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T73370RSV-IN-7;化合物 RSV-IN-7RSV-IN-7
RSV-IN-7 (example 253) is a RSV inhibitor ( EC 50 : < 0.4 μΜ) [1] .
价 格:¥电议型 号:T73370产 地:中国大陆
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T7337Kinetin riboside动力精核苷N6-Furfuryladenosine|||动力精核苷
Kinetin riboside (N6-Furfuryladenosine) can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)
价 格:¥电议型 号:T7337产 地:中国大陆
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T73369UR-MB108;化合物 UR-MB108UR-MB108
UR-MB108 is a potent and selective inhibitor of ABCG2 (BCRP), displaying an IC50 value of 79 nM, and exhibits stability in blood plasma.
价 格:¥电议型 号:T73369产 地:中国大陆
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T73368UniPR505;化合物UniPR505UniPR505
UniPR505 is a potent EphA2 antagonist (IC50: 0.95 ?M), a novel 3α-carbamoyloxy derivative with antiangiogenic properties.
价 格:¥电议型 号:T73368产 地:中国大陆
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T73367Zn(BQTC);化合物 Zn(BQTC)Zn(BQTC)
Zn(BQTC) is a potent inhibitor of both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA), causing significant damage that disrupts mitochondrial and nuclear functions sequentially. It facilitates apoptotic signaling pathways triggered by DNA damage and exhibits selective antiproliferative effects on A549R cells, rendering it useful for anticancer research [1].
价 格:¥电议型 号:T73367产 地:中国大陆
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T73364MEK-IN-5;化合物 MEK-IN-5MEK-IN-5
MEK-IN-5, a potent MEK inhibitor and nitric oxide (NO) donor, effectively decreases pMEK and pERK levels in a dose-dependent and time-dependent fashion. Additionally, it induces apoptosis in MDA-MB-231 cells.
价 格:¥电议型 号:T73364产 地:中国大陆
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T73362C-di-IMP;化合物 C-di-IMPCyclic-di-IMP;Cyclic-di-IMP
Cyclic-di-IMP (C-di-IMP), a STING agonist, serves as a research tool in tumor studies.
价 格:¥电议型 号:T73362产 地:中国大陆
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T73361RP101988;化合物 RP101988RP101988
RP101988, the principal active metabolite of Ozanimod, is a potent and selective agonist for sphingosine-1-phosphate receptor 1 (S1PR1), exhibiting half-maximal effective concentrations (EC50s) of 0.19 nM for S1PR1 and 32.8 nM for S1PR5.
价 格:¥电议型 号:T73361产 地:中国大陆
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T73360RP101442;化合物 RP101442RP101442
RP101442, the active metabolite of Ozanimod, is a selective and potent agonist of the sphingosine-1-phosphate receptor 1 (S1PR1), displaying EC50 values of 2.6 nM for S1PR1 and 171 nM for S1PR5.
价 格:¥电议型 号:T73360产 地:中国大陆
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T7336ICA-121431;化合物ICA-1214312,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl;2,2-Diphenyl-N-[4-(thiazol-2-ylsulf
ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with little or no activity against human Nav1.5 or Nav1.7 channels.
价 格:¥电议型 号:T7336产 地:中国大陆
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T73359NYX-2925;化合物 NYX-2925NYX-2925
NYX-2925, an orally active NMDAR (N-methyl-D-aspartate receptor) modulator, enhances activated Src levels and Src phosphorylation at GluN2A and GluN2B sites in the mPFC (medial prefrontal cortex), without affecting CAMKII (Ca2+/calmodulin-dependent protein kinase II) or exhibiting addictive or sedative/ataxic side effects. It is utilized in the study of various CNS (central nervous system) disorders mediated by NMDA receptors.
价 格:¥电议型 号:T73359产 地:中国大陆
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T73358(-)SHIN2;化合物 (-)SHIN2(-)SHIN2
(-)SHIN2 is the isomer of (+)SHIN2 . (+)SHIN2 is an inhibitor of serine hydroxymethyltransferase (SHMT) with antileukemic effect. (+)SHIN2 synergisty with and Methotrexate in vivo xenotransplantation models [1] .
价 格:¥电议型 号:T73358产 地:中国大陆
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T73356Ac32Az19;化合物 Ac32Az19Ac32Az19
Ac32Az19 is a potent, non-toxic, and highly selective inhibitor of Breast Cancer Resistance Protein (BCRP), demonstrating an EC50 of 13 nM in BCRP-overexpressed HEK293/R2 cells.
价 格:¥电议型 号:T73356产 地:中国大陆
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T73354TPN729MA;化合物 TPN729MATPN729 maleate;TPN729 maleate
TPN729MA (TPN729 maleate), a selective phosphodiesterase type 5 (PDE5) inhibitor, exhibits potent activity with an IC50 value of 2.28 nM and has applications in researching erectile dysfunction by impacting erectile function.
价 格:¥电议型 号:T73354产 地:中国大陆
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T73353NOS-IN-3;化合物 NOS-IN-3NOS-IN-3
NOS-IN-3 is a potent, selective, imidamide derived NOS inhibitor with an IC 50 against iNOS of 4.6 ?M, without inhibiting eNOS . NOS-IN-3 has little toxicity and can be studied in the treatment of inducible isoform involved diseases, such as septic shock [1] .
价 格:¥电议型 号:T73353产 地:中国大陆
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T73352A-943931;化合物 A-943931A-943931
A-943931, a selective and potent antagonist of the histamine H4 receptor (H4R), demonstrates affinity with pKi values of 4.6 and 3.8 nM for human and rat H4Rs, respectively. This compound exhibits anti-inflammatory and antinociceptive properties.
价 格:¥电议型 号:T73352产 地:中国大陆
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T73351CAY10581;化合物 CAY10581CAY10581
CAY10581, a derivative of pyranonaphthoquinone, serves as a highly specific and reversible uncompetitive inhibitor of IDO, demonstrating potency with an IC50 value of 55 nM.
价 格:¥电议型 号:T73351产 地:中国大陆
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T73350BAY-3827;化合物 BAY-3827BAY-3827
BAY-3827 is a potent and selective AMPK inhibitor with potential antitumor activity, showing antiproliferative activity in an androgen-dependent prostate cancer model. BAY-3827 inhibits the phosphorylation of acetyl CoA carboxylase 1.
价 格:¥电议型 号:T73350产 地:中国大陆
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T73352,3-Diaminopropionic acid;L-2,3-二氨基丙酸L-2,3-Diaminopropionic acid;L-2,3-二氨基丙酸|||L-2,3-Diaminopropioni
2,3-Diaminopropionic acid (L-2,3-Diaminopropionic acid) is an amino acid that is a precursor of antibiotics and staphyloferrin B a siderophore produced by Staphylococcus aureus.
价 格:¥电议型 号:T7335产 地:中国大陆
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T73349TTT 3002;化合物 TTT 3002TTT 3002
TTT 3002, an orally active and potent FLT3 inhibitor, efficiently suppresses FLT3 phosphorylation triggered by activating mutations at residue D835, showcasing an IC50 value of 0.2 nM. This compound is primarily utilized in acute myeloid leukemia (AML) research.
价 格:¥电议型 号:T73349产 地:中国大陆