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  • T40629Norswertianolin;NorswertianolinNorswertianolin

    Norswertianolin, a compound isolated from G. acuta, functions as a CSE activator and shows promise as a potential cardiovascular therapeutic.

    价 格:¥电议型 号:T40629产 地:中国大陆

  • T3S0629Delsoline;硬飞燕草碱Belsoline;Belsoline|||硬飞燕草碱

    1. Delsoline (Belsoline) has hypotensive effects.2. Delsoline is not only effective in preventing ventricular fibrillation and arrythmia, but can raise the intebsity of the threthold of electrical shocks to cause ventricular fibrillation in rabbits, the antiarrythmic effect of it may be mainly attributed to itsganglionic blocking and negative cardiac inotropic effect.

    价 格:¥电议型 号:T3S0629产 地:中国大陆

  • T39757EC2629;EC2629EC2629;EC2629

    EC2629 is a highly potent folate- receptor-targeted DNA crosslinking agent.

    价 格:¥电议型 号:T39757产 地:中国大陆

  • T39629BRD4 ligand-Linker Conjugate 1;BRD4 ligand-Linker Conjugate 1BRD4 ligand-Linker Conjugate 1;BRD4 lig

    BRD4 Ligand-Linker Conjugate 1 is a compound consisting of a ligand and a linker, specifically designed to bind to the target protein BRD4. This conjugate serves as a valuable tool for synthesizing PROTACs, molecules utilized for targeted protein degradation.

    价 格:¥电议型 号:T39629产 地:中国大陆

  • T38629Folate-PEG3-alkyne;Folate-PEG3-alkyneFolate-PEG3-alkyne;Folate-PEG3-alkyne

    Folate-PEG3-alkyne is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

    价 格:¥电议型 号:T38629产 地:中国大陆

  • T37732AMG 21629AMG 21629AMG 21629

    Potent and selective TRPV1 antagonist. Blocks Ca2+ uptake by CHO cells expressing TRPV1 receptors and acid-induced Ca2+ uptake, respectively). Exhibits >4000-fold selectivity for TRPV1 over other TRP channels. Blocks capsaicin-induced flinch response and causes hyperthermia in rats. Orally available and non-CNS penetrant.

    价 格:¥电议型 号:T37732产 地:中国大陆

  • T37113Z62954982;化合物 Z62954982ZINC08010136;ZINC08010136

    Z62954982 (ZINC08010136) is a selective inhibitor of Rac1, which stunts the growth and branching of neurons.Z62954982 inhibits Rac1 activation and reduces proliferation, p38 phosphorylation, and IL-6 levels in pulmonary arterioles.

    价 格:¥电议型 号:T37113产 地:中国大陆

  • T36629GivinostatGivinostat (ITF-2357)Givinostat

    Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively.

    价 格:¥电议型 号:T36629产 地:中国大陆

  • T36299Uridine triphosphate 13C9,15N2 sodium;Uridine triphosphate 13C9,15N2 sodiumUridine triphosphate 13C9

    Uridine triphosphate 13C9,15N2 (UTP 13C9,15N2) sodium, a labeled form of uridine triphosphate sodium, facilitates nucleic acid synthesis.

    价 格:¥电议型 号:T36299产 地:中国大陆

  • T36298Tyrocidine Complex;Tyrocidine ComplexTyrocidine Complex

    Tyrocidine complex is a mixture of cyclic decapeptides originally isolated from B. brevis. It is active against Gram-positive and Gram-negative bacteria. It forms a complex with single- and double-stranded DNA to inhibit RNA synthesis.

    价 格:¥电议型 号:T36298产 地:中国大陆

  • T36297Btk inhibitor 1 hydrochloride;Btk inhibitor 1 hydrochlorideBtk inhibitor 1 hydrochloride

    Btk inhibitor 1 Hcl is a pyrazolo[3,4-d]pyrimidine derivative as a Btk kinase inhibitor.

    价 格:¥电议型 号:T36297产 地:中国大陆

  • T36296BIO5192 hydrate;BIO5192 hydrateBIO5192 hydrate

    BIO5192 hydrate is a selective and potent integrin α4β1 (VLA-4) inhibitor (Kd<10 pM). BIO5192 hydrate selectively binds to α4β1 (IC50=1.8 nM) over a range of other integrins. BIO5192 hydrate results in a 30-fold increase in mobilization of murine hematopoietic stem and progenitors (HSPCs) over basal levels[1][2].

    价 格:¥电议型 号:T36296产 地:中国大陆

  • T36295Echistatin TFA;Echistatin TFAEchistatin TFA

    Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4].

    价 格:¥电议型 号:T36295产 地:中国大陆

  • T36294D-2-Aminoglutarimide (hydrochloride);D-2-Aminoglutarimide (hydrochloride)D-2-Aminoglutarimide (hydro

    D-2-Aminoglutarimide is a synthetic intermediate.1It has been used in the synthesis of hydantoins with anti-angiogenic and cancer cell differentiation-inducing activities.

    价 格:¥电议型 号:T36294产 地:中国大陆

  • T36293PAR 4 (1-6);PAR 4 (1-6)PAR 4 (1-6)

    PAR 4 (1-6) can be used for relevant research in the life sciences. Its product number is T36293 and CAS number is 225779-44-2.

    价 格:¥电议型 号:T36293产 地:中国大陆

  • T36292NSC 12;NSC 12NSC 12

    NSC 12 is an extracellular trap for fibroblast growth factor 2 (FGF2) that binds FGF2 (Kd = 51 μM) and interferes with its interaction with FGFR1, without affecting the ability of FGF2 to bind heparin or heparin sulfate proteoglycans (HSPGs). NSC 12 also binds several other, but not all, FGF isoforms with Kd values ranging between 16 and 120 μM, preventing them from forming HSPG/FGF/FGFR ternary complexes. NSC 12 inhibits FGF-dependent angiogenesis and tumor cell proliferation in vitro and reduc

    价 格:¥电议型 号:T36292产 地:中国大陆

  • T36291Integrin modulator 1;Integrin modulator 1Integrin modulator 1

    Integrin modulator 1 is a potent and selective α4β1 integrin agonist, with an IC50 of 9.8 nM for RGD-binding α4β1. Integrin modulator 1 increases cell adhesion mediated by α4β1 integrin, with an EC50 of 12.9 nM[1].

    价 格:¥电议型 号:T36291产 地:中国大陆

  • T3629Gamithromycin;加米霉素ML-1709460;ML-1709460|||加米霉素

    Gamithromycin (ML-1709460) is a macrolide compound with antibacterial activity.

    价 格:¥电议型 号:T3629产 地:中国大陆

  • T35629ATRA-BA HybridATRA-BA HybridATRABA Hybrid|||ATRA BA Hybrid

    ATRA-BA hybrid is a mutual prodrug form of all-transretinoic acid and butyric acid .1ATRA-BA hybrid is cleaved to release ATRA and BA in isolated mouse plasma. It inhibits the growth of MDA-MB-231 breast and PC3 prostate cancer cells with GI50values of 0.01 and 1.02 μM, respectively. ATRA-BA (20 μM) has 15-fold greater antiproliferative activity in PC3 cells compared to an equimolar concentration of ATRA and BA.

    价 格:¥电议型 号:T35629产 地:中国大陆

  • T35112WAY 126299A;化合物 T35112WAY126299A|||WAY-126299A;WAY126299A|||WAY-126299A

    Way 126299a is a dual-acting 5-lipoxygenase inhibitor and leukotriene D4 antagonist.

    价 格:¥电议型 号:T35112产 地:中国大陆

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