ligase Ligand-Linker Conjugates 57；E3 Ligase Ligand-Link
AhR Ligand-Linker Conjugates 1, also known as E3 Ligase Ligand-Linker Conjugates 57, is a chemical compound that combines an IAP ligand for the E3 ubiquitin ligase with a SNIPER linker. It is specifically designed to be used in the development of SNIPER[1].
价 格：￥电议型 号：T17364产 地：中国大陆
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T17325Pomalidomide-PEG4-C-COOH；化合物Pomalidomide-PEG4-C-COOHCereblon Ligand -Linker Conjugates 1|||E3 Ligase
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
价 格：￥电议型 号：T17325产 地：中国大陆
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T15191PROTAC ERRα ligand 1；化合物PROTAC ERRα ligand 1PROTAC ERRα ligand 1
PROTAC ERRα ligand 1 is an α (ERRα) antagonist of estrogen-related receptor (IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively).
价 格：￥电议型 号：T15191产 地：中国大陆
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T15190L(S,R,S)-AHPC-PEG4-NH2；化合物T15190LVHL Ligand-Linker Conjugates 4|||E3 ligase Ligand-Linker Conjugates
(S,R,S)-AHPC-PEG4-NH2 (VHL Ligand-Linker Conjugates 4) is a synthetic E3 ligase ligand-linker conjugate comprising a VHL ligand based on (S,R,S)-AHPC and a 4-unit PEG linker.
价 格：￥电议型 号：T15190L产 地：中国大陆
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T15190(S,R,S)-AHPC-PEG4-NH2 hydrochloride；化合物 T15190E3 ligase Ligand-Linker Conjugates 7|||VH032-PEG4-NH2
(S, R, S)-AHPC-PEG4-NH2 hydrochloride is a chemically synthesized conjugate consisting of an E3 ligase ligand-linker, incorporating the VHL ligand based on (S, R, S)-AHPC, and a 4-unit PEG linker, which are specifically designed for use in PROTAC technology.
价 格：￥电议型 号：T15190产 地：中国大陆
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T15189Thalidomide-O-amido-C4-N3；化合物Thalidomide-O-amido-C4-N3E3 ligase Ligand-Linker Conjugates 18|||Cerebl
Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.
价 格：￥电议型 号：T15189产 地：中国大陆
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T13958VHL Ligand 8；化合物 T13958VHL Ligand 8
VHL Ligand 8, a VHL ligand essential for synthesizing ARD-266, acts as a highly potent VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. It efficiently facilitates the degradation of AR protein in AR-positive prostate cancer cell lines LNCaP, VCaP, and 22Rv1, exhibiting DC50 values ranging from 0.2-1 nM [1].
价 格：￥电议型 号：T13958产 地：中国大陆
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T13906STING ligand-1；化合物 T13906STING ligand-1
STING ligand-1 is a lead STING ligand(IC50 of 68 nM for HAQ STING).
价 格：￥电议型 号：T13906产 地：中国大陆
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T13890SMARCA-BD ligand 1 for Protac dihydrochloride；化合物T13890SMARCA-BD ligand 1 for Protac dihydrochloride
SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.
价 格：￥电议型 号：T13890产 地：中国大陆
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T13876(S,R,S)-AHPC-propargyl；化合物 T13876(S,R,S) AHPC propargyl|||VHL ligand 7|||AHPC-propargyl|||VH032-prop
(S,R,S)-AHPC-propargyl is a VHL ligand which is used in "click reaction" for PROTACs.
价 格：￥电议型 号：T13876产 地：中国大陆
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T13848SMARCA-BD ligand 1 for Protac；化合物SMARCA-BD ligand 1 for ProtacSMARCA-BD ligand 1 for Protac
SMARCA-BD ligand 1 for Protac is a compound capable of binding to SMARCA2, the BAF ATPase subunit, based on the Protac technology for degrading SMARCA2
价 格：￥电议型 号：T13848产 地：中国大陆
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T13843PROTAC IRAK4 ligand-1；化合物 T13843PROTAC IRAK4 ligand-1
PROTAC IRAK4 ligand-1 is a synthetic ligand for interleukin-1 receptor-associated kinase 4.
价 格：￥电议型 号：T13843产 地：中国大陆
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T13832PROTAC BCR-ABL1 ligand 1；化合物 T13832PROTAC BCR-ABL1 ligand 1
PROTAC BCR-ABL1 ligand 1 is the ligand of PROTAC .
价 格：￥电议型 号：T13832产 地：中国大陆
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T13813PCSK9 ligand 1；化合物 T13813PCSK9 ligand 1
PCSK9 ligand 1 is a small molecule ligand for proprotein convertase substilisin-like/kexin type 9 (PCSK9) and shows high affinity to PCSK9(Ki of 107 nM).
价 格：￥电议型 号：T13813产 地：中国大陆
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T13671L(S,R,S)-AHPC-Me dihydrochloride；化合物 T13671LVHL ligand 2 dihydrochloride|||E3 ligase Ligand 1 dihydro
(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound utilized in the synthesis of ARV-771. ARV-771, a BET PROTAC degrader relying on von Hippel-Landau (VHL) E3 ligase, demonstrates potent degradation of BET protein in castration-resistant prostate cancer (CRPC) cells, with a DC50 of less than 1 nM. This compound serves as the VHL ligand, specifically the (S,R,S)-AHPC-based VHL ligand, that facilitates the recruitment of von Hippel-Lindau (VHL) prote
价 格：￥电议型 号：T13671L产 地：中国大陆
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T13671(S,R,S)-AHPC-Me hydrochloride；化合物(S,R,S)-AHPC-Me hydrochlorideVHL ligand 2 hydrochloride|||E3 ligase
(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is a chemical compound utilized in the synthesis of ARV-771, an exceptionally potent BET protein degrader. This compound selectively degrades BET protein in cells resistant to castration, exhibiting a remarkable DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, (S,R,S)-AHPC-Me hydrochloride serves as the VHL ligand derived from (S,R,S)-AHPC for the recruitment of von Hippel-Lindau (VHL) protein.
价 格：￥电议型 号：T13671产 地：中国大陆
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T13510Sigma-LIGAND-1；化合物Sigma-LIGAND-1Sigma-LIGAND-1
Sigma-LIGAND-1 is a selective Sigma Receptor ligand with an IC50s of 16 nM, 19 nM at the DTG site and the PPP site, respectively. Sigma-LIGAND-1 has a Ki of 4000 nM at the dopamine D2 receptor.
价 格：￥电议型 号：T13510产 地：中国大陆
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T12551PROTAC BRD4 ligand-1；化合物PROTAC BRD4 ligand-1PROTAC BRD4 ligand-1
PROTAC BRD4 ligand-1 is a ligand for BRD4 for Protac GNE-987 and an inhibitor of BET.
价 格：￥电议型 号：T12551产 地：中国大陆
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T10734CDK ligand for PROTAC；化合物 T10734CDK ligand for PROTAC
CDK ligand for PROTAC is a CDK inhibitor with antitumor activity. It has been used to design PROTAC CDK4/6 degraders.
价 格：￥电议型 号：T10734产 地：中国大陆
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T10716CCR7 Ligand 1；化合物 T10716CCR7-Cmp2105；CCR7-Cmp2105
CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM.
价 格：￥电议型 号：T10716产 地：中国大陆
