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T73309RET-IN-20；化合物 RET-IN-20RET-IN-20
RET-IN-20, a potent RET inhibitor, demonstrates an IC50 value of 13.7 nM and effectively decreases the expression of p-Ret and p-Shc protein. Moreover, it induces apoptosis and exhibits antiproliferative and anti-tumor activity.
价 格：￥电议型 号：T73309产 地：中国大陆
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T73308Mps1-IN-5；化合物 Mps1-IN-5Mps1-IN-5
Mps1-IN-5 is a potent, orally active Mps1 inhibitor exhibiting an IC50 of 29 nM, known for triggering apoptosis and G2/M phase cell cycle arrest. This compound demonstrates antiproliferative and anti-tumor effects by inhibiting Mps1 phosphorylation and inducing DNA damage [1].
价 格：￥电议型 号：T73308产 地：中国大陆
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T73307TrkA-IN-4；化合物 TrkA-IN-4TrkA-IN-4
TrkA-IN-4, a potent, orally active and allosteric TrkA inhibitor, is a prodrug of TrkA-IN-3 . TrkA-IN-4 exhibits potent antinociceptive effects [1] .
价 格：￥电议型 号：T73307产 地：中国大陆
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T73306TrkA-IN-3；化合物 TrkA-IN-3TrkA-IN-3
TrkA-IN-3 is a potent, subselective, and allosteric inhibitor of TrkA, demonstrating significant potency with an IC50 of 22.4 nM. It exhibits over 8000-fold selectivity towards TrkA in comparison to TrkB and TrkC, making it a valuable compound for pain research.
价 格：￥电议型 号：T73306产 地：中国大陆
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T73305ALR2-IN-3；化合物 ALR2-IN-3ALR2-IN-3
ALR2-IN-2, a potent aldose reductase (ALR2) inhibitor, demonstrates IC50 values of 22 nM for rat ALR2 and 116 nM for ALR1, respectively. This compound is utilized in diabetic complications research.
价 格：￥电议型 号：T73305产 地：中国大陆
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T73304ALR2-IN-2；化合物 ALR2-IN-2ALR2-IN-2
ALR2-IN-2, a potent aldose reductase (ALR2) inhibitor, exhibits IC50 values of 27 nM for rat ALR2 and 228 nM for ALR1, respectively. This compound is utilized in the research of diabetic complications.
价 格：￥电议型 号：T73304产 地：中国大陆
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T73303BTK-IN-17；化合物 BTK-IN-17BTK-IN-17
BTK-IN-17 is a selective, orally active inhibitor of Bruton´s Tyrosine Kinase (BTK) with an inhibition concentration (IC50) value of 13.7 nM. It effectively reduces the expression of phosphorylated BTK at Tyrosine 223 (p-BTK Y223) and phosphorylated Phospholipase C Gamma 2 at Tyrosine 1217 (p-PLCγ2 Y1217), demonstrating anti-inflammatory properties.
价 格：￥电议型 号：T73303产 地：中国大陆
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T73302FAAH-IN-7；化合物 FAAH-IN-7FAAH-IN-7
FAAH-IN-7, a potent and reversible inhibitor of fatty acid amide hydrolase (FAAH), demonstrates significant neuroprotective effects, particularly by mitigating oxidative stress in 1321N1 astrocytes. With an IC50 value of 8.29 nM, it also shows notable efficacy in an ex vivo neuroinflammation model.
价 格：￥电议型 号：T73302产 地：中国大陆
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T73301ATR-IN-20；化合物 ATR-IN-20ATR-IN-20
ATR-IN-20, a potent ATM/ATR inhibitor, showcases an IC50 value of 3 nM. It also exhibits inhibitory activity against mTOR with an IC50 of 18 nM, while maintaining selectivity over PI3Kα (100 nM), ATM (100 nM), and DNA-PK (662 nM). Additionally, ATR-IN-20 has an excellent pharmacokinetic profile with an oral bioavailability (F) of 30%, and demonstrates anticancer effects.
