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T5622AHR antagonist 1AHR antagonist 1
AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist , has an IC50 of 39.9 nM in human cell line.
价 格:¥电议型 号:T5622产 地:美洲
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T5698TRPM8 antagonist 2TRPM8 antagonist 2
TRPM8 antagonist 2 is a potent and selective TRPM8 antagonist, with an IC50 of 0.2 nM, used in the research of neuropathic pain syndromes.
价 格:¥电议型 号:T5698产 地:美洲
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T5829H4 Receptor antagonist 1H4 Receptor antagonist 1
H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.
价 格:¥电议型 号:T5829产 地:美洲
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T5962N-Ethyl-p-menthane-3-carboxamideN-Ethyl-p-menthane-3-carboxamide,TRPM8 antagonist WS-3,Cyclohexaneca
N-Ethyl-p-menthane-3-carboxamide is an agonist of TRPM8( EC50 : 3.7 μM).
价 格:¥电议型 号:T5962产 地:美洲
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T8649TMBIM6 antagonist-1;1-(2-氨基苯基)-3-(3-硝基苯基)-2-丙烯-1-酮BAX-inhibitor-1|||BIA;BAX-inhibitor-1|||1-(2-氨基苯基)
TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitor
价 格:¥电议型 号:T8649产 地:中国大陆
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T84384i;化合物4iCHEMBL1269981|||5-HT3 antagonist-4i;CHEMBL1269981|||5-HT3 antagonist-4i
4i (CHEMBL1269981) is a 5-HT3 receptor antagonist,It modulates the serotonergic system.
价 格:¥电议型 号:T8438产 地:中国大陆
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T83972NOX-6-18;化合物 NOX-6-18GPR132 antagonist 1|||GPR132-B-160;GPR132 antagonist 1|||GPR132-B-160
NOX-6-18 (GPR132-B-160) is a highly potent and selective GPR132 antagonist with insulinotropic activity that modulates macrophage reprogramming in pancreatic islets and reduces weight gain.
价 格:¥电议型 号:T83972产 地:中国大陆
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T838458-(4-azidophenacylthio) NAD+ sodium;化合物 8-(4-azidophenacylthio) NAD+ sodiumClick Tag? 8-(4-azidophen
8-(4-Azidophenacylthio) NAD+ is a clickable variant of the essential signaling molecule and enzyme cofactor, NAD+.
价 格:¥电议型 号:T83845产 地:中国大陆
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T83779EP4 Antagonist 14;化合物 EP4 Antagonist 14Prostaglandin E2 Receptor 4 Antagonist 14|||PGE2 Receptor 4 A
EP4 antagonist 14 is a prostaglandin E2 receptor subtype EP4 antagonist, demonstrating an IC50 of 1.1 nM in a HEK293 human receptor reporter assay and blocking β-arrestin recruitment due to PGE2 with an IC50 of 0.9 nM. At 10 ?M, it reduces PGE2-stimulated mRNA levels of Il-4, macrophage mannose receptor 1 (Mrc1), chitinase-like protein 3 (Chil3), chemokine (C-X-C) motif ligand 1 (Cxcl1), triggering receptor expressed on myeloid cells 2 (Trem2), and arginase-1 (Arg1) in RAW 264.7 macrophages. Whe
价 格:¥电议型 号:T83779产 地:中国大陆
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T83773Prostaglandin E2 Inhibitor 3;化合物 Prostaglandin E2 Inhibitor 3PGE2 Inhibitor 3;PGE2 Inhibitor 3
Prostaglandin E2 (PGE2) inhibitor 3 is a selective inhibitor targeting microsomal prostaglandin E synthase-1 (mPGES-1; IC50 = 0.2 ?M), demonstrating greater selectivity for mPGES-1 over COX-1, COX-2, 5-lipoxygenase (5-LO), and soluble epoxide hydrolase (sEH) in assays at 10 ?M. This compound effectively reduces IL-1β-induced PGE2 production in A549 cells and decreases LPS-induced IL-6 and PGE2 in J774A.1 macrophages at concentrations of 10 and 1 ?M, respectively. Additionally, it blocks the prod
价 格:¥电议型 号:T83773产 地:中国大陆
