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T73396ARS-2102;化合物 ARS-2102ARS-2102
ARS-2102 is a potent covalent KRAS G12C inhibitor for use in cancer research [1] .
价 格:¥电议型 号:T73396产 地:中国大陆
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T73395ASPER-29;化合物 ASPER-29ASPER-29
ASPER-29, an analog of Asperphenamate, acts as a dual inhibitor of cathepsin L and S, displaying inhibitory concentrations (IC50) of 6.03 μM and 5.02 μM, respectively. This compound is utilized in the study of cancer migration and invasion.
价 格:¥电议型 号:T73395产 地:中国大陆
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T73394BAY-7081;化合物 BAY-7081BAY-7081
BAY-7081 is a cyanopyridone-based compound that functions as a potent, selective, and orally active PDE9A inhibitor, demonstrating an inhibition concentration (IC 50) of 15 nM. It exhibits solubility in oral formulations.
价 格:¥电议型 号:T73394产 地:中国大陆
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T73392TUL01101;化合物 TUL01101TUL01101
TUL01101, a potent, selective, and orally active inhibitor of JAK1, exhibits half-maximal inhibitory concentrations (IC50s) of 3 nM for JAK1, 37 nM for JAK2, 1,517 nM for JAK3, and 36 nM for TYK2. This compound is utilized in the research of rheumatoid arthritis.
价 格:¥电议型 号:T73392产 地:中国大陆
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T73391BLM-IN-2;化合物 BLM-IN-2BLM-IN-2
BLM-IN-2, a Bloom´s Syndrome Protein (BLM) inhibitor, exhibits an IC50 of 0.8 μM and shows efficacy in suppressing proliferation, invasion, cell cycle arrest, and apoptosis in colorectal cancer (CRC) cells, making it a potential candidate for CRC research.
价 格:¥电议型 号:T73391产 地:中国大陆
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T73390I-BET432;化合物 I-BET432I-BET432
I-BET432, a BET inhibitor, targets both the N-terminal (BD1) and C-terminal (BD2) bromodomains of BRD4, exhibiting pIC50 values of 7.5 and 7.2, respectively. As an orally administered candidate, I-BET432 holds potential for research in various oncology and inflammatory diseases.
价 格:¥电议型 号:T73390产 地:中国大陆
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T7339Angiotensin (1-7);化合物Angiotensin 1-7Ang-(1-7)|||Angiotensin 1-7|||ASP-ARG-VAL-TYR-ILE-HIS-PRO;Ang-(1
Angiotensin (1-7) (ASP-ARG-VAL-TYR-ILE-HIS-PRO) is a synthetic heptapeptide identical to endogenous angiotensin-(1-7) , inhibits purified canine ACE activity (IC50=0.65 μM) with vasodilator and antiproliferative activities.
价 格:¥电议型 号:T7339产 地:中国大陆
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T7338LDHBP;紫外线吸收剂Benzoresorcinol;紫外线吸收剂|||Benzoresorcinol
DHBP (Benzoresorcinol) is an WalKR TCS activator. It works via targeting walk and selectively promoting the lysostaphin-induced lysis activity of the Newman wild-type strain.
价 格:¥电议型 号:T7338L产 地:中国大陆
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T73389RGT-068A;化合物 RGT-068ARGT-068A
RGT-068A is a potent, selective and oral bioavailable MALT1 inhibitor [1] .
价 格:¥电议型 号:T73389产 地:中国大陆
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T73384GLPG3970;化合物 GLPG3970GLPG3970
GLPG3970 GLPG3970 is a novel orally available selective dual SIK2/SIK3 inhibitor.GLPG3970 has potential anti-inflammatory activity for the study of autoimmune diseases.
价 格:¥电议型 号:T73384产 地:中国大陆
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T73382SZM-1209;化合物 SZM-1209SZM-1209
SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM. It demonstrates substantial anti-necroptotic efficacy with an EC50 of 22.4 ± 8.1 nM and possesses therapeutic effects against systemic inflammatory response syndrome (SIRS) and acute lung injury (ALI) [1].
价 格:¥电议型 号:T73382产 地:中国大陆
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T73381BGB-8035;化合物 BGB-8035BGB-8035
BGB-8035 is an orally administered, highly selective inhibitor of Bruton´s tyrosine kinase (BTK), exhibiting IC50 values of 1.1 nM for BTK, 99 nM for TEC, and 621 nM for EGFR. It demonstrates antitumor and anti-arthritis effects, showcasing potential for research in B-cell malignancies and autoimmune diseases.
价 格:¥电议型 号:T73381产 地:中国大陆
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T73380CK2-IN-6;化合物 CK2-IN-6CK2-IN-6
CK2-IN-6, a powerful inhibitor of protein kinase CK2, shows promise for research in cancer, along with conditions related to kinases such as inflammation, pain, and specific immune diseases.
价 格:¥电议型 号:T73380产 地:中国大陆
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T73379TMV-IN-1;化合物 TMV-IN-1TMV-IN-1
TMV-IN-1, a chalcone derivative, serves as an inhibitor of the tobacco mosaic virus (TMV), demonstrating effective therapeutic and protective activities, with EC50 values of 70.7 μg/mL and 60.8 μg/mL, respectively. This compound is applicable in research related to infection, inflammation, and tumor [1].
价 格:¥电议型 号:T73379产 地:中国大陆
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T73377IGUANA-1;化合物 IGUANA-1IGUANA-1
IGUANA-1, a potent ALDH1B1 inhibitor, effectively targets this mitochondrial enzyme involved in promoting colorectal and pancreatic cancer. It exhibits significant inhibition against cancer cells.
价 格:¥电议型 号:T73377产 地:中国大陆
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T73375CK2-IN-4;CK2抑制剂4CK2-IN-4
CK2-IN-4 is a protein kinase (CK2) inhibitor with an IC50 value of 8.6 ?M. CK2-IN-4 has potential anticancer ah and anti-inflammatory activity for the study of viral infections and glomerulonephritis diseases.
价 格:¥电议型 号:T73375产 地:中国大陆
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T73374TP-030-1;化合物 TP-030-1TP-030-1
TP-030-1, an inhibitor of RIPK1, exhibits potent activity against hRIPK1 (human RIPK1) with a Ki value of 3.9 nM and against mRIPK1 (mouse RIPK1) with an IC50 value of 4.2 μM. This compound is instrumental in the research of inflammatory and neurodegenerative diseases.
价 格:¥电议型 号:T73374产 地:中国大陆
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T73373TP-030-2;化合物 TP-030-2TP-030-2
TP-030-2 is a RIPK1 inhibitor (human K i =0.43 nM ; mouse IC 50 =100 nM) [1] [2] .
价 格:¥电议型 号:T73373产 地:中国大陆
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T73372GNE-2256;化合物 GNE-2256GNE-2256
GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.
价 格:¥电议型 号:T73372产 地:中国大陆
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T73371BAY-3153;化合物 BAY-3153BAY-3153
BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) [1] .
价 格:¥电议型 号:T73371产 地:中国大陆