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T60004SRI-37330;化合物SRI-37330SRI-37330
SRI-37330 inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis.
价 格:¥电议型 号:T60004产 地:中国大陆
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T5S0733Picroside III;胡黄连苷IIIPicroside III
Picroside III, an iridoid glucoside found in the root of Picrorhiza scrophulariiflora Pennell (Scrophulariaceae), and its subtype Picroside II has been demonstrated to reduce apoptosis in neuronal cells and other cell types.
价 格:¥电议型 号:T5S0733产 地:中国大陆
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T5733Xylotetraose;木四糖Xylotetraose
Xylotetraose is a hydrolysis product of Xylan. Xylan is a polysaccharide made from units of xylose and contains predominantly β-D-xylose units linked as in cellulose.
价 格:¥电议型 号:T5733产 地:中国大陆
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T4733Sucrose蔗糖D(+)-Sucrose|||D-(+)-Saccharose|||蔗糖
Sucrose (D-(+)-Saccharose) is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.
价 格:¥电议型 号:T4733产 地:中国大陆
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T4463Rucaparib;瑞卡帕布AG-14447|||PF-01367338|||AG014699;AG-14447|||PF-01367338|||瑞卡帕布|||AG014699
Rucaparib (PF-01367338) is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay, and also shows binding affinity to eight other PARP.
价 格:¥电议型 号:T4463产 地:中国大陆
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T40733Kakkanin;KakkaninKakkanin
Kakkanin, a compound extracted from the roots of O. henryi, holds potential for anti-inflammatory research applications.
价 格:¥电议型 号:T40733产 地:中国大陆
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T39733Hu7691 free base;化合物 Hu7691 free baseHu7691 free base
Hu7691 free base is an orally active, potent and selective Akt inhibitor with anti-proliferative and neurogenic effects on a variety of neuroblastoma cell lines.Hu7691 free base inhibits Akt1, Akt2, and Akt3 and induces differentiation of neuroblastoma cells.
价 格:¥电议型 号:T39733产 地:中国大陆
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T38733Ald-Ph-amido-PEG11-C2-NH2;Ald-Ph-amido-PEG11-C2-NH2Ald-Ph-amido-PEG11-C2-NH2;Ald-Ph-amido-PEG11-C2-N
Ald-Ph-amido-PEG11-C2-NH2 is an 11-unit polyethylene glycol (PEG) linker that is non-cleavable. It is specifically designed for use in the synthesis of antibody-drug conjugates (ADCs).
价 格:¥电议型 号:T38733产 地:中国大陆
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T37733AMP-PNP tetralithiumAMP PNPAMP PNP tetralithium|||AMPPNP tetralithium
Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules.
价 格:¥电议型 号:T37733产 地:中国大陆
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T37339N-3-oxo-tetradecanoyl-L-Homoserine lactone;N-3-oxo-tetradecanoyl-L-Homoserine lactone3-oxo-C14-HSL||
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. Controlling bacterial infections by quenching their quorum sensing systems is a promising field of study. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by the synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-3-oxo-tetradecanoyl-L-homoserine lactone (3-oxo-C14-HSL) is
价 格:¥电议型 号:T37339产 地:中国大陆
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T37338N-3-oxo-pentanoyl-L-Homoserine lactone;N-3-oxo-pentanoyl-L-Homoserine lactoneN-3-oxo-pentanoyl-L-Hom
N-3-oxo-pentanoyl-L-Homoserine lactone is a chain-shortened derivative of the bacterial quorum sensing signaling molecule N-3-oxo-octanoyl-L-homoserine lactone .1It inhibits binding of the autoinducer N-3-oxo-hexanoyl homoserine lactone toE. colicontaining the transcription factor LuxR when used at a concentration of 230 nM.2It acts as an autoinducer to activate theV. fischeriluminescence system inE. coliwhen used at concentrations ranging from 20 to 200 nM.
价 格:¥电议型 号:T37338产 地:中国大陆
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T37337N-3-oxo-hexadecanoyl-L-Homoserine lactone;N-3-oxo-hexadecanoyl-L-Homoserine lactoneN-3-oxo-hexadecan
N-3-oxo-hexadecanoyl-L-Homoserine lactone is an unusual, substituted, long-chain N-acyl-homoserine lactone (AHL) produced by some bacteria, including strains of Agrobacterium vitis and Pseudomonas. Like other AHLs, this C16-containing form is thought to be involved in quorum sensing. Substituted, long-chain AHLs, including N-3-oxo-tetradecanoyl-L-homoserine lactone , prime for systemic acquired resistance to pathogen attack in plants.