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T836622,3-dinor-8-iso Prostaglandin F1α;化合物 2,3-dinor-8-iso Prostaglandin F1α2,3-dinor-8-iso PGF1α|||2,3-d
2,3-Dinor-8-iso Prostaglandin F1α (2,3-dinor-8-iso PGF1α), an isoprostane and active metabolite of arachidonic acid deriving its formation from non-enzymatic free radical peroxidation, acts as an active metabolite of the platelet aggregation inhibitor 8-iso PGF2α. This compound exhibits vasoconstrictive properties in isolated porcine retinal and brain microvessels with EC50 values of 12.8 and 18.5 nM, respectively, yet it does not cause contraction in isolated rat aortic rings at a concentration
价 格:¥电议型 号:T83662产 地:中国大陆
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T833433x DYKDDDDK Tag;化合物 3x DYKDDDDK Tag3x DYKDDDDK Tag
3x FLAG-DYKDDDDK Tag is a versatile tool utilized for studying protein function and localization when specific antibodies (Abs) are unavailable. It is frequently employed in its 3x FLAG format to facilitate the purification of proteins present in low quantities [1] [2].
价 格:¥电议型 号:T83343产 地:中国大陆
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T833423X HA Tag;化合物 3X HA Tag3X HA Tag
3X HA Tag is an active biological peptide that facilitates the detection and functional analysis of proteins and peptides of interest.
价 格:¥电议型 号:T83342产 地:中国大陆
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T832895-HT6R antagonist 2;化合物 5-HT6R antagonist 25-HT6R antagonist 2
Compound 29 is a 5-HT6R antagonist that acts by inhibiting the 5-HT6 receptor.
价 格:¥电议型 号:T83289产 地:中国大陆
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T83119Androgen receptor antagonist 9;化合物 Androgen receptor antagonist 9Androgen receptor antagonist 9
Androgen Receptor Antagonist 9 (compound 28) serves as an antagonist to the androgen receptor [1].
价 格:¥电议型 号:T83119产 地:中国大陆
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T8294Quercetagitrin万寿菊苷万寿菊苷|||槲皮万寿菊素-7-O-Β-吡喃葡萄糖苷|||Quercetagetin-7-O-glucoside
Quercetagitrin (Quercetagetin-7-O-glucoside), isolated from the African Marigold (Tagetes erecta), has anti-inflammatory activity.
价 格:¥电议型 号:T8294产 地:中国大陆
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T82797C5aR1 antagonist peptide;化合物 C5aR1 antagonist peptideC5aR1 antagonist peptide
C5aR1 antagonist peptide, a biologically active linear peptide originating from the C-terminus of the chemokine complement fragment 5 anaphylatoxin (C5a), inhibits C5a binding and activity at human and rat C5a receptors. Overexpression of C5a is linked to various immunoinflammatory diseases, including arthritis, Alzheimer’s disease, cystic fibrosis, and systemic lupus erythematosus.
价 格:¥电议型 号:T82797产 地:中国大陆
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T82772CB2 receptor antagonist 2;化合物 CB2 receptor antagonist 2CB2 receptor antagonist 2
Compound 39, also known as CB2 receptor antagonist 2, is a potent CB2 antagonist exhibiting an IC50 of 0.33 μM. It engages in strong interactions with residues L17, W6.48, V6.51, and C7.42 [1].
价 格:¥电议型 号:T82772产 地:中国大陆
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T82703CMKLR1 antagonist 1;化合物 CMKLR1 antagonist 1CMKLR1 antagonist 1
CMKLR1 antagonist 1 (compound S-26d) is a potent, orally active antagonist of the chemokine-like receptor 1 (CMKLR1), exhibiting a pIC50 of 7.44 in hCMKLR1-transfected CHO cells. It is applicable in the research of psoriasis and metabolic diseases [1].
价 格:¥电议型 号:T82703产 地:中国大陆