价 格：￥电议型 号：T73301产 地：中国大陆
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T73300AXL-IN-13；化合物AXL-IN-13AXL-IN-13
AXL-IN-13 is a potent and orally active AXL inhibitor with an IC50 value of 1.6 nM and a Kd value of 0.26 nM.AXL-IN-13 exhibits anticancer activity, reverses TGF-β1-induced epithelial-mesenchymal transition (EMT) and inhibits cancer cell migration and invasion.
价 格：￥电议型 号：T73300产 地：中国大陆
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T7330Nucleozin化合物Nucleozin[4-(2-氯-4-硝基苯基)-1-哌嗪基](5-甲基-3-苯基-4-异噁唑基)-甲酮
Nucleozin targets influenza A nucleoprotein (NP), a multifunctional, RNA-binding protein necessary for virus replication.
价 格：￥电议型 号：T7330产 地：中国大陆
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T72733Geissoschizoline；化合物 Geissoschizoline(+)-Geissoschizoline；(+)-Geissoschizoline
Geissoschizoline ((+)-Geissoschizoline), with IC50 values of 20.40 ?M for human AChE and 10.21 ?M for BChE, functions as a potent inhibitor and emerges as a promising multi-target prototype for research into preventing neurodegeneration and restoring neurotransmission. Additionally, it serves as a potent anti-inflammatory agent.
价 格：￥电议型 号：T72733产 地：中国大陆
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T71733VU0606170；化合物 VU0606170VU0606170
VU0606170 is a slack channels inhibitor and was shown to successfully decrease the malfunctioning spontaneous firing rate of cortical neurons, providing a potential avenue for achieving an anti-epileptic effect not previously attainable.
价 格：￥电议型 号：T71733产 地：中国大陆
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T70733APX2009；化合物 APX2009APX2009
APX2009 is a second-generation APE1/Ref-1 redox-specific inhibitor. APX2009 significantly reduces NFkB transcriptional activity, survivin mRNA, and survivin protein levels. APX2009 decreases prostate cancer cell proliferation and induces cell cycle arrest.
价 格：￥电议型 号：T70733产 地：中国大陆
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T69810N-2733 HCl；化合物 N-2733 HClN-2733 HCl
N-2733 HCl is a nuclear factor (NF)-kappaB activation inhibitor.
价 格：￥电议型 号：T69810产 地：中国大陆
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T69733LM9；化合物 LM9LM9
LM9 is a MyD88 inhibitor which prevents atherosclerosis by regulating inflammatory responses and oxidative stress in macrophages.
价 格：￥电议型 号：T69733产 地：中国大陆
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T68733Ono 3307 Free Base；化合物 Ono 3307 Free BaseOno 3307 Free Base
Ono 3307 Free Base is a new synthetic protease inhibitor
价 格：￥电议型 号：T68733产 地：中国大陆
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T67733BT44；化合物RET agonist BT44BT44
BT44 is a novel, second-generation glial cell linederived neurotropic factor mimetic with improved biological activity and is a lead compound for the treatment of neurodegenerative disorders.
价 格：￥电议型 号：T67733产 地：中国大陆
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T67339Methyl 2-methoxy-5-sulfamoylbenzoate；化合物 Methyl 2-methoxy-5-sulfamoylbenzoateMethyl 2-methoxy-5-sulf
Methyl 2-methoxy-5-sulfamoylbenzoate is a useful organic compound for research related to life sciences. The catalog number is T67339 and the CAS number is 33045-52-2.
价 格：￥电议型 号：T67339产 地：中国大陆
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T673382,7-Dihydroxynaphthalene；化合物 2,7-Dihydroxynaphthalene2,7-Dihydroxynaphthalene
2,7-Dihydroxynaphthalene is a useful organic compound for research related to life sciences. The catalog number is T67338 and the CAS number is 582-17-2.
价 格：￥电议型 号：T67338产 地：中国大陆
