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T73328LP 218;化合物 P 218P 218
P 218 is a novel DHFR inhibitor with antimalarial activity and antifolate effects and can be used to study Buruli ulcer.
价 格:¥电议型 号:T73328L产 地:中国大陆
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T73328DHFR-IN-5;化合物 DHFR-IN-5DHFR-IN-5
DHFR-IN-5, an orally active and potent inhibitor of dihydrofolate reductase (DHFR), exhibits a K_i value of 0.54 nM against the quadruple mutant Plasmodium falciparum DHFR, demonstrating anti-malarial activity.
价 格:¥电议型 号:T73328产 地:中国大陆
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T73327Merigolix;化合物 MerigolixMerigolix
Merigolix is a potent gonadotrophin releasing hormone (GnRH) antagonist [1] .
价 格:¥电议型 号:T73327产 地:中国大陆
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T73326CB2R-IN-3;化合物 CB2R-IN-3CB2R-IN-3
CB2R-IN-3 is a selective antagonist of cannabinoid type 2 receptor (CB2R) . CB2R-IN-3 has high affinity for human CB2R and specific selectivity for CB1R. CB2R-IN-3 can be combined with CB65 , the activator of CB2R. CB2R-IN-3 effectively up-regulates the expression of anti-inflammatory cytokines and down-regulates the expression of pro-inflammatory cytokines [1] .
价 格:¥电议型 号:T73326产 地:中国大陆
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T73325MenA-IN-1;化合物 MenA-IN-1MenA-IN-1
MenA IN-1, a potent inhibitor of 1,4-dihydroxy-2-naphthoate isoprenyltransferase (MenA) from Mycobacterium tuberculosis (MTB), exhibits an IC50 value of 13 ?M and a GIC50 value of 8 ?M, suggesting its potential utility in halting the ongoing proliferation of tuberculosis.
价 格:¥电议型 号:T73325产 地:中国大陆
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T73324PARL-IN-1;化合物 PARL-IN-1PARL-IN-1
PARL-IN-1, a potent PARL inhibitor, exhibits an IC50 value of 28 nM. It effectively inhibits PARL, consequently robustly activating the PINK1/Parkin pathway and promoting PINK1/Parkin-dependent mitophagy.
价 格:¥电议型 号:T73324产 地:中国大陆
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T73323RdRP-IN-5;化合物 RdRP-IN-5RdRP-IN-5
RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1].
价 格:¥电议型 号:T73323产 地:中国大陆
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T73322TBK1-IN-1;TBK1 抑制剂 1TBK1-IN-1
TBK1-IN-1 is a specific and potent TANK-binding kinase 1 (TBK1) inhibitor (IC50: 22.4 nM) with anticancer activity.TBK1-IN-1 inhibits the expression of TBK1 downstream target genes, cxcl10 and ifnβ.
价 格:¥电议型 号:T73322产 地:中国大陆
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T73321CLK1-IN-2;化合物 CLK1-IN-2CLK1-IN-2
CLK1-IN-2, a metabolically stable Clk1 inhibitor, exhibits selective activity for Clk1 with an IC50 value of 1.7 nM. It is applicable in researching tumor, Duchenne´s muscular dystrophy, and viral infections including HIV-1 and influenza.
价 格:¥电议型 号:T73321产 地:中国大陆
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T7332(E)-2-Decenoic acid;反式-2-癸烯酸trans-2-Decenoic acid;trans-2-Decenoic acid|||反式-2-癸烯酸
(E)-2-Decenoic acid (trans-2-Decenoic acid) is an unsaturated fatty acid found in royal jelly produced from the hypopharyngeal and mandibular gland secretions of honeybees.
价 格:¥电议型 号:T7332产 地:中国大陆
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T73319BTK-IN-19;化合物 BTK-IN-19BTK-IN-19
BTK-IN-19 is a reversible BTK inhibitor with an IC 50 of <0.001 μM [1] .
价 格:¥电议型 号:T73319产 地:中国大陆
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T73318BTK-IN-18;化合物 BTK-IN-18BTK-IN-18
BTK-IN-18 is a potent, reversible inhibitor of Bruton´s tyrosine kinase (BTK) with an inhibitory concentration (IC50) of 0.002 ?M. Additionally, it effectively suppresses CD69 and CD86 expression in vivo.
价 格:¥电议型 号:T73318产 地:中国大陆
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T73317JZP-MA-13;化合物 JZP-MA-13JZP-MA-13
JZP-MA-13 is a selective α/β-hydrolase domain 6 (ABHD6) inhibitor, demonstrating impressive specificity with an IC50 value of 392 nM, and exhibits no inhibitory effects on monoacylglycerol lipase (MAGL), ABHD12, fatty acid amide hydrolase (FAAH), or other serine hydrolases. Additionally, JZP-MA-13 serves as a positron emission tomography (PET) ligand for in vivo imaging of ABHD6.
价 格:¥电议型 号:T73317产 地:中国大陆
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T73316FGFR-IN-9;化合物 FGFR-IN-9FGFR-IN-9
FGFR-IN-9 is a potent, reversible, and orally active inhibitor of the fibroblast growth factor receptor (FGFR) family, demonstrating IC50 values of 17.1 nM for FGFR4 WT, 29.6 nM for FGFR3, 30.7 nM for FGFR4 V550L, 46.7 nM for FGFR2, and 64.3 nM for FGFR1, respectively.
价 格:¥电议型 号:T73316产 地:中国大陆
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T73315(S)-ZG197;化合物 (S)-ZG197(S)-ZG197
(S)-ZG197 is a compound that acts as a highly selective activator of the Staphylococcus aureus Caseinolytic Protease P (Sa ClpP), demonstrating efficacy at a concentration of 1.4 μM (EC50).
价 格:¥电议型 号:T73315产 地:中国大陆
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T73314(R)-ZG197;化合物 (R)-ZG197(R)-ZG197
(R)-ZG197 is a compound that acts as a highly selective activator for Staphylococcus aureus Caseinolytic protease P (Sa ClpP), exhibiting an effective concentration (EC50) of 1.5 μM. It also activates Homo sapiens ClpP (Hs ClpP) with an EC50 of 31.4 μM.
价 格:¥电议型 号:T73314产 地:中国大陆
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T73313DENV-IN-9;化合物 DENV-IN-9DENV-IN-9
DENV-IN-9 is a DENV2 inhibitor with an EC 50 of 0.88 μM [1] .
价 格:¥电议型 号:T73313产 地:中国大陆
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T73311DENV-IN-7;化合物 DENV-IN-7DENV-IN-7
DENV-IN-7, a flavone analog, functions as an inhibitor of the dengue virus (DENV), demonstrating anti-dengue activity with an effective concentration (EC50) of 70 nM while exhibiting low toxicity against normal cells.
价 格:¥电议型 号:T73311产 地:中国大陆
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T73310AXL-IN-14;化合物 AXL-IN-14AXL-IN-14
AXL-IN-14 is a potent, orally active inhibitor of AXL with an IC50 of 0.8 nM that effectively suppresses Gas6/AXL-mediated cell migration and invasion, reduces the expression of p-AXL and p-AKT proteins, and demonstrates anti-tumor activity [1].
价 格:¥电议型 号:T73310产 地:中国大陆
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T7331Ursocholic acid;熊果胆酸Ursocholic acid
Ursocholic acid, a bile acid found predominantly in bile of mammals.
价 格:¥电议型 号:T7331产 地:中国大陆