价 格:¥电议型 号:T37337产 地:中国大陆
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T37336N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone;N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactoneN-3
Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which gener
价 格:¥电议型 号:T37336产 地:中国大陆
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T37335N-3-hydroxybutyryl-L-Homoserine lactone;N-3-hydroxybutyryl-L-Homoserine lactoneN-3-hydroxybutyryl-L-
N-3-hydroxybutyryl-L-Homoserine lactone is an N-acyl-homoserine lactone produced by the bacterium V. splendidus and has been found in sequencing batch biofilm reactors used in wastewater treatment.1,2 It is the racemic version of the V. harveyi autoinducer N-((R)-3-hydroxybutanoyl)-L-homoserine lactone.3
价 格:¥电议型 号:T37335产 地:中国大陆
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T37334(±)11,12-DiHETE;(±)11,12-DiHETE(±)11,12-DiHETE
(±)11,12-DiHETE is a dihydroxy metabolite of EPA produced by cytochrome P450-mediated epoxide formation and subsequent hydrolysis by epoxide hydrolase. Plasma levels of (±)11,12-DiHETE are increased over baseline after an oral dose of 1008 mg EPA.
价 格:¥电议型 号:T37334产 地:中国大陆
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T37333(±)11(12)-DiHET MaxSpec? Standard;(±)11(12)-DiHET MaxSpec? Standard(±)11(12)-DiHET MaxSpec? Standard
(±)-11(12)-DiHET is an oxylipin. 11(S),12(S)-DiHET and 11(R),12(R)-DiHET are vicinal diols formedviaenzymatic hydration of 11(12)-EET by cytosolic or soluble epoxide hydrolases in a non-stereoselective manner.1,2,3(±)11(12)-DiHET MaxSpec standard is a quantitative grade standard of (±)11(12)-DiHET that has been prepared specifically for mass spectrometry and related applications where quantitative reproducibility is required. The solution has been prepared gravimetrically and is supplied in a de
价 格:¥电议型 号:T37333产 地:中国大陆
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T37332(±)-N-3-Benzylnirvanol;(+/-)-N-3-苄基神经醇(±)-N-3-Benzylnirvanol
(±)-N-3-Benzylnirvanol is a racemic mixture of (+)-N-3-Benzylnirvanol and (-) -n-3-Benzylnirvanoll. (+) -n-3-Benzylnirvanol and (-) -n-3-Benzylnirvanoll are selective inhibitors of cytochrome P450 that inhibit CYP2C19, and (±) -n-3-benzylnonanol reduces plasma cholesterol levels in mice.
价 格:¥电议型 号:T37332产 地:中国大陆
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T37331PyrrophenonePyrrophenonePyrrophenone
The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid (AA) from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins (PGs) and leukotrienes (LTs). Pyrrophenone inhibits cPLA2α with an IC50 of 4.2 nM in enzyme assays and potently blocks the release of AA and the production of PGE2 and LTC4 in cells (IC50 = 24, 25, and 14 nM, respectively). Its action is reversible and selective, as py
价 格:¥电议型 号:T37331产 地:中国大陆
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T37330Pyridindolol;PyridindololPyridindolol
Pyrindolol is a bacterial metabolite that has been found inS. alboverticillatus.1It inhibits neutral β-galactosidase by 50% under acidic, but not neutral, conditions when used at a concentration of 2 μg/ml. It is selective for β-galactosidase isolated from bovine liver over β-galactosidases isolated from human, bovine, pig, and rat tissues and sialidases isolated fromC. perfringens,Streptomyces, and the H3N2 strain of influenza virus (IC50s = >250 μg/ml for all).1,2
价 格:¥电议型 号:T37330产 地:中国大陆
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T3733(E)-Methyl 4-coumarate反式对羟基肉桂酸Methyl trans-p-Coumarat|||OMpCA|||反式对羟基肉桂酸|||Methyl 4-hydroxycinnamate
(E)-Methyl 4-coumarate (OMpCA) is a predicted metabolite generated by BioTransformer1 that is produced by the metabolism of methyl 3-phenylprop-2-enoate.
价 格:¥电议型 号:T3733产 地:中国大陆