当前位置：易推广 > 上海陶术生物科技有限公司 > 产品展示
企业档案
会员类型：会员
已获得易推广信誉 等级评定
(0 -40)基础信誉积累，可浏览访问
(41-90)良好信誉积累，可接洽商谈
(91+ )优质信誉积累，可持续信赖
易推广会员：5年
工商认证 【已认证】
最后认证时间：
注册号： 【已认证】
法人代表： 【已认证】
企业类型：生产商 【已认证】
注册资金：人民币万 【已认证】
产品数：86101
参观次数：3227901
自主品牌
已选条件
-
T79573ET receptor antagonist 1；化合物 ET receptor antagonist 1ET receptor antagonist 1
ET Receptor Antagonist 1 (compound 16h), with an IC50 value of 0.18 nM, is an orally active agent that can be utilized for pulmonary arterial hypertension (PAH) research. It has demonstrated efficacy in mitigating monocrotaline-induced PAH in a rat model [1].
价 格：￥电议型 号：T79573产 地：中国大陆
-
T79464RORγ antagonist 1；化合物 RORγ antagonist 1RORγ antagonist 1
RORγ antagonist 1 (compound 22), a potent derivative of betulinic acid, acts as an antagonist to RORγ with a dissociation constant (K D) of 0.18 μM. It demonstrates anti-proliferative effects in the HPAF-II pancreatic cancer xenograft model, inhibits the RAS/MAPK and AKT/mTORC1 signaling pathways, and triggers caspase-dependent apoptosis in pancreatic cancer cells [1].
价 格：￥电议型 号：T79464产 地：中国大陆
-
T79431Mu opioid receptor antagonist 7；化合物 Mu opioid receptor antagonist 7Mu opioid receptor antagonist 7
Compound 24, also known as Mu opioid receptor antagonist 7, is a potent, centrally-acting ?-opioid receptor (?OR) antagonist with an inhibitory concentration (IC50) of 29 ± 3.0 nM. It is valuable for pain and opioid use disorder research [1].
价 格：￥电议型 号：T79431产 地：中国大陆
-
T79418BLT2 antagonist-1；化合物 BLT2 antagonist-1BLT2 antagonist-1
BLT2 antagonist-1 (compound 15b) is a selective inhibitor of the BLT2 receptor, impeding the chemotaxis of CHO-BLT2 cells at an IC50 of 224 nM, while not affecting CHO-BLT1 cell chemotaxis. It blocks the interaction between LTB4 and the BLT2 receptor with a K_i of 132 nM and may serve as a research tool for inflammatory airway diseases, including asthma and chronic obstructive pulmonary disease [1].
价 格：￥电议型 号：T79418产 地：中国大陆
-
T79375NMDA receptor antagonist 8；化合物 NMDA receptor antagonist 8NMDA receptor antagonist 8
Compound (R)-10a, an NMDA receptor antagonist, exhibits selectivity for the GluN2B subunit, possessing a Ki of 265 nM and an IC50 of 62 nM. This compound is utilized in research pertaining to neurodegenerative diseases [1].
价 格：￥电议型 号：T79375产 地：中国大陆
-
T79374NMDA receptor antagonist 7；化合物 NMDA receptor antagonist 7NMDA receptor antagonist 7
Compound (S)-10a, a GluN2B subunit-selective NMDA receptor antagonist, exhibits a K i of 93 nM and an IC 50 of 72 nM. It is potentially useful for research into neurodegenerative diseases [1].
价 格：￥电议型 号：T79374产 地：中国大陆
-
T79273NMDA receptor antagonist 6；化合物 NMDA receptor antagonist 6NMDA receptor antagonist 6
NMDA Receptor Antagonist 6 (Compound 13b) functions as an antagonist at the glycine-binding site of the NMDA receptor and demonstrates cytoneuroprotective efficacy. It safeguards PC12 cells from NMDA-induced damage and apoptosis [1].
价 格：￥电议型 号：T79273产 地：中国大陆
-
T79184FKBP51F67V-selective antagonist Ligand2；化合物 FKBP51F67V-selective antagonist Ligand2FKBP51F67V-select
FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 or FKBP52 [1]. It effectively reverses the anxiogenic phenotype resulting from FKBP51 F67V overexpression in the amygdala.
价 格：￥电议型 号：T79184产 地：中国大陆
-
T79115P2X3 antagonist 38；化合物 P2X3 antagonist 38P2X3 antagonist 38
Compound 38, also known as Compound 4, is a potent, orally active P2X3 antagonist that demonstrates inhibitory activity with IC50 values of 0.132 ?M, 0.165 ?M, and 0.421 ?M against human (hP2X3), rat (rP2X3), and guinea pig (gpP2X3) P2X3 receptors, respectively [1].
