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产品数:86101
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T7130Navarixininhibit,CXC chemokine receptors,Inhibitor,MK 7123,Navarixin,SCH527123,SCH-527123,MK7123,CXC
Navarixin(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in animal models, characteristics that may be beneficial in the treatment of conditions with unbalanced pulmonary neutrophilia.
价 格:¥电议型 号:T7130产 地:中国大陆
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TQ0259AtrasentanAtrasentan,Endothelin Receptor,A 147627,ABT627,Inhibitor,inhibit,A147627,ABT 627
Atrasentan (ABT-627) is an endothelin receptor antagonist (IC50: 0.0551 nM for ETA).
价 格:¥电议型 号:TQ0259产 地:中国大陆
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T27328FL104FL104
FL104 is a potent agonist of small-molecule urotensin II receptor, pEC50= 7.11.
价 格:¥电议型 号:T27328产 地:中国大陆
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T2782CatharanthineCalcium Channel,Ca2+ channels,Ca channels,Inhibitor,Catharanthine,inhibit
Catharanthine suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM).
价 格:¥电议型 号:T2782产 地:中国大陆
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TP2158L1TRV-120027 acetate (1234510-46-3 free base)TRV120027 acetate (1234510463 free base),TRV 120027 aceta
TRV-120027 acetate is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1 receptor) and engages -arrestins while blocking G-protein signaling.
价 格:¥电议型 号:TP2158L1产 地:中国大陆
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T4118SB 271046 hydrochlorideoral,test,Serotonin Receptor,SB271046,5-HT Receptor,Inhibitor,inhibit,5-hydro
SB 271046 hydrochloride is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and < 4.99 at 5-HT1B, 5-HT1F, α1B, 5-HT2C, 5-HT2A, D2, 5-HT2B, 5-HT7, 5-HT4 and 5-HT1E respectively) and is > 200-fold selective over 55 other receptors, enzymes and ion channels. It increases extracellular aspartate and glutamate in the frontal cortex and exhibits anticonvulsant activity (EC50:
价 格:¥电议型 号:T4118产 地:中国大陆
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T8914MFCD01827729MFCD01827729,MFCD-01827729
MFCD01827729 is a chemical compound.
价 格:¥电议型 号:T8914产 地:中国大陆
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T6S1027TussilagoneTussilagone,anti-inflammatory,puncture,dextran,murine,ligation,colitis,cecal,inhibit,sulp
1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human colon cancer. 3. Tussilagone has anti-oxidant and anti-inflammatory activities, may be an effective oxygenase-1 inducer and a valuable compound for modulating inflammatory conditions. 4. Tussilagone has potential treatment of neuro-inflammatory diseases through the inhibition of ov
价 格:¥电议型 号:T6S1027产 地:中国大陆
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T9357Ro 5212773Ro-5212773,Inhibitor,Ro 5212773,neuronal,inhibit,Ro5212773,mesolimbic,system,TAAR1,GPCR
EPPTB is a selective TAAR1 antagonist.
价 格:¥电议型 号:T9357产 地:中国大陆
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T12758Ro 25-6981Ro 256981,Ro 25 6981
Ro 25-6981 is a potent and selective activity-dependent NMDA receptors blocker containing the NR2B subunit with IC50s of 0.009 and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively. Ro 25-6981 can be used in studies about Parkinson´s disease.
价 格:¥电议型 号:T12758产 地:中国大陆
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T25327Didemnin B
Didemnin B is a depsipeptide extracted from the marine tunicate Trididemnin cyanophorum that has antiviral and antitumor activity.
价 格:¥电议型 号:T25327产 地:中国大陆
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T8276Methyl palmitoleateacid,Palmitoleate,ester,Methyl palmitoleate,Inhibitor,fatty,methyl,inhibit,cytopr
Palmitoleic acid methyl ester is an ester version of palmitoleic acid, an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue.
价 格:¥电议型 号:T8276产 地:中国大陆
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T27471GSK299115AGSK299115A
GSK299115A is a selective ROCK1 Inhibitor. GSK299115A exhibits IC50 of 8nM, 620nM, 560nM for ROCK1, RSK1, p70S6K, respectively.
价 格:¥电议型 号:T27471产 地:中国大陆
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TJO2758D-Glucuronic acid1700908,Endogenous Metabolite,D Glucuronic acid,DGlucuronic acid,D-Glucuronic acid,
Glucuronic Acid is a carboxylic acid with structural similarity to glucose with detoxifying activity. The xenobiotic metabolism of various substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids, fatty acid derivatives, retinoids, and bile acids involves glucuronidation, a process in which water-soluble, excretable glucuronides of these substances are formed via glycosidic linkages to glucuronic acid. UDP-glucuronic acid, formed in the liver thr
价 格:¥电议型 号:TJO2758产 地:中国大陆
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TN2277Torachrysone-8-O-b-D-glucosideTorachrysone8ObDglucoside,Inhibitor,inhibit,Torachrysone 8 O b D gluco
Torachrysone 8-O-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes.
价 格:¥电议型 号:TN2277产 地:中国大陆
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T8858DTHIBdegradation,HSP27,Inhibitor,inhibit,HSP70,HSF1,HSP,DTHIB,HSP90,cancer,nuclear,anticancer,Heat s
DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.
价 格:¥电议型 号:T8858产 地:中国大陆
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TWO2759ThymineInhibitor,Thymine,Endogenous Metabolite,inhibit
One of the pyrimidine bases of living matter. Derivation: Hydrolysis of deoxyribonucleic acid, from methylcyanoacetylurea by catalytic reduction. Use: Biochemical research. Thymine is a pyrimidine nucleobase. As the name implies, thymine may be derived by methylation of uracil at the 5th carbon. Thymine is found in the nucleic acid DNA. In RNA thymine is replaced with uracil in most cases. In DNA, thymine binds to adenine via two hydrogen bonds to assist in stabilizing the nucleic acid structure
价 格:¥电议型 号:TWO2759产 地:中国大陆
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TJO2795D-Galacturonic acid hydrateinhibit,Endogenous Metabolite,Inhibitor,D Galacturonic acid hydrate,DGala
Used in the synthesis of N-(D-galacturonoyl) amino acids and dipeptides.
价 格:¥电议型 号:TJO2795产 地:中国大陆
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TP2279LObestatin (rat) acetateObestatin (rat) acetate
Obestatin (rat) acetate is an endogenous ligand of G-protein coupled receptor 39 (GPR39). Obestatin (rat) acetate has anti-inflammatory, anti-myocardial infarction and antioxidant properties. Obestatin (rat) acetate suppresses food intake, inhibits jejunal contraction, and decreases body-weight gain.
价 格:¥电议型 号:TP2279L产 地:中国大陆
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T9127MYLS22OPA1,Inhibitor,MYLS22,optic,atrophy,endothelial,MYLS-22,inhibit,MYLS 22,tumor
MYLS22 is a first-in-class and selective inhibitor of optic atrophy 1 (OPA1) . MYLS22 can target endothelial OPA1 to curtail tumor growth and inhibits angiogenesis by impinging on NFkB activity and on angiogenic gene expression. It with anti-angiogenesis and anti-cancer activity.
价 格:¥电议型 号:T9127产 地:中国大陆