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T6638RetapamulinRetapamulin,Bacterial,SB 275833,inhibit,SB275833,Inhibitor,Antibiotic
Retapamulin, a Pleuromutilin Antibacterial, binds to both E. coli and S. aureus ribosomes with similar potencies (Kd: 3 nM).
价 格:¥电议型 号:T6638产 地:中国大陆
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T9227Val-Ala-PABVal Ala PAB,ValAlaPAB
Val-Ala-PAB is a building block in the synthesis of Tesirine (a.k.a. SG3249), a clinical antibody-drug conjugate pyrrolobenzodiazepine dimer payload. Reagent in the preparation of pyrrolobenzodiazepine dimers and their antibody conjugates containing peptide linkers useful for treating proliferative including cancer.
价 格:¥电议型 号:T9227产 地:中国大陆
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T18018HS-27HS27,HS 27
HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC. HS-27 can be used in see-and-treat paradigms.
价 格:¥电议型 号:T18018产 地:中国大陆
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TQ0270Atrasentan hydrochlorideA 147627,A-147627,(+)-A 127722,Atrasentan hydrochloride,Atrasentan,ABT627,AB
Atrasentan hydrochloride is an antagonist of the endothelin receptor(IC50 = 55.1 μM for ETA).
价 格:¥电议型 号:TQ0270产 地:中国大陆
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T9500M435-1279M435 1279,M4351279
M435-1279 is a UBE2T inhibitor. M435-1279 blocks UBE2T-mediated degradation of RACK1, leading to inhibit the hyperactivation of Wnt/β-catenin signaling pathway.
价 格:¥电议型 号:T9500产 地:中国大陆
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T27854LSN2463359LSN2463359
LSN2463359 is a positive allosteric modulators of the mGlu5 receptor.
价 格:¥电议型 号:T27854产 地:中国大陆
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T6892Niraparib tosylatePARP,Niraparib tosylate,Apoptosis,inhibit,bioavailable,MK-4827,MK4827,cancer,damag
MK-4827(Niraparib) tosylate (with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
价 格:¥电议型 号:T6892产 地:中国大陆
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TWO27712-Adamantanol2 Adamantanol,2Adamantanol
2-Adamantanol was used to synthesize antiallergic drug Mizolastine.
价 格:¥电议型 号:TWO2771产 地:中国大陆
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T7738H3B-6527H-3B-6527,H3B6527,H3B 6527
H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma, with antineoplastic activity.
价 格:¥电议型 号:T7738产 地:中国大陆
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T37927Erucylamide
Erucylamide is an alkaloid found in Tadehagi triquetrum (L.) H.Ohashi.
价 格:¥电议型 号:T37927产 地:中国大陆
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T10827CK2/ERK8-IN-1
CK2/ERK8-IN-1 is a dual inhibitor of casein kinase 2 (CK2) (Ki: 0.25 ?M) and ERK8 (IC50s: 0.50 μM) with pro-apoptotic efficacy. CK2/ERK8-IN-1 also binds to PIM1, DYRK1A, and HIPK2 (Kis: 8.65 ?M, 11.9 ?M, and 15.25 ?M).
价 格:¥电议型 号:T10827产 地:中国大陆
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T27850LP-471756LP 471756
LP-471756 is a specific antagonist of GPR139 and inhibits LP-360924-stimulated cAMP production (IC50 = 640 nM).
价 格:¥电议型 号:T27850产 地:中国大陆
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T7155JH-II-127HEK293,JHII127,3T3 cells,Inhibitor,LRRK2-G2019S,Ser935,Leucine-rich repeat kinase 2,LRRK2,p
JH-II-127 is an orally inhibitor of leucine-rich repeat kinase 2 (LRRK2). It inhibits WT LRRK2, G2019S LRRK2 and A2016T LRRK2 (IC50s = 6.6, 2.2, and 47.7 nM, respectively),
价 格:¥电议型 号:T7155产 地:中国大陆
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T8527CPYPPDOCK2,CPYPP,Inhibitor,GEF,Rac1,DOCK180,lymphocytes,autoimmune,DOCK2-Rac1,inhibit,DOCK5,immunosu
CPYPP is an inhibitor of DOCK2-Rac1 interaction. CPYPP binds to DOCK2 DHR-2 domain and inhibits the guanine nucleotide exchange factor (GEF) activity of DOCK2DHR-2 for Rac1 in a dose-dependent manner(IC50 : 22.8 μM). CPYPP also inhibits DOCK180, DOCK5 and less DOCK9
价 格:¥电议型 号:T8527产 地:中国大陆
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T9527Span-85Span85,Span 85
Span is a synthetic non-ionic emulsifier, which is prepared by partial esterification of sorbitol or sorbitan with food grade palmitic acid. It has low viscosity and the smallest HLB value, so it has the strongest lipophilicity. It is an excellent water-in-oil (w/O) emulsifier and an O/w type auxiliary emulsifier.
价 格:¥电议型 号:T9527产 地:中国大陆
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T62769Tribendimidine
Tribendimidine is an orally active and broad-spectrum anthelmintic agent. Tribendimidine exhibits particularly high activity against A. lumbricoides and N. americanus. Tribendimidine is also an agonist of L-type nicotinic acetylcholine receptor (nAChR).
价 格:¥电议型 号:T62769产 地:中国大陆
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T27703JZP-361
JZP-361 is a specific MAGL inhibitor with IC50s of 46 nM, 7.24 μM, and 1.79 μM for human recombinant MAGL, human recombinant FAAH, and human hABHD6. JZP-361 displays anti-histaminergic activities. JZP-361 can be used in studies about asthma.
价 格:¥电议型 号:T27703产 地:中国大陆
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T82734,6-Dioxoheptanoic acidInhibitor,4,6-Dioxoheptanoic acid,inhibit,4,6Dioxoheptanoic acid,4,6 Dioxohep
4,6-Dioxoheptanoic acid acts as a potent inhibitor of heme biosynthesis.
价 格:¥电议型 号:T8273产 地:中国大陆
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T8327ONO-7475lung,tumor,leukemia,inhibit,solid,Trk Receptor,tolerant,cancer,Mer,Tropomyosin related kinas
ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinase
价 格:¥电议型 号:T8327产 地:中国大陆