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T63505Tivozanib hydrochloride hydrate;Tivozanib 盐酸水合物AV-951 hydrochloride hydrate|||KRN951 hydrochloride h
Tivozanib hydrochloride hydrate (AV-951 hydrochloride hydrate) is an orally active, selective, and potent vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor that inhibits VEGFR-1, VEGFR-2, and VEGFR-3.
价 格:¥电议型 号:T63505产 地:中国大陆
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T63504Ziprasidone mesylate;化合物 Ziprasidone mesylateZiprasidone mesylate
Ziprasidone (CP-88059) mesylate is an orally active 5-HT and dopamine receptor antagonist. ziprasidone mesylate has affinity for D2, 5-HT2A and 5-HT1A in rats with Ki values of 4.8 nM, 0.42 nM and Ki=3.4 nM, respectively. 3.4 nM.
价 格:¥电议型 号:T63504产 地:中国大陆
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T63503CCT369260;化合物 CCT369260CCT369260
CCT369260 (compound 1), an orally active inhibitor targeting B-cell lymphoma 6 (BCL6), demonstrates anti-tumor efficacy with an IC50 value of 520 nM [1].
价 格:¥电议型 号:T63503产 地:中国大陆
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T63502KRAS G12C inhibitor 31;化合物 KRAS G12C inhibitor 31KRAS G12C inhibitor 31
KRAS G12C inhibitor 31 is an inhibitor of KRAS G12C that can be used to study cancer.
价 格:¥电议型 号:T63502产 地:中国大陆
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T63501KRAS G12C inhibitor 30;化合物 KRAS G12C inhibitor 30KRAS G12C inhibitor 30
KRAS G12C inhibitor 30 is an inhibitor of KRAS G12C and can be used to study cancer.
价 格:¥电议型 号:T63501产 地:中国大陆
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T63500Alexidine;化合物 AlexidineAlexidine
Alexidine is an antifungal and anti-biofilm agent against a variety of fungal pathogens. alexidine targets the mitochondrial tyrosine phosphatase PTPMT1 in mammalian cells, causing mitochondrial apoptosis and exhibiting antitumor effects.
价 格:¥电议型 号:T63500产 地:中国大陆
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T6350CHIR-124;化合物CHIR124CHIR124|||CHIR 124;CHIR124|||CHIR 124
CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.
价 格:¥电议型 号:T6350产 地:中国大陆
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T63263BM635 mesylate;化合物 BM635 mesylateBM635 mesylate
BM635 mesylate, an inhibitor of MmpL3, exhibited significant anti-Divergent bacterium effects, inhibiting and binding Divergent bacterium H37Rv with an MIC50 value of 0.6 μM. BM635 mesylate was able to significantly increase bioavailability compared to free BM635.
价 格:¥电议型 号:T63263产 地:中国大陆
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T62635Antifungal agent 30;化合物 Antifungal agent 30Antifungal agent 30
Antifungal agent 30 is a potent antifungal agent that exhibits good antifungal activity against Candida albicans (CPCC400616) (MIC: 0.03 μg/mL) and Aspergillus fumigatus (MIC: 0.5 μg/mL). Antifungal agent 30 exerts antifungal activity through hydrogen and ligand interactions with CYP51.
价 格:¥电议型 号:T62635产 地:中国大陆
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T62358BM635 hydrochloride;化合物 BM635 hydrochlorideBM635 hydrochloride
BM635 hydrochloride is an MmpL3 inhibitor that exhibits significant anti-Divergent bacteriophage effects, inhibiting the binding of Divergent bacteriophage H37Rv (MIC50: 0.08 μM). Exposure to BM635 hydrochloride was doubled in vivo compared to free BM635.
价 格:¥电议型 号:T62358产 地:中国大陆
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T61635hCAI/II-IN-4;化合物 hCAI/II-IN-4hCAI/II-IN-4
hCAI/II-IN-4 (compound 6d) is a powerful inhibitor of both hCA I and hCA II enzymes, with Ki values of 16.95 nM and 15.22 nM, respectively. It demonstrates inhibitory activity against hCA IX with a Ki value of 27.04 nM. Additionally, hCAI/II-IN-4 exhibits anti-hypoxia properties while maintaining low toxicity. This compound is suitable for investigating acute mountain sickness (AMS) in research studies [1].
价 格:¥电议型 号:T61635产 地:中国大陆
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T60635Simufilam hydrochloride;化合物 Simufilam hydrochlorideSimufilam hydrochloride
Simufilam (PTI-125) (hydrochloride) is an orally active filamin A (FLNA) activator with low toxicity that can be used in the Alzheimer´s disease research. Simufilam (hydrochloride) preferentially binds to altered FLNA and restores its native conformation, restores receptor and synaptic activities, and reduces its a7nAChR/TLR4 associations and downstream pathologies [1].
价 格:¥电议型 号:T60635产 地:中国大陆
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T5635CH7057288;化合物CH7057288CH7057288
CH7057288 is an effective and selective TRK inhibitor with an IC50 value of 1.1 nM, 7.8 nM and 5.1 nM for TRKA, TRKB and TRKC, respectively.
价 格:¥电议型 号:T5635产 地:中国大陆
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T5392TP0463518;化合物TP0463518TP0463518
TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).
价 格:¥电议型 号:T5392产 地:中国大陆
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T4635Ralinepag;化合物RalinepagAPD811;APD811
Ralinepag (APD811) is a potent, orally bioavailable agonist of non-prostanoid prostacyclin (IP) receptor, with EC50s of 8.5 nM, 530 nM and 850 nM for human and rat IP receptor and human DP1 receptor, respectively.
价 格:¥电议型 号:T4635产 地:中国大陆
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T4265AZD4635;化合物AZD4635HTL1071;HTL1071
AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).
价 格:¥电议型 号:T4265产 地:中国大陆
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T40635Desoxycarbadox;DesoxycarbadoxDesoxycarbadox
Desoxycarbadox, derived from Carbadox, is a quinoxaline-di-N-oxide antibiotic compound.
价 格:¥电议型 号:T40635产 地:中国大陆
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T40088TP0586352;TP0586352TP0586352
TP0586352 is a potent inhibitor of LpxC, exhibiting efficacy against carbapenem-resistant strains of Klebsiella pneumoniae without inducing cardiovascular risks.
价 格:¥电议型 号:T40088产 地:中国大陆
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T39635Obafistat;化合物ObafistatObafistat
Obafistat is a potent inhibitor of aldo-keto reductase AKR1C3 with an IC50 of 1.2 nM for human AKR1C3.
价 格:¥电议型 号:T39635产 地:中国大陆
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T38643Cefixime trihydrate;Cefixime trihydrateCL-284635trihydrate|||FR-17027 trihydrate|||FK-027trihydrate;
Cefixime trihydrate (FR-17027 trihydrate) is a potent antibiotic belonging to the third generation of cephalosporins. Its efficacy lies in the treatment of various bacterial infections.
价 格:¥电议型 号:T38643产 地:中国大陆