价 格：￥电议型 号：T79115产 地：中国大陆
-
T79071HPK1 antagonist-1；化合物 HPK1 antagonist-1HPK1 antagonist-1
HPK1 antagonist-1 (I-792) is an inhibitor targeting HPK1, with potential applications in cancer and immune disease research [1].
价 格：￥电议型 号：T79071产 地：中国大陆
-
T79027A1/A3 AR antagonist 3；化合物 A1/A3 AR antagonist 3A1/A3 AR antagonist 3
A1/A3 AR Antagonist 3 is a dual A1R/A3R antagonist that demonstrates high affinity within the low-micromolar to nanomolar range, and is potentially useful in the research of chronic heart diseases [1].
价 格：￥电议型 号：T79027产 地：中国大陆
-
T79023CaSR antagonist-1；化合物 CaSR antagonist-1CaSR antagonist-1
CaSR Antagonist-1 is a potent inhibitor of the calcium-sensing receptor (CaSR) with an inhibitory concentration (IC50) of 50 nM, suitable for the investigation of diseases related to dysregulated bone or mineral homeostasis, including osteoporosis [1].
价 格：￥电议型 号：T79023产 地：中国大陆
-
T79002FITC-labeled ODN TTAGGG sodium；化合物 FITC-labeled ODN TTAGGG sodiumFITC-labeled ODN TTAGGG sodium
FITC-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide that functions as an antagonist of TLR9, AIM2, and cGAS. This compound facilitates the assessment of CpG ODN cellular uptake and localization via confocal laser-scanning microscopy (excitation at 495 nm, emission at 520 nm) or flow cytometry.
价 格：￥电议型 号：T79002产 地：中国大陆
-
T79001Biotin-labeled ODN TTAGGG sodium；化合物 Biotin-labeled ODN TTAGGG sodiumBiotin-labeled ODN TTAGGG sodiu
Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that functions as an antagonist to TLR9, AIM2, and cGAS. It serves as a tool for assessing cellular uptake and localization of CpG ODN using biotin detection systems and light microscopy.
价 格：￥电议型 号：T79001产 地：中国大陆
-
T78779D3R/MOR antagonist 2；化合物 D3R/MOR antagonist 2D3R/MOR antagonist 2
Compound 121, a D3R/MOR antagonist with K i values of 361 nM and 85.2 nM for D3R and MOR respectively, has the potential for analgesic effects through MOR partial agonism and may reduce opioid-misuse liability through D3R antagonism [1].
价 格：￥电议型 号：T78779产 地：中国大陆
-
T78778D3R/MOR antagonist 1；化合物 D3R/MOR antagonist 1D3R/MOR antagonist 1
Compound 114 (D3R/MOR antagonist 1) exhibits dual antagonistic activity at dopamine D3 receptors (D3R) and mu-opioid receptors (MOR), with K i values of 46.5 nM and 691 nM, respectively. It offers analgesic benefits through partial agonism at MOR and may decrease the risk of opioid misuse through its D3R antagonistic properties [1].
价 格：￥电议型 号：T78778产 地：中国大陆
-
T78735D1R antagonist 1；化合物 D1R antagonist 1D1R antagonist 1
Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].
价 格：￥电议型 号：T78735产 地：中国大陆
-
T78734Sigma-1 receptor antagonist 5；化合物 Sigma-1 receptor antagonist 5Sigma-1 receptor antagonist 5
Sigma-1 receptor antagonist 5 (compound 12), a 4-pyridylpiperidine derivative, exhibits analgesic properties through its antagonistic action on sigma receptors (Ki=4.5 nM (σ1R), 10 nM (σ2R)) and the histamine H3 receptor (hH3R, Ki=7.7 nM, IC50=215 nM). It effectively attenuates Capsaicin-induced nociception and demonstrates significant antinociceptive effects in both nociceptive and neuropathic pain models [1].
价 格：￥电议型 号：T78734产 地：中国大陆
-
T78678LTB4 antagonist 3；化合物 LTB4 antagonist 3LTB4 antagonist 3
Compound 24e, a leukotriene B4 (LTB4) antagonist, exhibits an inhibitory concentration 50 (IC50) of 477 nM and demonstrates anti-inflammatory activity [1].
价 格：￥电议型 号：T78678产 地：中国大陆
-
T78677LTB4 antagonist 2；化合物 LTB4 antagonist 2LTB4 antagonist 2
LTB4 antagonist 2, a carboxamide-acid compound, serves as an antagonist to leukotriene B4 (LTB4), possessing potential anti-inflammatory properties. It exhibits high affinity for the LTB4 receptor, with an inhibitory concentration (IC50) of 439 nM [1].
价 格：￥电议型 号：T78677产 地：中国大陆
